Results 121 to 130 of about 376,828 (315)

Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu   +5 more
wiley   +1 more source

Microbiome-Derived Lipid Nanoparticles for Improved Immunogenicity of mRNA Vaccines [PDF]

open access: yes
Lipid nanoparticle (LNP)-based mRNA vaccines have achieved great success during the COVID-19 pandemic. However, the current formulation of LNPs requires additional optimization for the improvement of antigen-specific immunity and the vaccination effect ...
Seok-Beom Yong (17670729)   +2 more
core   +1 more source

Genome plasticity shapes the ecology and evolution of Phocaeicola dorei and Phocaeicola vulgatus

open access: yesScientific Reports
Phocaeicola dorei and Phocaeicola vulgatus are very common and abundant members of the human gut microbiome and play an important role in the infant gut microbiome.
Emilene Da Silva Morais   +4 more
doaj   +1 more source

Comparative analysis of Faecalibacterium prausnitzii genomes shows a high level of genome plasticity and warrants separation into new species-level taxa

open access: yesBMC Genomics, 2018
Background Faecalibacterium prausnitzii is a ubiquitous member of the human gut microbiome, constituting up to 15% of the total bacteria in the human gut. Substantial evidence connects decreased levels of F.
Cormac Brian Fitzgerald   +6 more
doaj   +1 more source

Microbiome yarns: microbiome basis of memory,,, [PDF]

open access: yesMicrobial Biotechnology, 2017
Timmis, Kenneth N.   +4 more
openaire   +6 more sources

The microbiome for clinicians

open access: yesCell
Despite promising evidence in diagnostics and therapeutics, microbiome research is not yet implemented into clinical medicine. Several initiatives, including the standardization of microbiome research, the refinement of microbiome clinical trial design, and the development of communication between microbiome researchers and clinicians, are crucial to ...
Porcari, Serena   +9 more
openaire   +3 more sources

Polychip‐A High‐Throughput Droplet Microfluidics Platform for Interrogating Microbial Interactions

open access: yesAdvanced Science, EarlyView.
Polychip, a fully integrated droplet microfluidics platform, enables high‐throughput, single‐cell resolution screening of polymicrobial interactions. By seamlessly combining six automated microfluidics operations on a single chip, the system accelerates antimicrobial discovery by 11 to 14 times compared to traditional robotic methods.
Jeong Jae Han   +11 more
wiley   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

open access: yesAdvanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li   +7 more
wiley   +1 more source

Temporal stability and lack of variance in microbiome composition and functionality in fit recreational athletes

open access: yesScientific Reports
Human gut microbiome composition and function is influenced by environmental and lifestyle factors, including exercise and fitness. We studied the composition and functionality of the faecal microbiome of recreational (non-elite) runners (n = 62) with ...
Ciara M. O’ Donovan   +6 more
doaj   +1 more source

A bioengineered nisin derivative, M21A, in combination with food grade additives eradicates biofilms of Listeria monocytogenes.

open access: yesFrontiers in Microbiology, 2016
The burden of foodborne disease has large economic and social consequences worldwide. Despite strict regulations, a number of pathogens persist within the food environment, which is greatly contributed to by a build-up of resistance mechanisms and also ...
Lorraine Anne Draper   +6 more
doaj   +1 more source

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