Results 11 to 20 of about 360,618 (254)

GenomicGapID: leveraging spatial distribution of conserved genomic sites for broad-spectrum microbial identification [PDF]

open access: yesMicrobiology Spectrum
Bacterial detection and identification methods can be broadly classified as either untargeted with expansive taxonomic coverage or targeted with narrow taxonomic focus.
Vishwaratn Asthana   +8 more
doaj   +2 more sources

Metagenomic Pyrosequencing and Microbial Identification [PDF]

open access: yesClinical Chemistry, 2009
Abstract Background: The Human Microbiome Project has ushered in a new era for human metagenomics and high-throughput next-generation sequencing strategies. Content: This review describes evolving strategies in metagenomics, with a special emphasis on the core technology of DNA pyrosequencing.
Joseph F, Petrosino   +4 more
openaire   +2 more sources

Reconstruction of small subunit ribosomal RNA from high‐throughput sequencing data: A comparative study of metagenomics and total RNA sequencing

open access: yesMethods in Ecology and Evolution, 2023
The small subunit (SSU) ribosomal RNA (rRNA) is the most commonly used marker for the identification of microbial taxa, but its full‐length reconstruction from high‐throughput sequencing (HTS) data remains challenging.
Christopher A. Hempel   +4 more
doaj   +1 more source

Application and Perspectives of MALDI–TOF Mass Spectrometry in Clinical Microbiology Laboratories

open access: yesMicroorganisms, 2021
Early diagnosis of severe infections requires of a rapid and reliable diagnosis to initiate appropriate treatment, while avoiding unnecessary antimicrobial use and reducing associated morbidities and healthcare costs.
Eva Torres-Sangiao   +2 more
doaj   +1 more source

Algorithms push forward the application of MALDI–TOF mass fingerprinting in rapid precise diagnosis

open access: yesView, 2023
Macromolecular mass fingerprinting using matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry is a quick tool for biochemical analysis.
Yingdi Zhu, Hubert H. Girault
doaj   +1 more source

Computational Identification of Operons in Microbial Genomes [PDF]

open access: yesGenome Research, 2001
By applying graph representations to biochemical pathways, a new computational pipeline is proposed to find potential operons in microbial genomes. The algorithm relies on the fact that enzyme genes in operons tend to catalyze successive reactions in metabolic pathways.
Yu, Zheng   +4 more
openaire   +2 more sources

Identification of microbial DNA in human cancer [PDF]

open access: yesBMC Medical Genomics, 2009
Abstract Background Microorganisms have been associated with many types of human diseases; however, a significant number of clinically important microbial pathogens remain to be discovered. Methods We have developed a genome-wide approach, called Digital Karyotyping ...
Vogelstein Bert   +14 more
openaire   +3 more sources

Microbial Antigen Identification and Vaccine Delivery Systems

open access: yesVaccines, 2022
Vaccine efficacy and immunogenicity depend on the host, pathogen, and pathogenesis of the disease [...]
Paulo J. G. Bettencourt   +1 more
openaire   +4 more sources

Compositional Quality and Potential Gastrointestinal Behavior of Probiotic Products Commercialized in Italy

open access: yesFrontiers in Medicine, 2018
Recent guidelines indicate that oral probiotics, living microorganisms able to confer a health benefit on the host, should be safe for human consumption, when administered in a sufficient amount, and resist acid and bile to exert their beneficial effects
Alessandra Vecchione   +6 more
doaj   +1 more source

Microbial Assimilation of Hydrocarbons: Identification of Phospholipids [PDF]

open access: yesJournal of Bacteriology, 1970
The distribution of phospholipids derived from Micrococcus cerificans was determined under a variety of nutritive conditions. Cells were grown with hexadecane, heptadecane, or acetate serving as the sole carbon source.
R A, Makula, W R, Finnerty
openaire   +2 more sources

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