Results 51 to 60 of about 463,232 (312)

Influence of diet on the gut microbiome and implications for human health

Journal of Translational Medicine, 2017
Recent studies have suggested that the intestinal microbiome plays an important role in modulating risk of several chronic diseases, including inflammatory bowel disease, obesity, type 2 diabetes, cardiovascular disease, and cancer.
Rasnik K. Singh, H. Chang, Di Yan, Kristina M. Lee, D. Uçmak, Kirsten Wong, M. Abrouk, B. Farahnik, Mio Nakamura, T. Zhu, T. Bhutani, W. Liao   +11 more
semanticscholar   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Microbiome and Gluten [PDF]

Annals of Nutrition and Metabolism, 2015
Celiac disease (CD) is a frequent chronic inflammatory enteropathy caused by gluten in genetically predisposed individuals that carry disease susceptibility genes (HLA-DQ2/8). These genes are present in about 30-40% of the general population, but only a small percentage of carriers develops CD.
openaire   +2 more sources

Lactobacillus, glycans and drivers of health in the vaginal microbiome

, 2022
A microbiome consists of microbes and their genomes, encompassing bacteria, viruses, fungi, protozoa, archaea, and eukaryotes. These elements interact dynamically in the specific environment in which they reside and evolve. In the past decade, studies of
Barrangou, Rodolphe, Sanozky-Dawes, Rosemary   +1 more
core  

Human Gut Bacteria and Lipidic Nanoparticles: Particle Composition Predicts Structural Transformation and Bacterial Biocompatibility

Advanced Functional Materials, EarlyView.
Lipidic nanoparticles (LNPs) were incubated with 21 gut bacteria frequently associated with the human microbiome. SAXS revealed that ∼75% of tested species induced structural transformations in monoolein LNPs, whereas phytantriol and phospholipid formulations remained unaffected.
Jonathan Caukwell, Emily L. Gulliver, Livia Salvati Manni, Frithjof Herb, Caitlin Welsh, Samuel C. Forster, Andrew J. Clulow, Wye‐Khay Fong   +7 more
wiley   +1 more source

Lung microbiome: new insights into the pathogenesis of respiratory diseases

Signal Transduction and Targeted Therapy
The lungs were long thought to be sterile until technical advances uncovered the presence of the lung microbial community. The microbiome of healthy lungs is mainly derived from the upper respiratory tract (URT) microbiome but also has its own ...
Ruomeng Li, Jing Li, Xikun Zhou
semanticscholar   +1 more source

Specialized metabolic functions of keystone taxa sustain soil microbiome stability

Microbiome, 2021
The relationship between biodiversity and soil microbiome stability remains poorly understood. Here, we investigated the impacts of bacterial phylogenetic diversity on the functional traits and the stability of the soil microbiome.
Weibing Xun, Yunpeng Liu, Wei Li, Yi Ren, Wu Xiong, Zhihui Xu, N. Zhang, Youzhi Miao, Q. Shen, Ruifu Zhang   +9 more
semanticscholar   +1 more source

The fecal microbiome in dogs with acute diarrhea and idiopathic inflammatory bowel disease. [PDF]

, 2012
Recent molecular studies have revealed a highly complex bacterial assembly in the canine intestinal tract. There is mounting evidence that microbes play an important role in the pathogenesis of acute and chronic enteropathies of dogs, including ...
Toresson, Linda, Jörg M. Steiner (107366), Ivan Ivanov, Dillman, Enricka M., Enricka M Dillman, Ivanov, Ivan, Stefan Unterer (107353), Heimesaat, Markus M., García Mazcorro, José Francisco, Jan S. Suchodolski (107343), Romy M Heilmann, Markel, Melissa E., Enricka M. Dillman (107363), Linda Toresson (107370), Melissa E Markel, Markel, Melissa, Linda Toresson, Steiner, J��rg M., Audrey K. Cook (107368), Cook, Audrey K., Jan S Suchodolski, Minamoto, Yasushi, Jörg M Steiner, Garcia-Mazcorro, Jose F., Priyanka Kachroo, Scot E. Dowd (107356), Heilmann, Romy M., Dowd, Scot E., Yasushi Minamoto, Jose F. Garcia-Mazcorro (107351), Unterer, Stefan, Romy M. Heilmann (107355), Jose F Garcia-Mazcorro, Stefan Unterer, Yasushi Minamoto (107360), Scot E Dowd, Audrey K Cook, Ivan Ivanov (107359), Melissa E. Markel (107347), Priyanka Kachroo (107357), Kachroo, Priyanka, Steiner, Jörg M., Suchodolski, Jan S.   +42 more
core   +1 more source

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

Advanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino, Lucia Pappagallo, Francesca De Chirico, Luca Boselli, Hazem Ahmed, Luca Spagnoletti, Giovanni Pittaluga, Paolo Emidio Costantini, Matteo Calvaresi, Pier Paolo Pompa, Alberto Danielli, Fabio Benfenati, Valentina Castagnola   +12 more
wiley   +1 more source

Oral Microbiome: A Review of Its Impact on Oral and Systemic Health

Microorganisms
Purpose of review: This review investigates the oral microbiome’s composition, functions, influencing factors, connections to oral and systemic diseases, and personalized oral care strategies.
J. Rajasekaran, H. Krishnamurthy, Jophi Bosco, Vasanth Jayaraman, K. Krishna, Tianhao Wang, K. Bei   +6 more
semanticscholar   +1 more source