Results 181 to 190 of about 2,361,721 (335)

Integrating Single‐Cell Transcriptome‐Wide Mendelian Randomization and Differentially Expressed Gene Analyses to Prioritize Dynamic Immune‐Related Drug Targets for Cancers

open access: yesAdvanced Science, EarlyView.
Inspired by evidence triangulation, a new sensitivity method called MR‐DEG is developed, which uses the differentially expressed gene (DEG) results as additional evidence to minimize pleiotropic effects and strengthen Mendelian randomization (MR) causal estimates. Using dynamic single‐cell expression quantitative trait loci (eQTLs) as an example, it is
Jie Zheng   +29 more
wiley   +1 more source

EVALUATION OF PHYSICAL-CHEMICAL AND MICROBIOLOGICAL PARAMETERS OF WATER IN SHALLOW WELLS LOCATED IN NEIGHBORHOODS OF PARADISE TOCANTINS

open access: hybrid, 2021
Sérgio Luís Melo Viroli   +4 more
openalex   +1 more source

Collaborative Robot Precision Task in Medical Microbiology Laboratory [PDF]

open access: gold, 2022
Aljaž Baumkircher   +3 more
openalex   +1 more source

Shear Conditioning Promotes Microvascular Endothelial Barrier Resilience in a Human BBB‐on‐a‐Chip Model of Systemic Inflammation Leading to Astrogliosis

open access: yesAdvanced Science, EarlyView.
Physiological flow (0.5 Pa) conditioning promotes resilience of an iPSC‐derived blood–brain barrier endothelium to mild systemic inflammation. In contrast, high “cytokine storm” levels induce barrier breakdown, fibrinogen leakage, and astrocyte activation, reconstituting the two‐hit injury mechanism on‐a‐chip.
Kaihua Chen   +15 more
wiley   +1 more source

Synergistic Promotion of Triple‐Negative Breast Cancer Tumorigenesis and Metastasis by Oral Polystyrene Nanoplastics Exposure via Alloprevotella‐Derived Glutamate and Platelet Activation

open access: yesAdvanced Science, EarlyView.
Polystyrene nanoplastics (PS‐NPs) administered via oral exposure accelerate triple‐negative breast cancer (TNBC) progression by synergistically modulating gut microbiota‐derived glutamate production and platelet activation. This study uncovers a pivotal crosstalk between microbial metabolites and platelet‐tumor interactions, offering mechanistic ...
Leilei Zhu   +9 more
wiley   +1 more source

Faecalibacterium prausnitzii: from microbiology to diagnostics and prognostics

open access: yesThe ISME Journal, 2017
M. López-Siles   +3 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy