Results 31 to 40 of about 26,182 (249)

Effect of Pulse Shaping on Subharmonic Aided Pressure Estimation In Vitro and In Vivo. [PDF]

open access: yes, 2016
OBJECTIVES: Subharmonic imaging (SHI) is a technique that uses the nonlinear oscillations of microbubbles when exposed to ultrasound at high pressures transmitting at the fundamental frequency ie, f METHODS: Eight waveforms with different envelopes were ...
Dave, Jaydev K.   +11 more
core   +2 more sources

Cavitation Characterization of Size-Isolated Microbubbles in a Vessel Phantom Using Focused Ultrasound

open access: yesPharmaceutics, 2022
Pharmaceutical delivery can be noninvasively targeted on-demand by microbubble (MB) assisted focused ultrasound (FUS). Passive cavitation detection (PCD) has become a useful method to obtain real-time feedback on MB activity due to a FUS pulse.
Payton Martinez   +2 more
doaj   +1 more source

Focused ultrasound-enabled brain tumor liquid biopsy [PDF]

open access: yes, 2018
Although blood-based liquid biopsies have emerged as a promising non-invasive method to detect biomarkers in various cancers, limited progress has been made for brain tumors.
Chen, Hong   +10 more
core   +3 more sources

Ultrasound-induced microbubble coalescence [PDF]

open access: yesUltrasound in Medicine & Biology, 2004
We studied the interaction of ultrasound contrast agent bubbles coated with a layer of lipids, driven by 0.5 MHz ultrasound. High-speed photography on the submicrosecond timescale reveals that some bubbles bounce off each other, while others show very fast coalescence during bubble expansion.
Postema, Michiel   +4 more
openaire   +5 more sources

Polymer Mechanochemistry in Microbubbles

open access: yesAdvanced Materials, 2023
AbstractPolymer mechanochemistry is a promising technology to convert mechanical energy into chemical functionality by breaking covalent and supramolecular bonds site‐selectively. Yet, the mechanochemical reaction rates of covalent bonds in typically used ultrasonication setups lead to reasonable conversions only after comparably long sonication times.
Mingjun Xuan   +10 more
openaire   +3 more sources

Fundamentals and Applications of Focused Ultrasound-Assisted Cancer Immune Checkpoint Inhibition for Solid Tumors

open access: yesPharmaceutics
Despite spectacular clinical successes across several cancer types, immune checkpoint inhibition is effective only in subgroups of patients and suffers from significant systemic toxicities, highlighting the need to understand and locally overcome the ...
Sepideh Jahangiri, François Yu
doaj   +1 more source

Reversal of aging-induced increases in aortic stiffness by targeting cytoskeletal protein-protein interfaces [PDF]

open access: yes, 2018
BACKGROUND: The proximal aorta normally functions as a critical shock absorber that protects small downstream vessels from damage by pressure and flow pulsatility generated by the heart during systole.
Chiu, Joanna   +10 more
core   +1 more source

Methods for Rapid Characterization of Tunable Microbubble Formulations

open access: yesBioengineering
To optimize microbubble formulations for clinical applications, the size distribution, concentration, and acoustic intensity must be rapidly measurable to allow for the successful iteration of microbubble design. In this paper, a comprehensive method was
Savannah L. Harpster   +2 more
doaj   +1 more source

Microbubble formulation influences inflammatory response to focused ultrasound exposure in the brain

open access: yesScientific Reports, 2020
Focused ultrasound and microbubble (FUS + MB)-mediated blood–brain barrier (BBB) permeability enhancement can facilitate targeted brain-drug delivery.
Dallan McMahon   +4 more
doaj   +1 more source

Effects of Ultrasound Targeted Destruction of Echogenic Nanobubbles Containing Doxorubicin in Rat Liver

open access: yesJournal of Surgical Ultrasound, 2023
Ultrasound is a widely used diagnostic medical imaging modality, and its therapeutic potential has recently been reported. This study examined whether ultrasound irradiation causes nanobubble destruction and identified the most effective frequency and ...
Jung Hyun Park, Il Young Park
doaj   +1 more source

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