Results 71 to 80 of about 11,204 (224)

Measurement of Microcystin Activity in Human Plasma Using Immunocapture and Protein Phosphatase Inhibition Assay

Toxins, 2022
Microcystins are toxic chemicals generated by certain freshwater cyanobacteria. These chemicals can accumulate to dangerous levels during harmful algal blooms.
Brady R. Cunningham, Rebekah E. Wharton, Christine Lee, Mike A. Mojica, Logan C. Krajewski, Shirley C. Gordon, Adam M. Schaefer, Rudolph C. Johnson, Elizabeth I. Hamelin   +8 more
doaj   +1 more source

Multiomic single nuclei profiling the mouse hippocampus reveals that ACSS2 confers neuronal resilience to tauopathy

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Epigenomic dysregulation contributes to Alzheimer's disease (AD) and related tauopathies. Acetyl‐CoA synthetase 2 (ACSS2), a nuclear‐localized metabolic enzyme in neurons, supports histone acetylation and learning‐related gene expression.
Gabor Egervari, Desi C. Alexander, Hua Huang, Greg Donahue, Connor Hogan, Mariel Mendoza, Hong Xu, Virginia Lee, Ben Garcia, Nancy Bonini, Shelley Berger   +10 more
wiley   +1 more source

Diversity of microcystin-producing genotypes in Brazilian strains of Microcystis (Cyanobacteria)

Brazilian Journal of Biology
Microcystis Kützing ex Lemmermann is among the genera of cyanobacteria often associated to toxic blooms with the release of microcystins. A gene cluster codes for microcystin synthetases, which are involved in the biosynthesis of this toxin.
MC Bittencourt-Oliveira, MC Oliveira, E Pinto   +2 more
doaj   +1 more source

Influencing factors and health risk assessment of microcystins in the Yongjiang river (China) by Monte Carlo simulation [PDF]

PeerJ, 2018
The Yongjiang river is a large, shallow, hyper-trophic, freshwater river in Guangxi, China. To investigate the presence of microcystin-RR, microcystin-LR, and microcystin-YR (MC-RR, MC-LR, and MC-YR) in the Yongjiang river and describe their correlation ...
Chan-Chan Xiao, Mao-Jian Chen, Fan-Biao Mei, Xiang Fang, Tian-Ren Huang, Ji-Lin Li, Wei Deng, Yuan-Dong Li   +7 more
doaj   +2 more sources

Cellular transport of microcystin-LR in rainbow trout (Oncorhynchus mykiss) across the intestinal wall: possible involvement of multidrug resistance-associated proteins [PDF]

, 2014
We studied Abcc mediated-transport in middle and posterior intestine of the rainbow trout, Oncorhynchus mykiss. Luminal and serosal transport were evaluated in everted and non-everted intestinal sacs, respectively, incubated with 1-chloro-2,4 ...
Bieczynski, Flavia, Brena, Beatriz M., de Anna, Julieta Soledad, Luquet, Carlos Marcelo, Pirez, Macarena, Villanueva, Silvina Stella Maris   +5 more
core   +1 more source

Protective Effect and Mechanism of Rosiglitazone in α‐amanitin‐induced Hepatotoxicity Via Activation of PPAR‐γ/Nrf2 Signaling Pathway

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 2, February 2026.
ABSTRACT α‐amanitin (α‐AMA), the primary lethal toxin of amanita, primarily targets the liver with a high toxicity and a low lethal dose. As the precise mechanism of intoxication is unclear, and specific antidotes are lacking, α‐AMA‐induced liver injury has a high mortality rate.
Fuping Lai, Ya Liao, Jin Wu, Tinggang Wang, Guiyi Zhang, Xiaojun Zhang, Caiyun Xia, Jie Hu, Yuanlan Lu   +8 more
wiley   +1 more source

Probiotic Protects Kidneys Exposed to Microcystin-LR

Translation
Cyanobacterial Harmful Algal Blooms (CyanoHABs) occur when colonies of photosynthetic bacteria called cyanobacteria grow out of control, usually in warm, nutrient-rich, slow-moving waters.
Yolanda Hu, Irene Sun, Eric Tang, William Ryan, Upasana Shrestha, Jyotshana Gautam, Apurva Lad, Jason F. Huntley, Steven Haller, David Kennedy   +9 more
doaj   +3 more sources

First Detection of Microcystin-LR in the Amazon River at the Drinking Water Treatment Plant of the Municipality of Macapá, Brazil

Toxins, 2019
Human poisoning by microcystin has been recorded in many countries, including Brazil, where fatal cases have already occurred. The Amazon River is the main source of drinking water in municipalities such as Macapá, where there is no monitoring of ...
Elane D.C. Oliveira, Raquel Castelo-Branco, Luis Silva, Natalina Silva, Joana Azevedo, Vitor Vasconcelos, Silvia Faustino, Alan Cunha   +7 more
doaj   +1 more source

New Zealand Guidelines for cyanobacteria in recreational fresh waters: Interim Guidelines [PDF]

, 2009
This document is divided into four main sections, plus 14 appendices. Section 1. Introduction provides an overview of the purpose and status of the document as well as advice on who should use it. Section 2.
Hamilton, David P., Paul, Wendy J., Safi, Karl A., Williamson, Wendy M., Wood, Susanna A.   +4 more
core   +1 more source

Study of cyanotoxin degradation and evaluation of their transformation products in surface waters by LC-QTOF MS [PDF]

, 2019
In the present work, the degradation of three cyanotoxins from the hepatotoxins group was investigated under laboratory-controlled experiments in water samples.
Beltrán Iturat, Eduardo, Boix Sales, Clara, Hernandez, Felix, León, Cristina, Lopez, Francisco, Peñuela, Gustavo, Sancho, Juan V   +6 more
core   +2 more sources