Results 41 to 50 of about 3,397,292 (246)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The evolutionary ecology of model microbial communities [PDF]
, 2009 textThe biological world is complex. Communities contain a multitude of interacting species, while populations contain extensive genetic variation. How much complexity must one consider to understand patterns and processes of interest?
Harcombe, William Russell
core
Microbial Colonization of Minerals in Marine Sediments – Method Development and Ecological Significance [PDF]
, 2011 Interactions between microorganisms and minerals significantly impact microbial diversity and geochemical cycles in diverse settings. However, methodological difficulty has inhibited past study of microbe–mineral interactions in fine-grained subsurface ...
Harrison, Benjamin Kimball
core +1 more source
Scientific ReportsFour non-pigmented, off-white to ivory strains, SH527T, SH661T, SH664T and SH668T, have been isolated from sewage sludge or leakage water of a compost heap in Northern Germany as part of an isolation campaign conducted by Heinz Schlesner, Kiel University
Nicolai Kallscheuer +4 more
doaj +1 more source
Natural products in the predatory defence of the filamentous fungal pathogen Aspergillus fumigatus
Beilstein Journal of Organic Chemistry, 2021 The kingdom of fungi comprises a large and highly diverse group of organisms that thrive in diverse natural environments. One factor to successfully confront challenges in their natural habitats is the capability to synthesize defensive secondary ...
Jana M. Boysen +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Scientific ReportsThe strain collection of Heinz Schlesner (Kiel University, Germany) largely consists of budding bacteria collected from the 1980s to early 2000s. It still holds an untapped diversity of bacteria with uncommon morphologies and cell division modes.
Nicolai Kallscheuer +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Microbial glycan microarrays define key features of host-microbial interactions [PDF]
, 2014 Genomic approaches continue to provide unprecedented insight into the microbiome, yet host immune interactions with diverse microbiota can be difficult to study.
Jean-Philippe Gourdine +27 more
core +1 more source
Synergistic interactions in the microbial world [PDF]
Antonie van Leeuwenhoek, 2002 After several decades of microbiological research has focused on pure cultures, synergistic effects between different types of microorganisms find increasing interest. Interspecies interactions between prokaryotic cells have been studied into depth mainly with respect to syntrophic cooperations involved in methanogenic degradation of electron-rich ...
openaire +3 more sources