Results 21 to 30 of about 354,203 (268)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

A novel strain isolated from methane seeps in the Kattegat belongs to the planctomycetal species Novipirellula methanifontis sp. nov.

Scientific Reports
Here, we present the bacterial isolate SH528T, a planctomycetal strain from the collection of Heinz Schlesner (Kiel University), a pioneer in the research on budding bacteria. Genomic and physiological features of the novel strain are characterized along
Myriel Staack, Tom Haufschild, Jonathan Hammer, Nicolai Kallscheuer, Gaurav Kumar, Christian Jogler   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Three strains isolated from Northern Germany constitute the novel genera Njordella and Rania in the family Pirellulaceae

Scientific Reports
This study reports the characterization of three novel species belonging to the two newly established genera Njordella gen. nov. and Rania gen. nov. in the family Pirellulaceae within the phylum Planctomycetota.
Myriel Staack, Tom Haufschild, Jonathan Hammer, Nicolai Kallscheuer, Gaurav Kumar, Christian Jogler   +5 more
doaj   +1 more source

Stimulation of Fengycin-Type Antifungal Lipopeptides in Bacillus amyloliquefaciens in the Presence of the Maize Fungal Pathogen Rhizomucor variabilis

Frontiers in Microbiology, 2017
Most isolates belonging to the Bacillus amyloliquefaciens subsp. plantarum clade retain the potential to produce a vast array of structurally diverse antimicrobial compounds that largely contribute to their efficacy as biocontrol agents against numerous ...
Parent Zihalirwa Kulimushi, Parent Zihalirwa Kulimushi, Anthony Argüelles Arias, Laurent Franzil, Sébastien Steels, Marc Ongena   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The novel taxon Lacunimicrobium album gen. nov., sp. nov. is constituted by three planctomycetotal strains isolated from freshwater habitats in Northern Germany

Scientific Reports
The majority of characterized members of the phylum Planctomycetota were isolated from marine habitats. To expand the open collection of limnic planctomycetes, we here characterize three isolates from the strain collection of Heinz Schlesner (Kiel ...
Moses Kabuu, Gaurav Kumar, Tom Haufschild, Jonathan Hammer, Christian Jogler, Nicolai Kallscheuer   +5 more
doaj   +1 more source

Bacterial Adaptation during Chronic Respiratory Infections

Pathogens, 2015
Chronic lung infections are associated with increased morbidity and mortality for individuals with underlying respiratory conditions such as cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD). The process of chronic colonisation allows
Louise Cullen, Siobhán McClean
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Characterisation of Kothea flammea gen. nov., sp. nov., a planctomycete of the family Pirellulaceae isolated from Fjord Schlei in the Baltic Sea

Scientific Reports
The flame-like reddish to orange-pigmented planctomycetal strain SH139T was isolated from brackish water obtained from Fjord Schlei in Northern Germany as part of an isolation effort led by Heinz Schlesner at Kiel University between the 1980s and early ...
Gaurav Kumar, Nicolai Kallscheuer, David Appiah, Jonathan Hammer, Tom Haufschild, Christian Jogler   +5 more
doaj   +1 more source