Results 171 to 180 of about 574,054 (312)

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

Advanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan, Qiu Dai, Yanhui Wang, Jiaxuan Gu, Chengyun Wang, Weicheng Xu, Xinru Gao, Jiageng Cheng, Wentao Geng, Xiaowen Wu, Haihang Li, Xiaoyun He, Shengwei Fu, Longjiao Zhu, Wentao Xu   +14 more
wiley   +1 more source

Functional Abdominal Bloating and Gut Microbiota: An Update

(1) Background: Functional abdominal bloating and distension (FAB/FAD) are common disorders of the gut–brain interaction. Their physiopathology is complex and not completely clarified, although gut microbiota imbalances play a central role.
Federico Caldart, Andrea Costantino, Marco Michelon, Salvatore Crucillà, Giovanni Marasco   +4 more
core   +1 more source

Reducing Antibiotic Drug Use Effects on Clostridioides difficile Colonization in Nursing Home Residents¹. [PDF]

Emerg Infect Dis
Reeves M, Mangalea MR, Gowler CD, Paul P, Wolford H, Lutgring JD, Reddy SC, Halpin AL, McDonald LC, Slayton RB.   +9 more
europepmc   +1 more source

Gut Microbial Topology and Metabolic Signatures Associated With Colorectal Neoplasia

Advanced Science, EarlyView.
The gut microbiota organizes into two robust association patterns linked to colorectal neoplasia risk. Topological shifts in microbial networks are associated with metabolite alterations and may shape host responses during disease development. ABSTRACT Alterations of gut microbial communities impact health.
Kai Song, Youwen Qin, Jiahui Luo, Liping Liu, Chenyu Luo, Yinbin Qiu, Yiyi Zhong, Huanzi Zhong, Kui Wu, Meng Ni, Dong Wu, Min Dai, Shida Zhu, Hongda Chen   +13 more
wiley   +1 more source

Fecal Microbiota Transplantation: A Promising Therapeutic Strategy Targeting the Microbiota-Gut-Brain Axis in Anorexia Nervosa. [PDF]

Brain Behav
Kwok SL, Xiao YC, Cai XB.
europepmc   +1 more source

Omnidirectional Interaction Networks Modulating Phenotypic Plasticity in the Gut Microbiota Towards Ulcerative Colitis

Advanced Science, EarlyView.
This study employs a spouse‐pair cohort design and an idopNetwork model that integrates evolutionary game theory, predator‐prey dynamics, and developmental modularity theory to reconstruct maximally informative microbial interaction networks. This approach reveals how interspecies interactions drive the phenotypic plasticity of the gut microbiota in ...
Huizhen Li, Jiayi Li, Ang Dong, Xiaoyan Guo, Qiuyue Tu, Zelin Feng, Haojia Lin, Yanru Zhang, Yuxuan Hao, Huiying Gong, Yihan Meng, Yu Wang, Shing‐Tung Yau, Xiaocang Cao, Rongling Wu, Xinjuan Liu   +15 more
wiley   +1 more source

Single‐Nucleus Transcriptomic Atlas of Human Vellus Hair Pilosebaceous Units Reveals Age‐Associated Remodeling

Advanced Science, EarlyView.
Human vellus pilosebaceous units (PSUs) remain uncharted. This single‐nucleus atlas reveals coordinated remodeling of the aging PSU niche: reduced bulge stem cell representation with altered regenerative programs, increased representation of a stress‐responsive channel+ epithelial state, enhanced androgen‐responsive sebaceous programs, reduced ...
Ya'nan Li, Zhuoqiong Qiu, Xiaoyu Pan, Geyang Xu, Shanshan Peng, Ronghui Zhu, Qiuyang Luo, Xiaokai Fang, Xu Yao, Wei Li   +9 more
wiley   +1 more source

Research Advances and Perspectives on Gut Microbiota Regulating Alzheimer's Disease. [PDF]

Biology (Basel)
Zhu F, Shao X.
europepmc   +1 more source

The Potential of Self‐Maintainable Living Materials

Advanced Science, EarlyView.
Self‐maintainable living materials are presented as the next generation of bioadaptive systems, integrating continuous sensing, decision‐making, response, self‐repair, and adaptation in a closed‐loop framework. This review highlights the design principles and emerging technologies that enable autonomous, long‐term functionality for future regenerative ...
Mohammadsadegh Nadimifar, Tatiane Eufrásio‐da‐Silva, Lidia Maeso, Gorka Orive, Alireza Dolatshahi‐Pirouz   +4 more
wiley   +1 more source

Host Phylogeny Shapes Gut Microbiota and Predicted Functions in Captive Artiodactyls

Host phylogeny can imprint the gut microbiota, but it is often masked by diet and environment. Leveraging the standardized husbandry of a zoological collection, we profiled fecal microbiota from 55 captive artiodactyls representing 12 species in Bovidae,
Xibao Wang, Guolei Sun, Qinguo Wei, Xiufeng Yang, Honghai Zhang, Tian Xia, Lei Zhang, Weilai Sha, Yuehuan Dong   +8 more
core   +1 more source