Results 41 to 50 of about 14,066 (175)

Evidence of the cost of the production of microcystins by Microcystis aeruginosa under differing light and nitrate environmental conditions. [PDF]

PLoS ONE, 2012
The cyanobacterium Microcystis aeruginosa is known to proliferate in freshwater ecosystems and to produce microcystins. It is now well established that much of the variability of bloom toxicity is due to differences in the relative proportions of ...
Enora Briand, Myriam Bormans, Catherine Quiblier, Marie-José Salençon, Jean-François Humbert   +4 more
doaj   +1 more source

Strategies for enhancing sensitivity in lateral flow assays

VIEW, EarlyView.
Lateral flow assays (LFAs) are essential for cost‐effective, rapid point‐of‐care diagnostics. However, conventional colourimetric LFAs often lack the sensitivity required for low‐abundance biomarkers. This review evaluates six enhancement strategies: flow modulation, sample preconcentration, advanced reporters, chemical signal amplification, structural
Aylar Eslami Saed, Jacopo Giaretta, Syamak Farajikhah, Fariba Dehghani   +3 more
wiley   +1 more source

Microcystin-LR removal from Microcystis aeruginosa using in natura sugarcane bagasse and activated carbono

, 2016
Microcystin-LR is a type of toxin released by the Microcystis aeruginosa cyanobacteria found in water sources used for human consumption. It can cause illness and even death if not completely removed in conventional water treatment. The retention of this
Thomaz Aurélio Pagioro (4700908), Priscila Tiemi Higuti do Nascimento (6122825), Karina Querne de Carvalho (6098474), Aline Rafaela de Almeida (6122819), Fernando Hermes Passig (6098477)   +4 more
core   +1 more source

Increased Prorenin Expression in the Kidneys May Be Involved in the Abnormal Renal Function Caused by Prolonged Environmental Exposure to Microcystin-LR

Toxics
Toxic algae in eutrophic lakes produce cyanotoxic microcystins. Prior research on the effect of microcystin-LR in the kidney utilized intraperitoneal injections, which did not reflect natural exposure.
Yuuka Hitsuda, Yoshihito Koto, Hideaki Kawahara, Koichi Kurata, Keisuke Yoshikiyo, Kohji Nishimura, Ayumi Hashiguchi, Hideaki Maseda, Kunihiro Okano, Norio Sugiura, Kazuya Shimizu, Hidehisa Shimizu   +11 more
doaj   +1 more source

Effects of Dietary Astaxanthin Supplementation on Energy Budget and Bioaccumulation in Procambarus clarkii (Girard, 1852) Crayfish under Microcystin-LR Stress

Toxins, 2018
This research aimed to study the effects of astaxanthin on energy budget and bioaccumulation of microcystin-leucine-arginine (microcystin-LR) in the crayfish Procambarus clarkii (Girard, 1852).
Zhenhua An, Yingying Zhang, Longshen Sun
doaj   +1 more source

Microcystin-LR incorporated into colonic cells through probenecid-sensitive transporters leads to upregulated MCP-1 expression induced by JNK activation

Toxicology Reports, 2022
Harmful algae that inhabit eutrophic lakes produce cyanotoxic microcystins. Therefore, the relationship between chronic exposure to microcystins via drinking water and organ disorders has been investigated.
Yoshihito Koto, Hideaki Kawahara, Koichi Kurata, Keisuke Yoshikiyo, Ayumi Hashiguchi, Kunihiro Okano, Norio Sugiura, Kazuya Shimizu, Hidehisa Shimizu   +8 more
doaj   +1 more source

Electrochemical aptasensors for ultrasensitive multiplexed detection: Towards a new era of precision diagnostics and environmental monitoring

VIEW, EarlyView.
Electrochemical aptasensors are emerging as powerful platforms for precision diagnostics and environmental monitoring, owing to their high selectivity, programmability and compatibility with miniaturised systems. However, their broader application is constrained by limited signal intensity and challenges in reliable multiplexed detection.
Azadeh Abdi, Ngoan Thi Thao Nguyen, Riccardo Zulli, Jacopo Giaretta, Fariba Dehghani, Syamak Farajikhah   +5 more
wiley   +1 more source

Synthesis and use of the protein phosphatase affinity matrices microcystin-sepharose and microcystin-biotin-sepharose

, 2007
Microcystin-based affinity matrices have been utilized to demonstrate the association of signaling proteins with protein phosphatases and for the purification of low-abundance microcystin-sensitive protein phosphatases.
Haystead, Timothy A.J., MacKintosh, Carol; id_orcid, Moorhead, Greg B.G., Timothy A. J. Haystead, Greg B. G. Moorhead, Carol MacKintosh   +5 more
core   +1 more source

Effects of different doses of microcystin-LR exposure on gut development and the microbiota of Xenopus laevis tadpoles

BMC Microbiology
Background Although the acute toxicity of microcystin-LR has been widely confirmed, its effects on aquatic organisms at environmental concentrations have not been systematically studied.
Jinjin Li, Yuanyuan Zhang, Jiajia Ni, Wenxuan Hou, Lei Huang, Hanping Pan, Chenxu Wang, Kaixin Wang, Shaoyuan Zuo, Jiahao Dong, Mingyu Zhang   +10 more
doaj   +1 more source

Selectivity and potency of microcystin congeners against OATP1B1 and OATP1B3 expressing cancer cells. [PDF]

PLoS ONE, 2014
Microcystins are potent phosphatase inhibitors and cellular toxins. They require active transport by OATP1B1 and OATP1B3 transporters for uptake into human cells, and the high expression of these transporters in the liver accounts for their selective ...
Timo H J Niedermeyer, Abigail Daily, Monika Swiatecka-Hagenbruch, Jeffrey A Moscow   +3 more
doaj   +1 more source