Results 51 to 60 of about 13,733 (224)

Effects of different doses of microcystin-LR exposure on gut development and the microbiota of Xenopus laevis tadpoles

BMC Microbiology
Background Although the acute toxicity of microcystin-LR has been widely confirmed, its effects on aquatic organisms at environmental concentrations have not been systematically studied.
Jinjin Li, Yuanyuan Zhang, Jiajia Ni, Wenxuan Hou, Lei Huang, Hanping Pan, Chenxu Wang, Kaixin Wang, Shaoyuan Zuo, Jiahao Dong, Mingyu Zhang   +10 more
doaj   +1 more source

Selectivity and potency of microcystin congeners against OATP1B1 and OATP1B3 expressing cancer cells. [PDF]

PLoS ONE, 2014
Microcystins are potent phosphatase inhibitors and cellular toxins. They require active transport by OATP1B1 and OATP1B3 transporters for uptake into human cells, and the high expression of these transporters in the liver accounts for their selective ...
Timo H J Niedermeyer, Abigail Daily, Monika Swiatecka-Hagenbruch, Jeffrey A Moscow   +3 more
doaj   +1 more source

Microcystin-LR incorporated into colonic cells through probenecid-sensitive transporters leads to upregulated MCP-1 expression induced by JNK activation

Toxicology Reports, 2022
Harmful algae that inhabit eutrophic lakes produce cyanotoxic microcystins. Therefore, the relationship between chronic exposure to microcystins via drinking water and organ disorders has been investigated.
Yoshihito Koto, Hideaki Kawahara, Koichi Kurata, Keisuke Yoshikiyo, Ayumi Hashiguchi, Kunihiro Okano, Norio Sugiura, Kazuya Shimizu, Hidehisa Shimizu   +8 more
doaj   +1 more source

Electrochemical aptasensors for ultrasensitive multiplexed detection: Towards a new era of precision diagnostics and environmental monitoring

VIEW, EarlyView.
Electrochemical aptasensors are emerging as powerful platforms for precision diagnostics and environmental monitoring, owing to their high selectivity, programmability and compatibility with miniaturised systems. However, their broader application is constrained by limited signal intensity and challenges in reliable multiplexed detection.
Azadeh Abdi, Ngoan Thi Thao Nguyen, Riccardo Zulli, Jacopo Giaretta, Fariba Dehghani, Syamak Farajikhah   +5 more
wiley   +1 more source

The Effects of Temperature on Microcystin-LR Toxicity to Bosmina Longirostris: Food Web Implications in the Chowan River, North Carolina

, 2023
In the Chowan River, North Carolina, the frequency of Microcystis aeruginosa blooms has increased over recent years with an average 1.9°C rise in June water temperatures since 1975. Zooplankton are an important trophic link for toxins to move up the food
Jupitz, Madison C., NC DOCKS at East Carolina University   +1 more
core  

Effect of Salinity Stress on Gut–Brain–Gonad Axis in the Red‐Eared Slider (Trachemys scripta elegans)

Integrative Zoology, EarlyView.
The increase in salinity leads to changes in the gut microbiota and metabolites of Trachemys scripta elegans, affecting the synthesis and secretion of neurotransmitters or precursors, which can inhibit the secretion of reproductive hormones and affect the self‐renewal and differentiation process of spermatogonial stem cells.
Qiongyu Zhang, Na Li, Xue Tang, Hanru Chen, Meiling Hong, Li Ding   +5 more
wiley   +1 more source

Biodegradation of [D-Leu1] microcystin-LR by a bacterium isolated from sediment of Patos Lagoon estuary, Brazil

Journal of Venomous Animals and Toxins including Tropical Diseases, 2015
Background Toxic cyanobacterial blooms are recurrent in Patos Lagoon, in southern Brazil. Among cyanotoxins, [D-Leu1] microcystin-LR is the predominant variant whose natural cycle involves water and sediment compartments. This study aimed to identify and
Gilmar AF Lemes, Luiza W Kist, Mauricio R Bogo, João S Yunes   +3 more
doaj   +1 more source

The Use of Sodium Hypochlorite at Point-of-Use to Remove Microcystins from Water Containers

Toxins, 2021
Most conventional water treatment plants are not sufficiently equipped to treat both intracellular and extracellular Microcystins in drinking water. However, the effectiveness of sodium hypochlorite in removing Microcystin in containers at the point-of ...
Matodzi Michael Mokoena, Lutendo Sylvia Mudau, Matlou Ingrid Mokgobu, Murembiwa Stanley Mukhola   +3 more
doaj   +1 more source

Nanomaterials' Multigenerational Effects by Single and Joint Exposure in Non‐mammalian Models

Environmental Toxicology, Volume 41, Issue 10, Page 957-974, October 2026.
ABSTRACT Nanotoxicology has mainly focused on single‐generation studies, leaving multigenerational toxicity underexplored. Having animal welfare recently gained importance, we aimed to provide the state‐of‐the‐art of knowledge about multigenerational effects in non‐mammalian models in the case of nanomaterials (NM) single and joint exposure to other ...
Andy Joel Taipe Huisa, Analía Ale, Azael Francisco Silva Neto, Lorena De Mendonça Lucena, Marcelo Estrella Josende, Milena Ferreira de Lima, Rhayanny Kethylly Pereira Santos, Martín Federico Desimone, Priscila Gubert, José María Monserrat   +9 more
wiley   +1 more source

Persistence of Microcystin in Three Agricultural Ponds in Georgia, USA

Toxins
Cyanobacteria and their toxins can have multiple effects on agricultural productivity and water bodies. Cyanotoxins can be transported to nearby crops and fields during irrigation and may pose a risk to animal health through water sources.
Jaclyn E. Smith, James A. Widmer, Jennifer L. Wolny, Laurel L. Dunn, Matthew D. Stocker, Robert L. Hill, Oliva Pisani, Alisa W. Coffin, Yakov Pachepsky   +8 more
doaj   +1 more source