Results 11 to 20 of about 36,678 (116)

Beyond Probiotics: Postbiotics for Healthy Aquaculture

open access: yesAdvanced Science, EarlyView.
This critical review assesses limitations of probiotics and proposes postbiotics, preparations of inanimate microorganisms and their metabolites, as a more stable, controlled, and biosafe formulation. Postbiotics offer significant advantages during industrial aquafeed production and storage. However, their practical implementation is currently hindered
Michael Leonidas Chikindas   +12 more
wiley   +1 more source

Performance Evaluation of the VISITECT CD4 Lateral Flow Point‐Of‐Care Assay for Identifying Advanced HIV Disease

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
The VISITECT CD4 lateral flow assay (LFA) was evaluated for identifying advanced HIV disease (CD4 ≤ 200 cells/μL) during routine programmatic implementation in Argentina. The assay showed 100% sensitivity, while specificity improved after observer training, reflecting reduced reader‐dependent variability.
Mariana Andreani   +7 more
wiley   +1 more source

Ecofriendly management of anthracnose on avocado caused by Colletotrichum perseae in the Mediterranean basin

open access: yesJSFA reports, EarlyView.
Abstract Background Colletotrichum perseae, recently reported in Europe, causes stem and twig lesions and dieback, and fruit rot on avocado in several countries. Due to EU severe restrictions, there is an urgent need for sustainable alternatives to fungicides.
Laura Vecchio   +3 more
wiley   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva   +23 more
wiley   +1 more source

Aspartic Protease Inhibition Induces Proteomic Remodeling in Paracoccidioides brasiliensis

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Paracoccidioidomycosis (PCM) is a major systemic mycosis in Latin America caused by Paracoccidioides brasiliensis, yet the contribution of aspartic proteases to fungal physiology and pathogenicity remains poorly understood. Here, we employed data‐independent acquisition (DIA)‐based quantitative proteomics to investigate the impact of pepstatin
Sarah Fernandes Lima   +6 more
wiley   +1 more source

Reduced fitness cost accounts for the stability of a malathion‐resistant heterogeneous duplication haplotype in Ceratitis capitata field populations

open access: yesPest Management Science, EarlyView.
Malathion resistance in Spanish field populations of Ceratitis capitata is associated with a point mutation (R allele) and a heterogeneous duplication (RS haplotype) of the Ccace2 gene. The R allele imposes a higher fitness cost than the RS haplotype under laboratory and field conditions. An evolutionary model supports the stability of the RS haplotype
Rabeh Arouri   +6 more
wiley   +1 more source

Strain‐specific monitoring of Bacillus amyloliquefaciens AH2 in strawberry fields using a specific molecular marker

open access: yesPest Management Science, EarlyView.
A novel strain‐specific TaqMan quantitative polymerase chain reaction assay targeting the hsdM gene was developed to monitor Bacillus amyloliquefaciens AH2 in strawberries, providing a foundational tool to optimize biocontrol management. Abstract BACKGROUND The biocontrol agent Bacillus amyloliquefaciens AH2 is effective against Botrytis cinerea in ...
M Mercedes Maldonado‐González   +7 more
wiley   +1 more source

Quantification of intestinal bacteria, operating cost and performance of fingerlings Nile tilapia subjected to probiotics

open access: yesLatin American Journal of Aquatic Research, 2015
The use of microorganisms of the genus Bacillus in aquaculture is a nutritional management practice that is rapidly expanding in regions with intensive fish farming.
Nilton Garcia-Marengoni   +1 more
doaj   +1 more source

Piper nigrum Has an Antitumor Effect Through Regulation of the Phosphatidylinositol 3‐Kinase Signaling Pathway in a Murine Model of Acute Myeloid Leukemia

open access: yesPhytotherapy Research, EarlyView.
Overview of the antileukemic effects of Piper nigrum extract in AML. P. nigrum reduced leukemic cell proliferation and glycolytic metabolism through modulation of the PI3K/AKT/mTOR pathway. In vivo, treatment reduced leukemic burden, improved hematological parameters, prolonged survival, and modulated antitumor immune responses.
Natalia Murillo   +3 more
wiley   +1 more source

Microbial Community Dynamics in Marine Water: Influence of Hydrocarbon Type and Exposure Time

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Marine environments are frequently impacted by petroleum‐derived hydrocarbons, which pose ecological risks because of their toxic, mutagenic, and carcinogenic potential. Microorganisms play a crucial role in hydrocarbon degradation, and understanding the influence of time and hydrocarbon type on microbial dynamics helps improve bioremediation ...
Karen C. F. Santaren   +4 more
wiley   +1 more source

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