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Physiological limitations and opportunities in microbial metabolic engineering
Nature Reviews Microbiology, 2021Metabolic engineering can have a pivotal role in increasing the environmental sustainability of the transportation and chemical manufacturing sectors. The field has already developed engineered microorganisms that are currently being used in industrial-scale processes.
José Montaño López +2 more
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Undigested dietary and endogenous proteins, as well as unabsorbed amino acids, can move from the terminal part of the ileum into the large intestine, where they meet a dense microbial population. Exfoliated cells and mucus released from the large intestine epithelium also supply nitrogenous material to this microbial population.
François Blachier
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Physiology, Metabolism, and Fossilization of Hot-Spring Filamentous Microbial Mats [PDF]
The evolutionarily ancient Aquificales bacterium Sulfurihydrogenibium spp. dominates filamentous microbial mat communities in shallow, fast-flowing, and dysoxic hot-spring drainage systems around the world.
Mayandi Sivaguru +2 more
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Use of genome‐scale metabolic models for understanding microbial physiology [PDF]
The exploitation of microorganisms in industrial, medical, food and environmental biotechnology requires a comprehensive understanding of their physiology. The availability of genome sequences and accumulation of high‐throughput data allows gaining understanding of microbial physiology at the systems level, and genome‐scale metabolic models represent a
Sérgio Bordel +2 more
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Microbial physiology-based model of ethanol metabolism in subsurface sediments
Journal of Contaminant Hydrology, 2011A biogeochemical reaction model was developed based on microbial physiology to simulate ethanol metabolism and its influence on the chemistry of anoxic subsurface environments. The model accounts for potential microbial metabolisms that degrade ethanol, including those that oxidize ethanol directly or syntrophically by reducing different electron ...
Qusheng Jin, Eric Roden
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Physiology of microbial cells and metabolic engineering
Microbiology, 2000This review is devoted to the problems of the physiology and cell biology of microorganisms in relation to metabolic engineering. The latter is considered as a branch of fundamental and applied biotechnology aimed at controlling microbial metabolism by methods of genetic engineering and classical genetics and based on intimate knowledge of cell ...
E L, Golovlev, L A, Golovleva
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Secondary Metabolism and Microbial Physiology
1985Publisher Summary This chapter discusses the biochemical similarities and differences between primary and secondary metabolism. The known secondary metabolites are divided into three categories according to the perceived source of the carbon from which their skeletons are derived.
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Microbiological Research, 2023
Attenuating the Taxol productivity of fungi with the subculturing and storage under axenic conditions is the challenge that halts the feasibility of fungi to be an industrial platform for Taxol production. This successive weakening of Taxol productivity by fungi could be attributed to the epigenetic down-regulation and molecular silencing of most of ...
Nabil Z, Mohamed +3 more
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Attenuating the Taxol productivity of fungi with the subculturing and storage under axenic conditions is the challenge that halts the feasibility of fungi to be an industrial platform for Taxol production. This successive weakening of Taxol productivity by fungi could be attributed to the epigenetic down-regulation and molecular silencing of most of ...
Nabil Z, Mohamed +3 more
openaire +2 more sources
Metabolomics: A Microbial Physiology and Metabolism Perspective
2018Metabolomics is valuable for studying microbial metabolism, which is often used to elucidate biological functions. Effective application of metabolomics is enhanced by fundamental understanding of microbial physiology and metabolism. This review briefly highlights important aspects of metabolism that are essential for designing and executing effective ...
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