Results 41 to 50 of about 463,232 (312)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Identification of robust and generalizable biomarkers for microbiome-based stratification in lifestyle interventions [PDF]

, 2023
Background A growing body of evidence suggests that the gut microbiota is strongly linked to general human health. Microbiome-directed interventions, such as diet and exercise, are acknowledged as a viable and achievable strategy for preventing disorders
Aimin Xu, Siliceo, Sara Leal, Ni, Yueqiong, Henrik B. Nielsen, Ni, YQ, Jiarui Chen, Panagiotou, Gianni, Xu, AM, Panagiotou, G, Siliceo, SL, Chen, JR, Yueqiong Ni, Gianni Panagiotou, Chen, Jiarui, Xu, Aimin, Sara Leal Siliceo, Nielsen, Henrik B., Nielsen, HB   +17 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Human Microbiome [PDF]

Global Advances in Health and Medicine, 2014
In 2011, at the Society for Integrative Oncology's international meeting in Cleveland, Ohio, Francis Collins, PhD, head of the National Institutes of Health, shocked the audience when he asserted that although his work in the human genome was exciting, he was more impressed by the potential represented by the National Institutes of Health's investment ...
Plotnikoff, Gregory A., Riley, David
openaire   +2 more sources

Microbiome ethics, guiding principles for microbiome research, use and knowledge management [PDF]

, 2022
International audienceAbstract The overarching biological impact of microbiomes on their hosts, and more generally their environment, reflects the co-evolution of a mutualistic symbiosis, generating fitness for both.
Makhalanyane, Thulani P., Makhalanyane, Thulani, Sanz Herranz, Yolanda, Annelein Meisner, Makhalanyane, Thulani Peter, Maguin, Emmanuelle, Marie-Christine Champornier-Vergès, Charles, Trevor, Hauke Smidt, Yolanda Sanz, de Souza, Rafael Soares, Angela Sessitsch, Luca Cocolin, Lange, Lene, Wakelin, Steve, Champomier‑Vergès, Marie‑Christine, Cernava, Tomislav, de Souza, Rafael S., Gabriele Berg, Cotter, Paul, Kiran, George Seghal, Tanja Kostic, D’hondt, Kathleen, Lene Lange, Champomier-Vergès, Marie-Christine, George Seghal Kiran, Matthew Ryan, Berg, Gabriele, Michael Schloter, Kostic, Tanja, Cocolin, Luca, Schloter, Michael, Steve Wakelin, Sessitsch, Angela, de Souza, Rafael Soares Correa, Smidt, Hauke, Paul Cotter, Meisner, Annelein, Ryan, Matthew, Emmanuelle Maguin, Kathleen D´Hondt, Thulani Makhalanyane, Kiran, George S., Sanz, Yolanda, D'Hondt, Kathleen, Rafael Soares de Souza   +45 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Characterizing microbiome changes in the graduate student gut [PDF]

, 2016
Dysbiosis of the human microbiome is linked to human health problems, and as such, is a main concern of anthropological microbiome research. Analysis of how microbiomes change over time and under stress may reveal trends that lead to dysbiotic states ...
Lund, Justin
core  

Skin microbiome modulation induced by probiotic solutions

, 2019
Background: The skin is colonized by a large number of microorganisms, most of which are beneficial or harmless. However, disease states of skin have specific microbiome compositions that are different from those of healthy skin.
Pereira de Lima, Joao, Brüggemann, Holger, Paetzold, Bernhard, 1981-, Knödlseder, Nastassia, Willis, Jesse R., Quist, Sven Roy, Gabaldón Estevan, Juan Antonio, 1973-, Güell Cargol, Marc, 1982-   +7 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

The plant microbiome [PDF]

Genome Biology, 2013
Plant genomes contribute to the structure and function of the plant microbiome, a key determinant of plant health and productivity. High-throughput technologies are revealing interactions between these complex communities and their hosts in unprecedented detail.
Turner, T, James, E, Poole, P
openaire   +3 more sources