Results 151 to 160 of about 585,088 (321)

Metarhizium anisopliae Mitigates the Phytotoxicity of Lead and Nanoplastics on Rice by Modifying Physiological, Transcriptomic, Metabolomic Activities, and Soil Microbiome

Advanced Science, EarlyView.
Metarhizium anisopliae alleviates the phytotoxic effects of polyethylene nanoplastics (NP) and lead (Pb) in rice by decreasing Pb uptake, restoring antioxidant and hormonal equilibrium, and promoting growth. Additionally, the fungus modifies the rhizosphere microbiota, enhancing both contaminant tolerance and plant growth, thereby effectively ...
Jing Peng, Qi Yan, Muhammad Umair Hassan, Muhammad Imran, Fasih Ullah Haider, Jianfeng Liang, Xingmin Wang, Shaukat Ali   +7 more
wiley   +1 more source

Transcriptomic Insights into Adaptive Strategies of Klebsiella pneumoniae Co-Producing KPC-2 and NDM-5 Carbapenemases Under Meropenem Stress

Infection and Drug Resistance
Liting Dai,1,* Huimin Zhang,1,* Yingyi Cao,1,* Jiacheng Ding,1 Jiaxin Tang,2 Zhirou Xiao,2 Zhemei Chen,2 Jiahui Ling,1 Mengxue Zou,1 Xiwu Cao,1 Lijuan Lin,1 Ziheng Xu,1 Wanting Liu,1 Dingqiang Chen,1 Peibo Yuan1 1Microbiome ...
Dai L, Zhang H, Cao Y, Ding J, Tang J, Xiao Z, Chen Z, Ling J, Zou M, Cao X, Lin L, Xu Z, Liu W, Chen D, Yuan P   +14 more
doaj  

Soil microbiome manipulation and enhanced rock weathering as novel approaches to enhance carbon capture in forest restoration

, 2021
N. Day
openalex   +1 more source

Chemically Engineered L. reuteri Delivering αPD‐L1 and Gallium Ions via Metal‐Phenolic Networks Potentiate Anti‐Tumor Immunity and Ferroptosis

Advanced Science, EarlyView.
A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang, Mengyi Xu, Yan Zhang, Zhiwen Li, Danqing Song, Jing Pang, Ke Li, Yanxiang Wang   +7 more
wiley   +1 more source

Peer Review #1 of "The effect of habitual and experimental antiperspirant and deodorant product use on the armpit microbiome (v0.2)"

, 2016
Julie Urban, Daniel J. Fergus, Amy M. Savage, Megan E Ehlers, Holly Menninger, Robert R. Dunn, Julie E. Horvath, A Benohanian, C Callewaert, P Hutapea, T Van De Wiele, N Boon, C Callewaert, F Kerckhof, M Granitsiotis, M Gele, J Caporaso, J Kuczynski, J Stombaugh, K Bittinger, F Bushman, E Costello, N Fierer, A Pea, J Goodrich, J Gordon, G Huttley, S Kelley, D Knights, J Koenig, R Ley, C Lozupone, D Mcdonald, B Muegge, M Pirrung, J Reeder, J Sevinsky, P Turnbaugh, W Walters, J Widmann, T Yatsunenko, J Zaneveld, R Knight, J Caporaso, C Lauber, E Costello, D Berg-Lyons, A Gonzalez, J Stombaugh, D Knights, P Gajer, J Ravel, N Fierer, J Gordon, N Knight, Gjm Christensen, H Brggemann, K Clarke, Rn ; Primer-E Gorley, P Cohen, E Costello, C Lauber, M Hamady, N Fierer, F Gordon, R Knight, M Egert, I Schmidt, H Hhne, T Lachnit, R Schmitz, R Breves, H Eichenwald, H Shinefield, M Boris, J Ribble, G Flores, J Henley, N Fierer, E Fredrich, H Barzantny, I Brune, A Tauch, Z Gao, G Perez-Perez, Y Chen, M Blaser, E Grice, H Kong, S Conlan, C Deming, J Davis, A Young, Nisc Comparative, Sequencing Program, G Bouffard, R Blakesley, P Murray, E Green, M Turner   +99 more
openalex   +2 more sources

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Plant microbiomes [PDF]

Microbial Biotechnology, 2019
openaire   +3 more sources

Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery

Advanced Science, EarlyView.
Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra, Ibrahim M. Sayed, Souhrid Mukherjee, Honit Piplani, Aida Habtezion, Michael J. Rosen, Jospeh C. Wu   +6 more
wiley   +1 more source

Combining mucosal microbiome and host multi-omics data shows prognostic potential in paediatric ulcerative colitis

Nature Communications
Current first-line treatments of paediatric ulcerative colitis (UC) maintain a 6-month remission in only half of the patients. Relapse prediction at diagnosis could enable earlier introduction of immunosuppressants.
Maria Kulecka, Jill O’Sullivan, Rachel Fitzgerald, Ana Velikonja, Chloe E. Huseyin, Emilio J. Laserna-Mendieta, Patricia Ruiz-Limón, Julia Eckenberger, Miriam Vidal-Marín, Bastian-Alexander Truppel, Raminder Singh, Sandhia Naik, Nicholas M. Croft, Andriy Temko, Aldert Zomer, John MacSharry, Silvia Melgar, Protima Deb, Ian R. Sanderson, Marcus J. Claesson   +19 more
doaj   +1 more source

Faculty Opinions recommendation of Identifying personal microbiomes using metagenomic codes.

, 2015
Elhanan Borenstein, Ohad Manor
openalex   +2 more sources