Results 51 to 60 of about 6,931 (237)

Production of functionally active Penicillium chrysogenum isopenicillin N synthase in the yeast Hansenula polymorpha

BMC Biotechnology, 2008
Background β-Lactams like penicillin and cephalosporin are among the oldest known antibiotics used against bacterial infections. Industrially, penicillin is produced by the filamentous fungus Penicillium chrysogenum.
Veenhuis Marten, van der Klei Ida J, Klaassen Paul, Bovenberg Roel AL, Gidijala Loknath, Kiel Jan AKW   +5 more
doaj   +1 more source

Fossilization of melanosomes via sulfurization [PDF]

, 2016
Fossil melanin granules (melanosomes) are an important resource for inferring the evolutionary history of colour and its functions in animals. The taphonomy of melanin and melanosomes, however, is incompletely understood.
Bull, Ian D, Lockyer, Nick P, McNamara, Maria E, Orr, Patrick J, Van Dongen, Bart E   +4 more
core   +3 more sources

Purification, morphometric analysis, and characterization of the glycosomes (microbodies) of the protozoan hemoflagellate Trypanosoma brucei

Journal of Cell Biology, 1984
Trypanosoma brucei glycosomes (microbodies containing nine enzymes involved in glycolysis) have been purified to near homogeneity from bloodstream-form trypomastigotes for the purpose of morphologic and biochemical analysis.
P. Baudhuin, C. Roe, S. Edwards, P. Weijers   +3 more
semanticscholar   +1 more source

Hepatotrophic effects of FK506 in dogs [PDF]

, 1991
Portacaval shunt (Eck fistula) in dogs causes hepato- cyte atrophy and organelle disruption, as well as tripling of hepatocyte mitoses. After submitting dogs to this pro-cedure, FK506 was infused into the tied-off left portal vein.
Francavilla, A, Fung, J, Mazzaferro, V, Porter, KA, Starzl, TE, Todo, S   +5 more
core   +1 more source

Discocelia Plataet Sp. n., a Small Incertae Sedis Cercozoan Flagellate

Journal of Eukaryotic Microbiology, Volume 72, Issue 5, September/October 2025.
ABSTRACT Cercozoa = Filosa (Rhizaria, SAR) is one of the largest rhizarian subgroups and consists of a diverse assemblage of amoeboid and flagellated protists. They are ecologically significant in microbial food webs, widely diverse, and even abundant in soils and deep marine sediments according to environmental sequencing.
Kristina Prokina, Guifré Torruella, Luis Javier Galindo, Omaya Dudin, Purificación López‐García, David Moreira   +5 more
wiley   +1 more source

Cryo‐SEM and large volume FIB‐SEM of Arabidopsis cotyledons: Degradation of lipid bodies, biogenesis of glyoxysomes and reorganisation of organelles during germination

Journal of Microscopy, Volume 299, Issue 3, Page 242-267, September 2025.
Abstract Until recently, the lack of three‐dimensional visualisation of whole cells at the electron microscopic (EM) level has led to a significant gap in our understanding of the interaction of cellular organelles and their interconnection. This is particularly true with regard to the role of the endoplasmic reticulum (ER).
Gerhard Wanner, Elizabeth Schroeder‐Reiter, Farhah F. Assaad   +2 more
wiley   +1 more source

Streamline Protocol for Arabidopsis Apoplastic Fluid Isolation Enables a Detailed Proteomic View of the Plant Extracellular Space

Plant Direct, Volume 9, Issue 7, July 2025.
ABSTRACT The apoplastic space surrounding plant cells, encompassing the cell wall matrix, extracellular spaces, and xylem, is one of the least understood compartments within plant tissues due to its lack of limiting membranes and its unavoidable damage upon tissue homogenization. Using a streamlined vacuum‐infiltration/centrifugation protocol to enrich
Kuo‐En Chen, Marilee Karinshak, Richard D. Vierstra   +2 more
wiley   +1 more source

V‐ATPases and amino acid catabolism are strongly disturbed in the roots of autophagy mutants in Arabidopsis, impacting water use efficiency and tricarboxylic acid metabolism

The Plant Journal, Volume 123, Issue 2, July 2025.
Significance Statement This study reveals that V‐ATPases were less abundant in the roots of autophagy mutants than in wild type. This V‐ATPases deficit, associated with lower root water contents and lower nitrate, magnesium, and potassium concentrations, indicates that disturbance of cellular ion and water management in autophagy mutants was likely ...
Maxence James, Jacques Trouverie, Benoit Bernay, Anne Marmagne, Fabien Chardon, Marin‐Pierre Gemin, Philippe Etienne, Céline Masclaux‐Daubresse   +7 more
wiley   +1 more source

Comparative Transcriptomic Analysis of AtBBX29 Transgenic and Wild Type Sugarcane Exposed to Drought Stress

Physiologia Plantarum, Volume 177, Issue 3, May/June 2025.
ABSTRACT Previously, we produced drought‐tolerant transgenic sugarcane plants that overexpressed the AtBBX29 gene, which encodes a transcription factor (TF) B‐box protein. These plants displayed delayed senescence, were able to maintain photosynthesis, and accumulated high levels of antioxidants and osmolytes when exposed to water deficit stress ...
Christell van der Vyver, Preetom Regon, Kristen Fulton, Sanjib K. Panda   +3 more
wiley   +1 more source

Cobalt Single‐Atom Intercalation in Molybdenum Disulfide Enhances Piezocatalytic and Enzyodynamic Activities for Advanced Cancer Therapeutics

Advanced Science, Volume 12, Issue 14, April 10, 2025.
The single‐atom doped molybdenum disulfide piezocatalyst markedly enhances both piezoelectric and enzyme‐mimicking activities, accelerating glutathione depletion. It induces mitochondrial dysfunction and cell cycle arrest, ultimately driving apoptosis while inactivating glutathione peroxidase 4 to initiate ferroptosis.
Haomiao Bai, Sujun Ding, Yanfei Dai, Jiefu Liu, Huangjing Chen, Wei Feng, Dehong Yu, Yu Chen, Xuejun Ni   +8 more
wiley   +1 more source