Results 81 to 90 of about 225,840 (271)

Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis

Advanced Science, EarlyView.
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen, Hao Shi, Junxian He, Ziyu Liu, Yuanyuan Zhu, Xiaoyan Liang, Guihua Liu, Xing Yang   +7 more
wiley   +1 more source

Assembling metagenomes, one community at a time

BMC Genomics, 2017
Background Metagenomics allows unprecedented access to uncultured environmental microorganisms. The analysis of metagenomic sequences facilitates gene prediction and annotation, and enables the assembly of draft genomes, including uncultured members of a
Andries Johannes van der Walt, Marc Warwick van Goethem, Jean-Baptiste Ramond, Thulani Peter Makhalanyane, Oleg Reva, Don Arthur Cowan   +5 more
doaj   +1 more source

Microbial Nitrogen Cycling in Antarctic Soils

Microorganisms, 2020
The Antarctic continent is widely considered to be one of the most hostile biological habitats on Earth. Despite extreme environmental conditions, the ice-free areas of the continent, which constitute some 0.44% of the total continental land area ...
Max Ortiz, Jason Bosch, Clément Coclet, Jenny Johnson, Pedro Lebre, Adeola Salawu-Rotimi, Surendra Vikram, Thulani Makhalanyane, Don Cowan   +8 more
doaj   +1 more source

16S rRNA gene profiling and genome reconstruction reveal community metabolic interactions and prebiotic potential of medicinal herbs used in neurodegenerative disease and as nootropics. [PDF]

, 2019
The prebiotic potential of nervine herbal medicines has been scarcely studied. We therefore used anaerobic human fecal cultivation to investigate whether medicinal herbs commonly used as treatment in neurological health and disease in Ayurveda and other ...
Albayrak, Levent, Chopra, Deepak, Fofanov, Yuriy, Iablokov, Stanislav N, Khanipov, Kamil, Mills, Paul J, Peterson, Christine Tara, Peterson, Scott N, Rodionov, Dmitry A, Sharma, Vandana, Uchitel, Sasha   +10 more
core   +5 more sources

Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay

Advanced Science, EarlyView.
This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao, Ruiqi Zhang, Rujun Wei, Huimin Fan, Yongfei Hu, Wenyu Shi, Jinfeng Wang   +6 more
wiley   +1 more source

Nutrient cross-feeding in the microbial world. [PDF]

, 2014
The stability and function of a microbial community depends on nutritional interactions among community members such as the cross-feeding of essential small molecules synthesized by a subset of the population.
Seth, Erica C, Taga, Michiko E
core   +2 more sources

Genome‐Wide Association Study Reveals Insect Genetics and Microbial Symbiont Effects on Susceptibility of Diaphorina citri to the Citrus Greening Pathogen, Candidatus Liberibacter Asiaticus

Advanced Science, EarlyView.
This study investigates the genetic and microbial factors influencing the susceptibility of Diaphorina citri to the citrus greening pathogen Candidatus Liberibacter asiaticus (CLas), employing a microbiome Genome Wide Association Study. The research identifies a key gene encoding an MFS‐type transporter contributing to CLas infectivity and abundance in
Kai Liu, Qingcui He, Zeyue Lin, Shixuan Huang, Zichun Zhong, Pingyang Zhu, Mengge Gao, Luyao Zhao, Han Jin, Guiting Wu, Gurr M. Geoff, Qunxin Han, Rui Pang   +12 more
wiley   +1 more source

Coupled Phylogenetic and Functional Enrichment in the Tomato Rhizosphere Microbiome

Phytobiomes Journal
Plant–microbe interactions occur mainly in the rhizosphere, a hot spot of microbial activity and diversity, and the outcome of these interactions can significantly affect plant productivity.
Silvia Talavera-Marcos, Ramón Gallego, Rubén Chaboy-Cansado, Alberto Rastrojo, Daniel Aguirre de Cárcer   +4 more
doaj   +1 more source

BLADE‐ON‐PETIOLE Genes Enable Genetic Bottleneck Mitigation Through Cross‐Species Repurposing of Floral Persistence Traits

Advanced Science, EarlyView.
This study shows that BLADE‐ON‐PETIOLE (BOP) proteins regulate floral abscission and senescence in tomato by interacting with TFAM1 to form transcriptional condensates controlling the ARABIDOPSIS THALIANA HOMEOBOX GENE 1 (ATH1)‐mediated abscission pathway.
Nan Xiao, Qianwen Lyu, Tinghao Zhang, Yupan Zou, Yue Xie, Dandan Yang, Cao Xu, Xiaozhen Huang   +7 more
wiley   +1 more source

Comparative genomics of Burkholderia multivorans, a ubiquitous pathogen with a highly conserved genomic structure [PDF]

, 2017
The natural environment serves as a reservoir of opportunistic pathogens. A well-established method for studying the epidemiology of such opportunists is multilocus sequence typing, which in many cases has defined strains predisposed to causing infection.
Peeters, Charlotte, Cooper, Vaughn S, Hatcher, Philip J, Verheyde, Bart, Carlier, Aurélien, Vandamme, Peter   +5 more
core   +3 more sources