Results 41 to 50 of about 23,887 (275)

High Levels of Structural Diversity Observed in Microcystins from Microcystis CAWBG11 and Characterization of Six New Microcystin Congeners

Marine Drugs, 2014
Microcystins (MCs) are cyclic peptides produced by cyanobacteria, which can be harmful to humans and animals when ingested. Differences in the coding of the non‑ribosomal peptide synthetase/polyketide synthase enzyme complex responsible for microcystin ...
Jonathan Puddick, Michèle R. Prinsep, Susanna A. Wood, Sangata A. F. Kaufononga, Stephen Craig Cary, David P. Hamilton   +5 more
doaj   +1 more source

A Comparative Review of the Effect of Microcystin-LR on the Proteome

Exposure and Health, 2019
Cyanobacterial toxins are a growing threat to human and animal welfare in many parts of the world. Microcystin-LR is the most widely studied of the cyanotoxins and has been implicated with hepatotoxicity, neuropathology, and genotoxicity.
Richard D. Welten, Julie P. Meneely, C. Elliott   +2 more
semanticscholar   +1 more source

Evidence of the cost of the production of microcystins by Microcystis aeruginosa under differing light and nitrate environmental conditions. [PDF]

PLoS ONE, 2012
The cyanobacterium Microcystis aeruginosa is known to proliferate in freshwater ecosystems and to produce microcystins. It is now well established that much of the variability of bloom toxicity is due to differences in the relative proportions of ...
Enora Briand, Myriam Bormans, Catherine Quiblier, Marie-José Salençon, Jean-François Humbert   +4 more
doaj   +1 more source

Contrasting histories of microcystin-producing cyanobacteria in two temperate lakes as inferred from quantitative sediment DNA analyses

Lake and reservoir management, 2019
Pilon S, Zastepa A, Taranu ZE, Gregory-Eaves I, Racine M, Blais JM, Poulain AJ, Pick FR. 2018. Contrasting histories of microcystin-producing cyanobacteria in two temperate lakes as inferred from quantitative sediment DNA analyses. Lake Reserv Manage. 35:
Shinjini Pilon, A. Zastepa, Z. Taranu, I. Gregory‐Eaves, Marianne Racine, J. Blais, Alexandre J. Poulain, F. Pick   +7 more
semanticscholar   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

Effects of Dietary Astaxanthin Supplementation on Energy Budget and Bioaccumulation in Procambarus clarkii (Girard, 1852) Crayfish under Microcystin-LR Stress

Toxins, 2018
This research aimed to study the effects of astaxanthin on energy budget and bioaccumulation of microcystin-leucine-arginine (microcystin-LR) in the crayfish Procambarus clarkii (Girard, 1852).
Zhenhua An, Yingying Zhang, Longshen Sun
doaj   +1 more source

The Biosynthesis of Rare Homo-Amino Acid Containing Variants of Microcystin by a Benthic Cyanobacterium

Marine Drugs, 2019
Microcystins are a family of chemically diverse hepatotoxins produced by distantly related cyanobacteria and are potent inhibitors of eukaryotic protein phosphatases 1 and 2A.
T. K. Shishido, J. Jokela, Anu Humisto, Suvi Suurnäkki, M. Wahlsten, D. Alvarenga, K. Sivonen, D. Fewer   +7 more
semanticscholar   +1 more source

Algal Blooms in Lakes Increase After Wildfire Smoke Events in the Contiguous United States

Global Change Biology Communications, EarlyView.
Temporary pulses of surface chlorophyll‐a are identified following wildfire smoke events in lakes and reservoirs across the United States. ABSTRACT Area burned by wildfire has increased in the contiguous United States and in many places globally in recent years, impacting communities and ecosystems nearby and even far downwind of fires. We examined the
Nicole E. Olson, Meredith M. Brehob, Robert D. Sabo, Irena Pavlovic, Kathleen I. Shank, Sam Penry, Amalia M. Handler, Michael J. Pennino, R. Byron Rice, Katie L. Boaggio, Stephen D. LeDuc   +10 more
wiley   +1 more source

Microcystin-LR incorporated into colonic cells through probenecid-sensitive transporters leads to upregulated MCP-1 expression induced by JNK activation

Toxicology Reports, 2022
Harmful algae that inhabit eutrophic lakes produce cyanotoxic microcystins. Therefore, the relationship between chronic exposure to microcystins via drinking water and organ disorders has been investigated.
Yoshihito Koto, Hideaki Kawahara, Koichi Kurata, Keisuke Yoshikiyo, Ayumi Hashiguchi, Kunihiro Okano, Norio Sugiura, Kazuya Shimizu, Hidehisa Shimizu   +8 more
doaj   +1 more source

Nanomaterials' Multigenerational Effects by Single and Joint Exposure in Non‐mammalian Models

Environmental Toxicology, EarlyView.
ABSTRACT Nanotoxicology has mainly focused on single‐generation studies, leaving multigenerational toxicity underexplored. Having animal welfare recently gained importance, we aimed to provide the state‐of‐the‐art of knowledge about multigenerational effects in non‐mammalian models in the case of nanomaterials (NM) single and joint exposure to other ...
Andy Joel Taipe Huisa, Analía Ale, Azael Francisco Silva Neto, Lorena De Mendonça Lucena, Marcelo Estrella Josende, Milena Ferreira de Lima, Rhayanny Kethylly Pereira Santos, Martín Federico Desimone, Priscila Gubert, José María Monserrat   +9 more
wiley   +1 more source