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Gastrointestinal toxicity induced by microcystins
Microcystins (MCs) are produced by certain bloom-forming cyanobacteria that can induce toxicity in various organs, including renal toxicity, reproductive toxicity, cardiotoxicity, and immunosuppressive effects. It has been a significant global environmental issue due to its harm to the aquatic environment and human health.
Wu, Jin-Xia +10 more
openaire +2 more sources
Lake Okeechobee, FL, USA, has been subjected to intensifying cyanobacterial blooms that can spread to the adjacent St. Lucie River and Estuary via natural and anthropogenically-induced flooding events.
Benjamin J Kramer +7 more
doaj +1 more source
"Super-blooms" of cyanobacteria that produce potent and environmentally persistent biotoxins (microcystins) are an emerging global health issue in freshwater habitats.
Melissa A Miller +14 more
doaj +1 more source
An overview of the toxic effect of potential human carcinogen Microcystin-LR on testis
The worldwide occurrence of cyanobacterial blooms due to water eutrophication evokes extreme concerns. These blooms produce cyanotoxins which are hazardous to living organisms.
Yaqoob Lone +2 more
doaj +1 more source
Methods for rapid extraction of microcystin-LR and microcystin-RR
Simple analysis methods using microwave and boiling waterbath to solve the problem for microcystin-LR (MCLR) and microcystin-RR (MCRR) extraction from cyanobacteria cells were studied as a substitute for the traditional solvent extraction methods. Standards were used to confirm the feasibility and efficiency of both methods.
ZHANG Hang-jun +3 more
openaire +1 more source
Microcystins with Modified Adda5-Residues from a Heterologous Microcystin Expression System
Microcystins are hepatotoxic cyclic heptapeptides produced by some cyanobacterial species and usually contain the unusual β-amino acid 3S-amino-9S-methoxy-2S,6,8S-trimethyl-10-phenyl-4E,6E-decadienoic acid (Adda) at position-5. The full microcystin gene cluster from Microcystis aeruginosa PCC 7806 has been expressed in Escherichia coli.
Christopher O. Miles +5 more
openaire +3 more sources
γ-Lindane Increases Microcystin Synthesis in Microcystis aeruginosa PCC7806
HCH factories, and the waste dumpsites associated to its production, have become a global environmental concern, and their runoff could pollute ground and surface waters with high levels of the pollutant.
Laura Ceballos-Laita +5 more
doaj +1 more source
IntroductionMicrocystis aeruginosa (M. aeruginosa), one of the most abundant blue-green algae in aquatic environments, produces microcystin by causing harmful algal blooms (HABs).
Hakyung Lee +9 more
doaj +1 more source
Introduction: Globally, the need for measuring exposure to algal toxins has become urgent due to ever-increasing reports of contamination in sea and freshwater, in shellfish and fish stocks and in aerosols.Methods: To address this issue, we evaluated the
Hui Ma +18 more
doaj +1 more source
Background Cyanobacteria produce a wealth of secondary metabolites, including the group of small cyclic heptapeptide hepatotoxins that constitutes the microcystin family.
Rouhiainen Leo +7 more
doaj +1 more source

