Results 81 to 90 of about 11,325 (225)

Multiomic single nuclei profiling the mouse hippocampus reveals that ACSS2 confers neuronal resilience to tauopathy

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Epigenomic dysregulation contributes to Alzheimer's disease (AD) and related tauopathies. Acetyl‐CoA synthetase 2 (ACSS2), a nuclear‐localized metabolic enzyme in neurons, supports histone acetylation and learning‐related gene expression.
Gabor Egervari, Desi C. Alexander, Hua Huang, Greg Donahue, Connor Hogan, Mariel Mendoza, Hong Xu, Virginia Lee, Ben Garcia, Nancy Bonini, Shelley Berger   +10 more
wiley   +1 more source

Microcystins in components of twelve New Hampshire lakes of varied trophic status [PDF]

, 1999
Cyanobacteria toxins, called microcystins (MCs), were found in components of twelve, stratified New Hampshire (USA) lakes of varied trophic status during the summer of 1998.
Johnson, Kimberly M.
core   +1 more source

Microcystin-LR in surface water of Ponjavica river

Vojnosanitetski pregled, 2012
Background/Aim. Cyanobacterial toxins befall a group of various compounds according to chemical structure and health effects on people and animals. The most significant in this large group of compounds are microcystins. Their presence in water used for human consumption causes serious health problems, liver beeing the target organ ...
Dejan Natic, Dragana Jovanovic, Tanja Knezevic, Vesna Karadzic, Zorica Bulat, Vesna Matovic   +5 more
openaire   +4 more sources

Mitochondria a key role in microcystin‐LR kidney intoxication [PDF]

Journal of Applied Toxicology, 2007
AbstractMicrocystins (MCs) are a group of closely related cyclic heptapeptides produced by a variety of common cyanobacteria. These toxins have been implicated in both human and livestock mortality. Microcystin‐LR could affect renal physiology by altering vascular, glomerular and urinary parameters, indicating that MC‐LR could act directly on the ...
La-Salete, R., Oliveira, M. M., Palmeira, C. A., Almeida, J., Peixoto, F. P.   +4 more
openaire   +3 more sources

Protective Effect and Mechanism of Rosiglitazone in α‐amanitin‐induced Hepatotoxicity Via Activation of PPAR‐γ/Nrf2 Signaling Pathway

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 2, February 2026.
ABSTRACT α‐amanitin (α‐AMA), the primary lethal toxin of amanita, primarily targets the liver with a high toxicity and a low lethal dose. As the precise mechanism of intoxication is unclear, and specific antidotes are lacking, α‐AMA‐induced liver injury has a high mortality rate.
Fuping Lai, Ya Liao, Jin Wu, Tinggang Wang, Guiyi Zhang, Xiaojun Zhang, Caiyun Xia, Jie Hu, Yuanlan Lu   +8 more
wiley   +1 more source

Probiotic Protects Kidneys Exposed to Microcystin-LR

Translation
Cyanobacterial Harmful Algal Blooms (CyanoHABs) occur when colonies of photosynthetic bacteria called cyanobacteria grow out of control, usually in warm, nutrient-rich, slow-moving waters.
Yolanda Hu, Irene Sun, Eric Tang, William Ryan, Upasana Shrestha, Jyotshana Gautam, Apurva Lad, Jason F. Huntley, Steven Haller, David Kennedy   +9 more
doaj   +3 more sources

Noncompetitive Chromogenic Lateral-Flow Immunoassay for Simultaneous Detection of Microcystins and Nodularin

Biosensors, 2019
Cyanobacterial blooms cause local and global health issues by contaminating surface waters. Microcystins and nodularins are cyclic cyanobacterial peptide toxins comprising numerous natural variants.
Sultana Akter, Teemu Kustila, Janne Leivo, Gangatharan Muralitharan, Markus Vehniäinen, Urpo Lamminmäki   +5 more
doaj   +1 more source

New Zealand Guidelines for cyanobacteria in recreational fresh waters: Interim Guidelines [PDF]

, 2009
This document is divided into four main sections, plus 14 appendices. Section 1. Introduction provides an overview of the purpose and status of the document as well as advice on who should use it. Section 2.
Hamilton, David P., Paul, Wendy J., Safi, Karl A., Williamson, Wendy M., Wood, Susanna A.   +4 more
core   +1 more source

Migration pattern of silver eel (Anguilla anguilla, L.) in an obstructed river system. [PDF]

, 2008
The downstream migration of European silver eels in the River Frémur was examined to determine the potential effects of the numerous migration barriers that exist on waterways in western France.
Acou, Acou, Acou, Acou, Acou, Acou, Baisez, Behrmann-Godel, Berg, Boubée, Boubée, Boëtius, Budy, Chadwick, Congleton, Cullen, Deelder, Durif, Durif, Durif, Escofier, Euston, Feunteun, Feunteun, Feunteun, Feunteun, Ficke, Frost, Gosset, Hansen, Haraldstad, Haro, Haro, Holmgren, Hvidsten, Jonsson, Laffaille, Larinier, Lee, Legault, Lobon-Cervia, Lowe, Naismith, Olivereau, Pankhurst, Plumb, Robinet, Ryan, Schmidt, Sokal, Tesch, Todd, Travade, van den Thillart, van Ginneken, van Ginneken, van Ginneken, Vøllestad, Vøllestad, Watene, White, Wickström, Zaugg   +62 more
core   +3 more sources

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

Advanced Science, Volume 13, Issue 2, 9 January 2026.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen, Ahlem Meziadi, Cyrill Brunner, Maureen McKeague, Lidija Malic, Maryam Tabrizian   +5 more
wiley   +1 more source