Results 71 to 80 of about 463,232 (312)
Advanced Science, EarlyView.ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao +11 more
wiley +1 more source
Asthma Research and Practice, 2018 The mucosal immune system is in constant communication with the vast diversity of microbes present on body surfaces. The discovery of novel molecular mechanisms, which mediate host-microbe communication, have highlighted the important roles played by microbes in influencing mucosal immune responses. Dendritic cells, epithelial cells, ILCs, T regulatory
Sokolowska, Milena +4 more
openaire +4 more sources
Advanced Science, EarlyView.This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia +5 more
wiley +1 more source
, 2022 The prevalence of overweight and obesity has reached epidemic proportions globally over the past few decades. The search for new management approaches continues and among them, targeting the gut microbiota can be envisioned. To date, numerous data showed the involvement of the gut microbes in the regulation and control of host metabolism.
Delzenne, Nathalie M., Rodriguez, Julie
openaire +3 more sources
Nature Reviews Cancer, 2019 Collectively known as the microbiota, the commensal bacteria and other microorganisms that colonize the epithelial surfaces of our body have been shown to produce small molecules and metabolites that have both local and systemic effects on cancer onset, progression and therapy response.
Eran Elinav +3 more
openaire +2 more sources
A unified catalog of 204,938 reference genomes from the human gut microbiome
Nature Biotechnology, 2020 Comprehensive, high-quality reference genomes are required for functional characterization and taxonomic assignment of the human gut microbiota. We present the Unified Human Gastrointestinal Genome (UHGG) collection, comprising 204,938 nonredundant ...
Alexandre Almeida +12 more
semanticscholar +1 more source
Factors Affecting the Gut Microbiome
, 2017 The recent boom in microbiome research, made possible by advances in sequencing technology, has revealed that the gut microbiome plays an important role in human health.
Lamoureux, Emily
core
Advanced Science, EarlyView.A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min +6 more
wiley +1 more source
Temporal development of the gut microbiome in early childhood from the TEDDY study
Nature, 2018 The development of the microbiome from infancy to childhood is dependent on a range of factors, with microbial–immune crosstalk during this time thought to be involved in the pathobiology of later life diseases1–9 such as persistent islet autoimmunity ...
C. Stewart +25 more
semanticscholar +1 more source
Airway Microbiome; Allergy, Asthma
, 2016 The rate at which the prevalence of allergy keeps rising globally poses a threat to health and economic development.Various parts of the immune system are involved in this process and some delineated genetic and environmental factors seem to contribute ...
Bashir, Maryam
core