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[Intestinal microbiota]. [PDF]

Aten Primaria, 2016
The human body normally lives in symbiosis with a considerable microscopic environment present on all interfaces with the external environment; it hosts ten times more microbes (microbiota) that it has somatic or germ cells, representing a gene diversity (microbiome) 100-150 times higher than the human genome. These germs are located mainly in the gut,
Serra J.
europepmc   +7 more sources

Effect of Bacteriocins on the Intestinal Microbiota

Eurasian Journal of Medicine, 2023
Intestinal microbiota, which plays an important role in human health by interacting with each other or with its hosts, is afected by many endogenous and exogenous factors.
Selin Dogan, Taha Yasin Koc, Mehmet Karadayi   +2 more
doaj   +4 more sources

Application of Dominant Gut Microbiota Promises to Replace Fecal Microbiota Transplantation as a New Treatment for Alzheimer’s Disease [PDF]

Microorganisms, 2023
Several studies have confirmed that the pathophysiological progression of Alzheimer’s disease (AD) is closely related to changes in the intestinal microbiota; thus, modifying the intestinal microbiota has emerged as a new way to treat AD.
Mufan Li, Huan Yang, Chenyi Shao, Yinhui Liu, Shu Wen, Li Tang   +5 more
doaj   +2 more sources

Role of the Spore Coat Proteins CotA and CotB, and the Spore Surface Protein CDIF630_02480, on the Surface Distribution of Exosporium Proteins in Clostridioides difficile 630 Spores

Microorganisms, 2022
Clostridioides difficile is Gram-positive spore-former bacterium and the leading cause of nosocomial antibiotic-associated diarrhea. During disease, C. difficile forms metabolically dormant spores that persist in the host and contribute to recurrence of ...
Nicolás Montes-Bravo, Alba Romero-Rodríguez, José García-Yunge, César Medina, Marjorie Pizarro-Guajardo, Daniel Paredes-Sabja   +5 more
doaj   +1 more source

Respiratory Heme A-Containing Oxidases Originated in the Ancestors of Iron-Oxidizing Bacteria

Frontiers in Microbiology, 2021
Respiration is a major trait shaping the biology of many environments. Cytochrome oxidase containing heme A (COX) is a common terminal oxidase in aerobic bacteria and is the only one in mammalian mitochondria. The synthesis of heme A is catalyzed by heme
Mauro Degli Esposti, Ana Moya-Beltrán, Ana Moya-Beltrán, Raquel Quatrini, Raquel Quatrini, Raquel Quatrini, Lars Hederstedt   +6 more
doaj   +1 more source

Analysis of colonic mucosa-associated microbiota using endoscopically collected lavage

Scientific Reports, 2022
The bacterial composition of the gut lumen and mucosa is distinct and the mucosa-associated bacteria are thought to play a more critical role in interactions with the host immune system.
Eiji Miyauchi, Takashi Taida, Masami Kawasumi, Toshifumi Ohkusa, Nobuhiro Sato, Hiroshi Ohno   +5 more
doaj   +1 more source

Characterization of Exosporium Layer Variability of Clostridioides difficile Spores in the Epidemically Relevant Strain R20291

Frontiers in Microbiology, 2020
Clostridioides difficile is a Gram-positive anaerobic intestinal pathogenic bacterium and the causative agent of antibiotic-associated diarrhea. C. difficile spore is a dormant state which acts as a vehicle of transmission and infection. In C.
Marjorie Pizarro-Guajardo, Marjorie Pizarro-Guajardo, Paulina Calderón-Romero, Alba Romero-Rodríguez, Alba Romero-Rodríguez, Daniel Paredes-Sabja, Daniel Paredes-Sabja   +6 more
doaj   +1 more source

Updating changes in human gut microbial communities associated with Clostridioides difficile infection

Gut Microbes, 2021
Clostridioides difficile is the causative agent of antibiotic-associated diarrhea, a worldwide public health problem. Different factors can promote the progression of C.
Giovanny Herrera, Daniel Paredes-Sabja, Manuel Alfonso Patarroyo, Juan David Ramírez, Marina Muñoz   +4 more
doaj   +1 more source

The effectiveness and safety of vedolizumab induction for moderate to severe ulcerative colitis for Asia patient: A real practice observational study

Journal of the Formosan Medical Association, 2022
Background: The use of biologic agents has become the cornerstone of therapy for moderate to severe IBD. Few studies have investigated the efficacy of vedolizumab (VDZ) induction for ulcerative colitis (UC) in Asian patients in a real practice setting ...
Chia-Jung Kuo, Puo-Hsien Le, Wei-Chen Tai, Keng-Liang Wu, Hsu-Heng Yen, Chih-Wei Yen, Shui-Yi Tung, Chen-Shuan Chung, Ming-Yao Su, Cheng-Tang Chiu   +9 more
doaj   +1 more source

The chaperone ClpC participates in sporulation, motility, biofilm, and toxin production of Clostridioides difficile

Journal of Global Antimicrobial Resistance, 2023
: Objectives: Clostridioides difficile is a nosocomial pathogen that is associated with the use of antibiotics. One of the most worrying aspects of C. difficile infection is its ability to resist antimicrobial therapies, owing to spore formation.
Camila Queraltó, Constanza Ortega, Fernando Díaz-Yáñez, Osvaldo Inostroza, Giovanni Espinoza, Ricardo Álvarez, Ruth González, Francisco Parra, Daniel Paredes-Sabja, Lillian G. Acuña, Iván L. Calderón, Juan A. Fuentes, Fernando Gil   +12 more
doaj   +1 more source