Results 71 to 80 of about 326,888 (301)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Influence of River Inflow and Microbial Activity on Distribution of Dissolved Organic Carbon in the Northern Part of Ariake Sea, Kyushu, Japan

Journal of Water and Environment Technology, 2021
To identify the factors controlling the distribution of dissolved organic carbon (DOC) in the northern Ariake Sea (Japan), we measured DOC, salinity and chlorophyll a (Chl.
Koji Uchino, Koichiro Mori, Natsu Fukushima, Hiroyuki Takasu   +3 more
doaj   +1 more source

Native Plasmid-Encoded Mercury Resistance Genes Are Functional and Demonstrate Natural Transformation in Environmental Bacterial Isolates. [PDF]

, 2019
Plasmid-mediated horizontal gene transfer (HGT) is a major driver of genetic diversity in bacteria. We experimentally validated the function of a putative mercury resistance operon present on an abundant 8-kbp native plasmid found in groundwater samples ...
Carlson, Hans K, Deutschbauer, Adam M, Kothari, Ankita, Mukhopadhyay, Aindrila, Soneja, Drishti, Tang, Albert   +5 more
core   +1 more source

Microbial monoterpene transformations—a review [PDF]

Frontiers in Microbiology, 2014
Isoprene and monoterpenes constitute a significant fraction of new plant biomass. Emission rates into the atmosphere alone are estimated to be over 500 Tg per year. These natural hydrocarbons are mineralized annually in similar quantities. In the atmosphere, abiotic photochemical processes cause lifetimes of minutes to hours.
Marmulla, R., Harder, J.
openaire   +4 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Intestinal Microecological Mechanisms of Aflatoxin B1 Degradation by Black Soldier Fly Larvae (Hermetia illucens): A Review

Animals
Aflatoxin B1 (AFB1) is a naturally occurring contaminant pervasively found in agricultural produce, exhibiting extremely high carcinogenicity, teratogenicity and immunotoxicity, thereby constituting a substantial menace to worldwide food security and ...
Qiwen Yuan, Jing Xia, Chaorong Ge, Huaiying Yao   +3 more
doaj   +1 more source

Longitudinal transformation of nitrogen and carbon in the hyporheic zone of an N-rich stream: A combined modelling and field study [PDF]

, 2011
A combined modelling and field study approach was used to examine biogeochemical functioning of the hyporheic zone in two gravel bars in an N-rich fourth-order stream (River Hers, south-west France).
Delmotte, Sébastien, Gérino, Magali, Namour, Philippe, Peyrard, Dimitri, Sanchez-Pérez, José Miguel, Simeoni-Sauvage, Sabine, Vervier, Philippe   +6 more
core   +2 more sources

Different carboxyl-rich alicyclic molecules proxy compounds select distinct bacterioplankton for oxidation of dissolved organic matter in the mesopelagic Sargasso Sea [PDF]

, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Liu, S., Parsons, R., Opalk, K., Baetge, N., Giovannoni, S., Bolanos, L. M., Kujawinski, E.
Baetge, Nicholas, Bolaños, Luis M., Carlson, Craig A., Giovannoni, Stephen J., Halewood, Elisa, Kujawinski, Elizabeth B., Liu, Shuting, Longnecker, Krista, Lu, YueHan, Opalk, Keri, Parsons, Rachel J.   +10 more
core   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Interactions between species introduce spurious associations in microbiome studies

, 2018
Microbiota contribute to many dimensions of host phenotype, including disease. To link specific microbes to specific phenotypes, microbiome-wide association studies compare microbial abundances between two groups of samples.
Korolev, Kirill S., Menon, Rajita, Ramanan, Vivek   +2 more
core   +2 more sources