Results 21 to 30 of about 595,432 (338)

Alpha-synuclein alters the faecal viromes of rats in a gut-initiated model of Parkinson’s disease

Communications Biology, 2021
Stockdale et al. assess longitudinal faecal virome changes in a rat model of Parkinson’s Disease (PD) in which either monomeric or preformed fibrils (PFF) of α-synuclein were administered directly into their enteric nervous system.
Stephen R. Stockdale, Lorraine A. Draper, Sarah M. O’Donovan, Wiley Barton, Orla O’Sullivan, Laura A. Volpicelli-Daley, Aideen M. Sullivan, Cora O’Neill, Colin Hill   +8 more
doaj   +1 more source

Evaluation of the cutaneous microbiome in psoriasis [PDF]

, 2010
Psoriasis, a highly prevalent disease of humans of unknown cause, is a chronic inflammatory disorder primarily involving skin, with distinctive clinical characteristics.
Alexander Alekseyenko, Barbara Methe, Bruce Strober, Guillermo I. Perez Perez, Martin J. Blaser, Stuart Brown   +5 more
core   +2 more sources

The role of bacteria in pine wilt disease: insights from microbiome analysis. [PDF]

, 2018
Pine Wilt Disease (PWD) has a significant impact on Eurasia pine forests. The microbiome of the nematode (the primary cause of the disease), its insect vector, and the host tree may be relevant for the disease mechanism.
Alves, Marta, Correia, A, Henriques, Isabel, Henriques, J, Lopes, H, Matos, P, Mota, Manuel, Nascimento, F, Pereira, A, Vicente, Cláudia   +9 more
core   +1 more source

Rectal Microbiome Composition Correlates with Humoral Immunity to HIV-1 in Vaccinated Rhesus Macaques. [PDF]

, 2019
The microbiome is an integral and dynamic component of the host and is emerging as a critical determinant of immune responses; however, its influence on vaccine immunogenicity is largely not well understood.
Dinasarapu, Ashok R, Durbin-Johnson, Blythe P, Elizaldi, Sonny R, Iyer, Smita S, Kozlowski, Pamela A, Raeman, Reben, Rolston, Matthew, Settles, Matthew, Verma, Anil, Walter, Korey A   +9 more
core   +1 more source

SaQuant: a real-time PCR assay for quantitative assessment of Staphylococcus aureus

BMC Microbiology, 2021
Background Molecular assays are important tools for pathogen detection but need to be periodically re-evaluated with the discovery of additional genetic diversity that may cause assays to exclude target taxa or include non-target taxa.
Colin Wood, Jason Sahl, Sara Maltinsky, Briana Coyne, Benjamin Russakoff, David Panisello Yagüe, Jolene Bowers, Talima Pearson   +7 more
doaj   +1 more source

Synchronous genitourinary lichen sclerosus signals a distinct urinary microbiome profile in men with urethral stricture disease. [PDF]

, 2021
PurposeAlterations in the urinary microbiome have been associated with urological diseases. The microbiome of patients with urethral stricture disease (USD) remains unknown.
Breyer, Benjamin N, Castellanos, Erick R, Cohen, Andrew J, Enriquez, Anthony, Fadrosh, Douglas, Fergus, Kirkpatrick B, Gaither, Thomas W, Lynch, Susan, Mmonu, Nnenaya A, Srirangapatanam, Sudarshan   +9 more
core   +1 more source

Short-term consumption of a high-fat diet increases host susceptibility to Listeria monocytogenes infection

Microbiome, 2019
Background A westernized diet comprising a high caloric intake from animal fats is known to influence the development of pathological inflammatory conditions.
Vanessa Las Heras, Adam G. Clooney, Feargal J. Ryan, Raul Cabrera-Rubio, Pat G. Casey, Cara M. Hueston, Jorge Pinheiro, Justine K. Rudkin, Silvia Melgar, Paul D. Cotter, Colin Hill, Cormac G. M. Gahan   +11 more
doaj   +1 more source

An IBD-associated pathobiont synergises with NSAID to promote colitis which is blocked by NLRP3 inflammasome and Caspase-8 inhibitors

Gut Microbes, 2023
Conflicting evidence exists on the association between consumption of non-steroidal anti-inflammatory drugs (NSAIDs) and symptomatic worsening of inflammatory bowel disease (IBD).
Raminder Singh, Valerio Rossini, Stephen R. Stockdale, Gonzalo Saiz-Gonzalo, Naomi Hanrahan, Tanya D’ Souza, Adam Clooney, Lorraine A. Draper, Colin Hill, Ken Nally, Fergus Shanahan, Stefan Andersson-Engels, Silvia Melgar   +12 more
doaj   +1 more source

Nasal Bacterial Microbiome: Probing a Healthy Porcine Family [PDF]

, 2011
Upper respiratory tract (URT) infection caused the leading and devastating diseases in pigs. It was believed that the normal microbiome of URT plays a vital role in health and disease development.
Huanchun Chen, Min Yue, Weicheng Bei
core   +2 more sources

Isolation and characterisation of ΦcrAss002, a crAss-like phage from the human gut that infects Bacteroides xylanisolvens

Microbiome, 2021
Background The gut phageome comprises a complex phage community of thousands of individual strains, with a few highly abundant bacteriophages. CrAss-like phages, which infect bacteria of the order Bacteroidales, are the most abundant bacteriophage family
Emma Guerin, Andrey N. Shkoporov, Stephen R. Stockdale, Joan Colom Comas, Ekaterina V. Khokhlova, Adam G. Clooney, Karen M. Daly, Lorraine A. Draper, Niamh Stephens, Dimitri Scholz, R. Paul Ross, Colin Hill   +11 more
doaj   +1 more source