Results 51 to 60 of about 11,204 (224)

Regulation of Microcystin-LR-Induced DNA Damage by miR-451a in HL7702 Cells

Toxins, 2019
Microcystin-LR is a cyclic heptapeptide hepatotoxin produced by harmful cyanobacteria. A panel of microRNAs containing miR-451a were found to be significantly changed in normal human liver cells HL7702 after exposure to microcystin-LR (MC-LR) in our ...
Lv Chen, Shu Yang, Cong Wen, Shuilin Zheng, Yue Yang, Xiangling Feng, Jihua Chen, Dan Luo, Ran Liu, Fei Yang   +9 more
doaj   +1 more source

Nuclear Dbf2-related protein kinases (NDRs) in isolated cardiac myocytes and the myocardium: activation by cellular stresses and by phosphoprotein serine-/threonine-phosphatase inhibitors [PDF]

, 2008
The nuclear Dbf2-related protein kinases 1 and 2 (NDR1/2) are closely-related AGC family kinases that are strongly conserved through evolution. In mammals, they are activated inter alia by phosphorylation of an hydrophobic domain threonine-residue [NDR1 ...
Clerk, Angela, Cornils, H, Cullingford, Timothy E., Fuller, Stephen John, Hemmings, B. A., Hergovitch, A, Molkentin, Jeff D., Pikkarainen, Sampsa, Sugden, Peter H., Tham, El Li   +9 more
core   +1 more source

Fear of grazing rivals the toxin‐inducing effects of nutrients in two marine harmful algae – a meta‐analysis

Biological Reviews, EarlyView.
ABSTRACT One of the major subfields of chemical ecology is the study of toxins and how they mediate interactions between organisms. Toxins produced by harmful algae (phycotoxins) impact a wide variety of organisms connected to the marine food web. Significant research efforts have thus aimed to identify the ecological and evolutionary drivers behind ...
Milad Pourdanandeh, Erik Selander
wiley   +1 more source

Migration pattern of silver eel (Anguilla anguilla, L.) in an obstructed river system. [PDF]

, 2008
The downstream migration of European silver eels in the River Frémur was examined to determine the potential effects of the numerous migration barriers that exist on waterways in western France.
Acou, Acou, Acou, Acou, Acou, Acou, Baisez, Behrmann-Godel, Berg, Boubée, Boubée, Boëtius, Budy, Chadwick, Congleton, Cullen, Deelder, Durif, Durif, Durif, Escofier, Euston, Feunteun, Feunteun, Feunteun, Feunteun, Ficke, Frost, Gosset, Hansen, Haraldstad, Haro, Haro, Holmgren, Hvidsten, Jonsson, Laffaille, Larinier, Lee, Legault, Lobon-Cervia, Lowe, Naismith, Olivereau, Pankhurst, Plumb, Robinet, Ryan, Schmidt, Sokal, Tesch, Todd, Travade, van den Thillart, van Ginneken, van Ginneken, van Ginneken, Vøllestad, Vøllestad, Watene, White, Wickström, Zaugg   +62 more
core   +2 more sources

Cyanopeptide Mixtures Induce Variable Synergistic and Antagonistic Effects Across Diverse Human Cell Lines

Environmental Toxicology, EarlyView.
ABSTRACT Cyanobacterial harmful algal blooms (cyanoHABs) threaten human, animal, and ecosystem health and safety through production of toxic secondary metabolites. Microcystis, a cosmopolitan bloom‐forming cyanobacterial genus, is well‐known for producing hepatotoxic microcystins (MCs), but it can produce many other bioactive cyanopeptides, such as ...
Lauren N. Hart, Katherine L. Lev, Sierra Hefferan, Sanduni H. Premathilaka, Sharmila I. Thenuwara, Dragan Isailovic, David H. Sherman, Gregory J. Dick   +7 more
wiley   +1 more source

Fabrication of graphene film composite electrochemical biosensor as a pre-screening algal toxin detection tool in the event of water contamination

Scientific Reports, 2018
In this work, we fabricated a novel graphene film composite biosensor for microcystin-LR detection as an alternative to time-consuming, expensive, non-portable and often skills-demanding conventional methods of analysis involved in water quality ...
Wei Zhang, Baoping Jia, Hiroaki Furumai
doaj   +1 more source

Dog Poisonings Associated with a Microcystis aeruginosa Bloom in the Netherlands

Toxins, 2013
In early autumn 2011, three dogs died after they had been exposed to a Microcystis aeruginosa bloom on Lake Amstelmeer, The Netherlands. The cyanobacterial scum from the lake contained up to 5.27 × 103 μg g−1 dry-weight microcystin, the vomit of one of ...
Miquel Lürling, Elisabeth J. Faassen
doaj   +1 more source

Sub-chronic exposure to waterborne extracellular microcystin-LR impairs calcium homeostasis in rainbow trout

Ecotoxicology and Environmental Safety, 2023
Fish mortality is associated with harmful algal blooms, although whether toxicity is related directly to the presence of cyanotoxins or the prevailing water chemistry remains unclear.
Diane A. Mielewczyk, Chris N. Glover, Chantelle E. Klaczek, Greg G. Goss, Gavin N. Saari   +4 more
doaj   +1 more source

Do Cyanobacteria Blooms Enhance Parasite Loads in Lake Erie Yellow Perch? [PDF]

, 2020
Harmful Algal Blooms composed of cyanobacteria (HABs) are a major concern globally, especially in ecosystems that support commercial and recreational fisheries. Although HABs have been shown to negatively affect the services provided by ecosystems (e.g.,
Rude, Brady
core  

Synergistic and Antagonistic Effects of Chemical Pollutants and Parasitic Fungi on Cyanobacterial Metabolism

Environmental Toxicology, EarlyView.
ABSTRACT Freshwater ecosystems are increasingly impacted by anthropogenic pollutants, including the widely used herbicide metolachlor (MET) and cigarette butt (CB) litter. Parasites represent an additional biotic stressor that can modulate pollutant effects on their hosts.
Erika Berenice Martínez‐Ruiz, Jutta Fastner, Stephanie Spahr, Justyna Wolinska   +3 more
wiley   +1 more source