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Adsorption of an Amine Drug onto Microcrystalline Cellulose and Silicified Microcrystalline Cellulose Samples

Drug Development and Industrial Pharmacy, 2003
The adsorption of a model amine drug (tacrine hydrochloride) from aqueous solution onto 21 microcrystalline cellulose (MCC) based samples has been investigated. The MCC source (manufacturer) affected adsorption. The adsorption appeared to be fully reversible.
D Fraser, Steele   +4 more
openaire   +2 more sources

Is Silicified Wet-Granulated Microcrystalline Cellulose Better than Original Wet-Granulated Microcrystalline Cellulose?

Pharmaceutical Development and Technology, 1999
The purpose of this study was to investigate the effect of granulating water level on the physical-mechanical properties of microcrystalline cellulose (MCC) and silicified microcrystalline cellulose (SMCC). Granulations containing either MCC or SMCC were manufactured at different water levels using a high-shear mixer and were then tray-dried. The water
Y S, Habib   +4 more
openaire   +2 more sources

Microcrystalline cellulose in tableting

Journal of Pharmaceutical Sciences, 1966
The development of microcrystalline cellulose has made available to the pharmaceutical industry an extremely valuable tableting agent. It was found that tablets of plain microcrystalline cellulose will tend to soften and swell when exposed to humid conditions, but the effect is reversed upon the removal of increased humidities.
Dongyue Yu   +2 more
openaire   +2 more sources

Physicochemical comparison between microcrystalline cellulose and silicified microcrystalline cellulose

International Journal of Pharmaceutics, 1998
Abstract Silicified microcrystalline cellulose (SMCC) has been compared with a standard grade of microcrystalline cellulose (MCC) using several physicochemical techniques in order to elucidate any chemical or polymorphic changes in the material that could be attributed to the silicification process.
openaire   +1 more source

Microcrystalline Cellulose (MCC or Cellulose Gel)

2022
Microcrystalline cellulose (MCC) is one of the few relatively new ingredients available to the food industry. The manufacturing process most common to microcrystalline cellulose produced two divergent products. The first type of product is powdered microcrystalline cellulose.
openaire   +1 more source

True Density of Microcrystalline Cellulose

Journal of Pharmaceutical Sciences, 2005
Microcrystalline cellulose (MCC) exhibits unusual tableting properties, sometimes, inconsistent with its high plasticity. It is found that some of the unusual tableting properties of MCC can be explained in part by the use of inaccurate true density during tableting data analysis.
openaire   +2 more sources

Thin-layer chromatography on microcrystalline cellulose

Journal of Chromatography A, 1965
Abstract “Avirin”, or “Avicel”, a microcyrstalline form of cellulose, has been with success in this laboratory for thin-layer chromatography. The material is employed without a binder and has, in this laboratory, essentially completely displaced the papergram because its speed, quality of separation, and the ease with which preparative plates may be ...
M L, WOLFROM   +2 more
openaire   +2 more sources

Properties of starch-based aerogels incorporated with agar or microcrystalline cellulose

, 2020
In this work, starch-based aerogels incorporated with agar or microcrystalline cellulose (MCC) were obtained via thermal gelation in aqueous media, retrogradation, solvent exchange using ethanol, and supercritical drying with carbon dioxide (CO2).
M. Dogenski   +3 more
semanticscholar   +1 more source

Rheology of Microcrystalline Cellulose-Carboxymethylcellulose Gels

Journal of Pharmaceutical Sciences, 1968
Rheological evaluations of MCC-CMC gels were employed to delineate their properties. It was concluded that the thixotropic nature of MCC-CMC gels depended upon the adsorption of the soluble CMC on the MCC. A certain degree of shear was required to unsheave the microcrystals. However, excessive shear reduced the degree of structuring.
W D, Walkling, R F, Shangraw
openaire   +2 more sources

Directional Bonding in Compacted Microcrystalline Cellulose

Drug Development and Industrial Pharmacy, 2001
The mechanical properties of compacts of microcrystalline cellulose (MCC) and silicified microcrystalline cellulose (SMCC) were evaluated by tensile testing, diametric compression testing, and compression testing. For tensile and compression testing, cubic specimens were carefully machined from MCC and SMCC compacts, and the tensile and compression ...
S, Edge   +4 more
openaire   +2 more sources

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