Results 121 to 130 of about 197,951 (371)

The UW solution for canine kidney preservation: Its specific effect on renal hemodynamics and microvasculature [PDF]

, 1989
The preservation effects of UW solution on renal hemodynamics and microvascular systems were studied in canine kidney autografts. In 72-hr UW-preserved kidneys, the microvessels of both cortex and medulla were completely visualized with silicon rubber ...
Furukawa, H, Imventarza, O, Oguma, S, Oks, A, Starzl, TE, Todo, S, Ueda, Y, Wu, YM   +7 more
core   +1 more source

Mild psoriasis as a suitable model for proof‐of‐mechanism in a phase 1B setting: Results from a double‐blind placebo‐controlled trial with guselkumab

British Journal of Clinical Pharmacology, EarlyView.
Aims Early clinical development of novel psoriasis therapies is hampered by a decreasing number of moderate‐to‐severe psoriasis patients eligible for participation in trials since efficacious treatments, such as biologics, have become widely available.
Jannik Rousel, Menthe E. Bergmans, Lisa J. Bruijnincx, Sissi Lin, Tessa Niemeyer‐van der Kolk, Roman Bohoslavsky, Yalçin Yavuz, Naomi B. Klarenbeek, Joke A. Bouwstra, Robert Rissmann, Martijn B. A. van Doorn, the Next‐Generation ImmunoDermatology Consortium (NGID)   +11 more
wiley   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Transcriptome Analysis Revealed Inflammation Is Involved in the Impairment of Human Umbilical Vein Endothelial Cells Induced by Post-hemorrhagic Shock Mesenteric Lymph

Frontiers in Immunology, 2020
Vascular endothelial injury caused by post-hemorrhagic shock mesenteric lymph (PHSML) return is an important manifestation during refractory hemorrhagic shock.
Qi Wang, Qi Wang, Zhen-Fen Chi, Di Wei, Zhen-Ao Zhao, Zhen-Ao Zhao, Hong Zhang, Hong Zhang, Li-Min Zhang, Li-Min Zhang, Yan-Xu Liu, Yan-Xu Liu, An-Ling Kang, An-Ling Kang, Meng Zhao, Meng Zhao, Peng Wang, Peng Wang, Ling-Hu Nie, Chun-Yu Niu, Chun-Yu Niu, Zi-Gang Zhao, Zi-Gang Zhao, Zi-Gang Zhao   +23 more
doaj   +1 more source

Photoacoustic imaging for microcirculation

Microcirculation, 2022
Shubham Mirg, Kevin L. Turner, Haoyang Chen, Patrick J. Drew, Sri-Rajasekhar Kothapalli   +4 more
semanticscholar   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Endothelial β-catenin upregulation and Y142 phosphorylation drive diabetic angiogenesis via upregulating KDR/HDAC9

Cell Communication and Signaling
Background Diabetic angiogenesis is closely associated with disabilities and death caused by diabetic microvascular complications. Advanced glycation end products (AGEs) are abnormally accumulated in diabetic patients and are a key pathogenic factor for ...
Zhenfeng Chen, Bingqi Lin, Xiaodan Yao, Jie Weng, Jinlian Liu, Qi He, Ke Song, Chuyu Zhou, Zirui Zuo, Xiaoxia Huang, Zhuanhua Liu, Qiaobing Huang, Qiulin Xu, Xiaohua Guo   +13 more
doaj   +1 more source

Effect of hypokinesia on blood microcirculation [PDF]

Blood microcirculation in the region of the scleral bulbar conjunctiva and the nail folds on the fingers and toes was studied in 18 practically healthy men during 182 day antiorthostatic hypokinesia and 30 day rehabilitation period.
Aleksandrov, P. N., Chernukh, A. M., Fedorov, B. M., Gazenko, O. G., Krupina, T. N., Proskurina, T. N., Ranferova, N. Y., Shagal, D. I.   +7 more
core   +1 more source

Impaired healing following implant placement surgery: A case report of a modern‐day manifestation of scurvy

Clinical Advances in Periodontics, EarlyView.
Abstract Background Delayed wound healing following implant placement surgery is an uncommon complication, usually attributed to systemic (smoking and alcohol), local (severely inflamed tissues), or technical (poor suturing) factors. However, delayed wound healing after implant placement caused by severe hypovitaminosis C has not been previously ...
Gregor‐Georg Zafiropoulos, Gerald Kolb, Dimitris N. Tatakis   +2 more
wiley   +1 more source

Periodontitis and metabolic diseases (diabetes and obesity): Tackling multimorbidity

Periodontology 2000, EarlyView., 2023
Abstract Noncommunicable diseases (NCDs) are multifactorial, long‐term, chronic conditions that represent a burden to health‐care systems worldwide as they can only be controlled rather than cured; hence, they require long‐term care. With the exponential increase in NCDs, the occurrence of individuals presenting with more than one chronic disease is ...
Crystal Marruganti, Jean E. Suvan, Francesco D'Aiuto   +2 more
wiley   +1 more source