Results 91 to 100 of about 410,576 (311)

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

CONTRIBUIÇÃO AO ESTUDO DA QUALIDADE MICROBIOLÓGICA E FÍSICO-QUÍMICA DO LEITE UHT

Revista do Instituto de Latícinios Cândido Tostes, 2013
O leite UHT é o leite fluido mais consumido no Brasil. Esse consumo vem crescendo nos últimos anos devido a sua praticidade de armazenamento e longa vida útil.
Ronaldo Tamanini, Vanerli Beloti, José Carlos Ribeiro Júnior, Livia Caveletti Correa da Silva, Alberto Koji Yamada, Francielle de Abreu Silva   +5 more
doaj  

Utilization of microalgae in probiotic white brined cheese

Mljekarstvo, 2022
In this study, the effects of Chlorella vulgaris and Arthrospira platensis fortification on the microbiological, physicochemical and antioxidative properties of probiotic white cheese during storage were investigated.
Gizem Suna, Lutfiye Yilmaz-Ersan
doaj  

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Unveiling the Taxonomic Diversity and Unprecedented Biosynthetic Treasure of the Phylum Myxococcota

Advanced Science, EarlyView.
Natural products remain vital sources of therapeutics, and the phylum Myxococcota constitutes an especially rich reservoir for them. Based on decades of microbiological efforts, we present 154 new Myxococcota genomes and revise taxonomy quadrupling the number of families and genera.
Amay Ajaykumar Agrawal, Ronald Garcia, Guangyi Chen, Chantal D. Bader, Peter Sullivan, Alexander Popoff, Daniel Krug, Maja Hunter, Sebastian Walesch, Emilia Oueis, Christine Frank, Haowen Zhao, Joachim J. Hug, Sebastian Keller, Pascal Hirsch, Azat Tagirdzhanov, Tatiana Malygina, Mary Victory E. Gutierrez, Alexey Gurevich, Judith Boldt, Boyke Bunk, Jörg Overmann, Ulrich Nübel, Andreas Keller, Olga V. Kalinina, Rolf Müller   +25 more
wiley   +1 more source

Microbial and physicochemical assays of paracetamol in different brands of analgesic syrups sold in Sana’a City-Yemen [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2015
Context: Contamination of pharmaceuticals with microorganisms irrespective whether they are harmful or nonpathogenic can bring about changes in physicochemical characteristics of the drugs.
Ali G. Al−Kaf, Saeed M. Alghalibi, Wadhah H. Edrees   +2 more
doaj  

DETERMINATION OF PRIMERS EFFICIENCY IN THE DETECTION OF PEDIOCOCCUS IN WINES

Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2021
Pediococcus spp. are lactic acid bacteria which are considered spoilage in the wine making processes. Early detection can minimize the negative effects of Pediococcus spp on wine quality and prevent the development of advanced spoilage stages.
Alexandra Buga, Irina Mitina, Valentin Mitin, Silvia Rubtov, Dan Zgardan   +4 more
doaj  

Rapid Multiplex Antimicrobial Resistance Profiling and Bacterial Identification by LAP‐MALDI Mass Spectrometry Biotyping

Advanced Science, EarlyView.
Liquid atmospheric pressure matrix‐assisted laser desorption/ionization (LAP‐MALDI) mass spectrometry (MS) provides multiplexed biotyping of microbial cultures using a fast and simple workflow. This is demonstrated for clinically relevant bacteria, resulting in accurate antimicrobial resistance (AMR) detection, speciation by MS/MS sequencing and ...
Lily R. Adair, Shabnam Iyer, Ian M. Jones, Rainer Cramer   +3 more
wiley   +1 more source

Clinical diagnosis and microbiological information.

, 2013
Clinical diagnosis and microbiological information.
Jonathan Edgeworth (471617), Maria Hernandez-Fuentes (350552), Olivier Delfour (392298), Bernard Michot (392307), Yuqian Ma (471614), Marlies Ostermann (471618), Graham M. Lord (471625), David Vilanova (471615), David H. Persing (392305), Kerem Atalar (471616), Per Olcén (471623), Richard Beale (471624), Paula Mölling (471622), Sandrine Razafimahatratra (471619), Ingrid Ziegler (471620), Bianca Törös (471621)   +15 more
core   +1 more source

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

Advanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch, Muhammad D. Ariadi, Min Jung Kwun, Leonie Howells, Saiveth Hernandez‐Hernandez, Nicholas J. Croucher, Pedro J. Ballester   +6 more
wiley   +1 more source