Results 61 to 70 of about 225,840 (271)

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Evaluation of MALDI-TOF for identification of Vibrio cholerae and Vibrio parahaemolyticus from growth on agar media

Applied Microbiology and Biotechnology
Two methods were compared for their ability to accurately identify Vibrio species of interest: whole genome sequencing as the reference method and MALDI-TOF MS (matrix-assisted laser desorption/ionization-time of flight mass spectrometry) proteome ...
Swapan Banerjee, Annika Flint, Madeleine B. Brosseau, Kelly Weedmark, Bojan Shutinoski   +4 more
doaj   +1 more source

Candida auris metabolism and growth preferences in physiologically relevant skin-like conditions

mBio
Candida auris is an opportunistic, multidrug-resistant yeast with a high capacity for human skin colonization in healthcare settings, which can lead to subsequent infections with high mortality rates.
Jonathan P. Nicklas, Clay Deming, ShihQueen Lee-Lin, Sean Conlan, Zeyang Shen, Ryan A. Blaustein, Julia A. Segre   +6 more
doaj   +1 more source

Fast and accurate average genome size and 16S rRNA gene average copy number computation in metagenomic data

BMC Bioinformatics, 2019
Background Metagenomics caused a quantum leap in microbial ecology. However, the inherent size and complexity of metagenomic data limit its interpretation.
Emiliano Pereira-Flores, Frank Oliver Glöckner, Antonio Fernandez-Guerra   +2 more
doaj   +1 more source

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

Advanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia, Chenfei Kong, Xiaoming Zhao, Naixu Shi, Jinlan Jiang, Ping Li   +5 more
wiley   +1 more source

The hidden genetic reservoir: structural variants as drivers of marine microbial and viral microdiversity

Environmental Microbiome
Background Intraspecific genetic diversity is fundamental to understanding microbial adaptation, evolution, and contributions to ecosystem stability.
Jose M. Haro-Moreno, Juan J. Roda-Garcia, Carmen Molina-Pardines, Mario López-Pérez   +3 more
doaj   +1 more source

Inhibition of NHEJ repair by type II-A CRISPR-Cas systems in bacteria

Nature Communications, 2017
The double-strand breaks generated by CRISPR-Cas systems are the target of multiple DNA repair pathways. Here the authors find incompatibility between NHEJ and type II-A CRISPR-Cas systems due to Csn2 mediated inhibition of end-joining.
Aude Bernheim, Alicia Calvo-Villamañán, Clovis Basier, Lun Cui, Eduardo P. C. Rocha, Marie Touchon, David Bikard   +6 more
doaj   +1 more source

Bridging the gap between omics and earth system science to better understand how environmental change impacts marine microbes [PDF]

, 2015
The advent of genomic-, transcriptomic- and proteomic-based approaches has revolutionized our ability to describe marine microbial communities, including biogeography, metabolic potential and diversity, mechanisms of adaptation, and phylogeny and ...
Alexander, Allen, Alvain, Ashworth, Baas-Becking, Bach, Barton, Behrenfeld, Behrenfeld, Behrenfeld, Bennett, Bihan, Bochdanovits, Bopp, Bowler, Boyd, Boyd, Boyle, Bruggeman, Buitenhuis, Buitenhuis, Buitenhuis, Button, Chappell, Coesel, Coleman, Collins, Corellou, Daines, Davis, Delong, Derelle, Deutsch, Dinsdale, Djouani-Tahri el, Doney, Draghi, Dufresne, Dutkiewicz, Edwards, Elena, Fabris, Follows, Follows, Franklin, Ghiglione, Gilbert, Gould, Hartmann, Hashioka, Hickman, Hillebrand, Hindle, Hof, Hood, House, Hutchins, Huysman, Hüner, Johnson, Juhas, Juranek, Kashtan, Kim, Kiorboe, Knoop, Kroeker, Krumholz, Ladau, Lanfear, Langer, Laws, Ley, Lindell, Litchman, Litchman, Loeuille, Lohbeck, Luo, Marchetti, Marinov, Martiny, Masotti, McKew, Mock, Monnier, Monteiro, Moore, Moulager, O'Neill, Oschlies, Patel, Piotrowski, Plummer, Poloczanaska, Quere, Raes, Ral, Raven, Raven, Raymond, Reed, Ridgwell, Riley, Rocap, Saito, Schaum, Schlichting, Schmidt, Shuter, Smetacek, Sorokina, Steuer, Stramma, Talmy, Taucher, Taylor, Thomas, Toseland, Traylor-Knowles, Troein, Vallino, Veluchamy, Via, Vogt, Vu, Webb, Wecker, Wijffels, Zinser   +129 more
core   +1 more source

Rapid Remodeling of the Human Gut Microbiome in Response to Short‐Term Animal Product Restriction and Associations with Host Molecular Phenotypes

Advanced Science, EarlyView.
A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil, Maria Anezaki, Alexandros Simistiras, Stavros Glentis, Nikolaos Scarmeas, Pantelis Hatzis, Konstantinos Rouskas, Antigone S. Dimas   +7 more
wiley   +1 more source

Phages Actively Challenge Niche Communities in Antarctic Soils

mSystems, 2020
By modulating the structure, diversity, and trophic outputs of microbial communities, phages play crucial roles in many biomes. In oligotrophic polar deserts, the effects of katabatic winds, constrained nutrients, and low water availability are known to ...
Oliver K. I. Bezuidt, Pedro Humberto Lebre, Rian Pierneef, Carlos León-Sobrino, Evelien M. Adriaenssens, Don A. Cowan, Yves Van de Peer, Thulani P. Makhalanyane   +7 more
doaj   +3 more sources