Results 101 to 110 of about 107,595 (212)

Activation of Nrf2 by Microcystin-LR Provides Advantages for Liver Cancer Cell Growth

, 2010
Microcystin-LR (MC-LR) is a potent heptapeptide hepatotoxin at high doses, but its underlying mechanism of promoting liver cell proliferation at low doses is unclear.
Song, LR, CAS, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China, Sun, Xiaoyun, Gan, Nanqin, Song, Lirong   +3 more
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Responses of antioxidant systems in the hepatocytes of common carp (Cyprinus carpio L.) to the toxicity of microcystin-LR

, 2003
The freshwater, bloom-forming cyanobacterium (blue-green alga) Microcystis aeruginosa produces a peptide hepatotoxin, which causes the damage of animal liver.
Yongding Liu, Xiaoyu Li, Jiantong Liu, Lirong Song, Liu, YD, Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Hubei, Peoples R China   +4 more
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Gene expression profiles in liver of zebrafish treated with microcystin-LR

, 2008
Microcystin-LR (MC-LR) is the most frequently studied cyclic heptatoxin produced by cyanobacteria, which has tremendous negative impacts on fish, while its molecular mechanism behind remained unclear at present.
Nie, P, Chinese Acad Sci, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China, Sun, Baojian, Nie, Pin, Wei, Lili, Song, Lirong   +4 more
core   +1 more source

Microcystin-LR induces aberrant expression of microRNAs in the liver of whitefish.

, 2016
Changes in 9 selected miRNAs expression (log fold change) assessed using qPCR (left panel) and miRNA-Seq method (right panel) in control (blue squares) and microcystin-LR-treated (100 μg MC-LR kg-1 body weight; red triangles) whitefish. Point markings in
Paweł Brzuzan (3155694), Alicja Łakomiak (3155691), Maciej Florczyk (3155697), Maciej Woźny (3155688)   +3 more
core   +1 more source

Two New Strains of Microcystis Cyanobacteria from Lake Baikal, Russia: Ecology and Toxigenic Potential

Limnological Review
Microcystis, a potentially toxigenic cyanobacterium known to form extensive blooms in eutrophic lakes globally, was investigated in the cold oligotrophic Lake Baikal.
Ekaterina Sorokovikova, Irina Tikhonova, Galina Fedorova, Nadezhda Chebunina, Anton Kuzmin, Maria Suslova, Yanzhima Naidanova, Sergey Potapov, Andrey Krasnopeev, Anna Gladkikh, Olga Belykh   +10 more
doaj   +1 more source

Optimization and Modeling of Microcystin-LR Degradation by TiO2 Photocatalyst Using Response Surface Methodology

Journal of Environmental Health and Sustainable Development, 2020
Introduction: Microcystin-leucine arginine (MC-LR) is a toxin with harmful effects on the liver, kidney, heart, and gastrointestinal tract. So, effective removal of MC-LR from water resources is of great importance.
Negar Jafari, Afshin Ebrahimi, Karim Ebrahimpour, Ali Abdolahnejad   +3 more
doaj  

Development of a highly sensitive inhibition immunoassay for microcystin-LR

, 2004
The development of a rapid one-step antigen-immobilized inhibition ELBA for microcystin-LR is described. For microplate coating a microcystin-biotin conjugate was synthesized.
Wolf, Hans, Yacoub-George, Erwin, Dürkop, Axel, Lindner, Petra, Molz, Ramona   +4 more
core   +1 more source

Microcystin-LR induces histopathological injury and cell apoptosis in the hepatopancreas of white shrimp, Litopenaeus vannamei

Ecotoxicology and Environmental Safety
Microcystin-LR (MC-LR), a common hepatotoxin produced by bloom-forming cyanobacteria, presents a serious threat to the health of aquatic animals.
Zhao Chen, Haiqing Yuan, Shuangyong Zhang, SM Sharifuzzaman, Zhiqiang Chang   +4 more
doaj   +1 more source

Laboratory studies of dissolved radiolabelled microcystin-LR in lake water

, 2003
The fate of dissolved microcystin-LR was studied in laboratory experiments using surface water taken from a eutrophic lake. Based on initial range finding, a concentration of 50 microg l(-1) dissolved 14C-microcystin-LR was selected for subsequent time ...
Hyenstrand, Per, Thomas Rohrlack, Rohrlack, Thomas, Christoffersen, Kirsten, Codd, Geoffrey A, James S. Metcalf, Geoffrey A. Codd, Kenneth A. Beattie, Metcalf, James S, Beattie, Kenneth A, Per Hyenstrand, Kirsten Christoffersen   +11 more
core   +1 more source

Establishment of cell model for the study of cytotoxicity induced by microcystin-LR

, 2006
Microcystins are a group of closely related cyclic heptapeptides produced by a variety of common cyanobacteria. These toxins cause hepatocyte damage by inhibiting protein phosphastases I and 2A, resulting in hyperphosphorylation of a number of different ...
Lei La-Mei, Song Li-Rong (lrsong@ihb.ac.cn), Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol and Biotechnol, Wuhan 430072, Peoples R China   +2 more
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