Results 211 to 220 of about 2,195,321 (395)

Control of Rhizobia Endosymbiosis by Coupling ER Expansion with Enhanced UPR

open access: yesAdvanced Science, EarlyView.
This study reconstructs legume nodule symbiotic cells using three‐dimensional (3D) scanning electron microscopy (SEM) and uncovers that endoplasmic reticulum (ER) expansion and activation of the unfolded protein response (UPR) are two key events in rhizobia accommodation.
Jing Ren   +8 more
wiley   +1 more source

Observation of Brownian elastohydrodynamic forces acting on confined soft colloids [PDF]

open access: yesarXiv
Confined motions in complex environments are ubiquitous in microbiology. These situations invariably involve the intricate coupling between fluid flow, soft boundaries, surface forces and fluctuations. In the present study, such a coupling is investigated using a novel method combining holographic microscopy and advanced statistical inference ...
arxiv  

Development of MDM2‐Targeting PROTAC for Advancing Bone Regeneration

open access: yesAdvanced Science, EarlyView.
This work presents a creative pipeline for developing MDM2‐targeting PROTACs (MDM2‐PROTACs) for application in bone regeneration. The developed PROTACs (CL144 and CL174) are validated for their degradation efficiency and osteogenic effects in human BMSCs.
Sol Jeong   +17 more
wiley   +1 more source

Clinical microbiology: Should microbiology be a clinical or a laboratory speciality?

open access: yesIndian Journal of Pathology and Microbiology, 2010
Clinical microbiology is a specific combination of knowledge, attitude and practice aimed at direct clinical involvement in infectious disease management using the core principles of medical microbiology and clinical medicine.
Bhattacharya Sanjay
doaj  

Foundations for reconstructing early microbial life [PDF]

open access: yesarXiv
For more than 3.5 billion years, life experienced dramatic environmental extremes on Earth. These include shifts from oxygen-less to over-oxygenated atmospheres and cycling between hothouse conditions and global glaciations. Meanwhile, an ecological revolution took place.
arxiv  

Vitamin Content of Ingredients of Microbiological Culture Media [PDF]

open access: bronze, 1944
J. L. Stokes   +2 more
openalex   +1 more source

Mechanisms of Baicalin Alleviates Intestinal Inflammation: Role of M1 Macrophage Polarization and Lactobacillus amylovorus

open access: yesAdvanced Science, EarlyView.
Baicalin alleviates E. coli‐induced intestinal inflammation through dual mechanisms: direct inhibition of the TLR4/IRF/STAT signaling pathway to modulate macrophage polarization and antigen presentation, thereby regulating Th17/Treg cell differentiation; and microbiota‐mediated indirect effects via increasing Lactobacillus amylovorus abundance and ...
Shunfen Zhang   +10 more
wiley   +1 more source

Decoding Blastocystis‐Driven Mechanisms in Gut Microbiota and Host Metabolism

open access: yesAdvanced Science, EarlyView.
Blastocystis, a prevalent gut microbe, interacts with the host through metabolic and immune pathways, influencing cardiometabolic health. This perspective explores its role in modulating short‐chain fatty acid production, tryptophan metabolism, and immune signaling, potentially impacting cholesterol absorption, glucose metabolism, and vascular health ...
Lei Deng, Kevin SW Tan
wiley   +1 more source

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