Results 51 to 60 of about 728,080 (310)
Metabolic engineering of microorganisms for urban waste valorization
Case Studies in Chemical and Environmental Engineering, 2021 Waste management is one the major challenges throughout the world. Microbial conversion of urban organic waste into valuable by-products can be used as an approach to advance circular bioeconomy and sustainable development.
Imen Ben Tahar, Patrick Fickers
doaj +1 more source
Changes in the genetic requirements for microbial interactions with increasing community complexity. [PDF]
, 2018 Microbial community structure and function rely on complex interactions whose underlying molecular mechanisms are poorly understood. To investigate these interactions in a simple microbiome, we introduced E. coli into an experimental community based on a
Dutton, Rachel J +2 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Paths reunited: initiation of the classical and lectin pathways of complement activation [PDF]
, 2010 Understanding the structural organisation and mode of action of the initiating complex of the classical pathway of complement activation (C1) has been a central goal in complement biology since its isolation almost 50 years ago.
Keeble, Anthony H. +4 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Scientific ReportsIn the present study, we characterise a strain isolated from the wastewater aeration lagoon of a sugar processing plant in Schleswig (Northern Germany) by Heinz Schlesner. As a pioneer in planctomycetal research, he isolated numerous strains belonging to
Carmen E. Wurzbacher +5 more
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Microorganisms, 2019 Recombinant protein production represents a multibillion-dollar market. Therefore, it constitutes an important research field both in academia and industry.
Marie Vandermies, Patrick Fickers
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Helper-Like Type-1 Innate Lymphoid Cells in Inflammatory Bowel Disease
Frontiers in Immunology, 2022 Inflammatory bowel disease (IBD) is an idiopathic condition characterized by chronic relapsing inflammation in the intestine. While the precise etiology of IBD remains unknown, genetics, the gut microbiome, environmental factors, and the immune system ...
Diana Coman +3 more
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Substrate utilization and secondary metabolite biosynthesis in the phylum Planctomycetota
Applied Microbiology and BiotechnologyThe phylum Planctomycetota is changing our understanding of bacterial metabolism, driving critical biogeochemical processes through the transformation of complex polymeric substrates into valuable bioactive compounds.
Madeleine Kündgen +2 more
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