Results 101 to 110 of about 10,733 (203)

Machine Learning‐Based Prediction of Sperm Retrieval Outcomes in Patients With Klinefelter Syndrome: A Multicenter Study With External Validation

Andrology, EarlyView.
ABSTRACT Background The Klinefelter syndrome is a common genetic cause of male infertility, and testicular sperm extraction (TESE) enables sperm retrieval in a subset of affected patients. However, predicting TESE success remains challenging due to the heterogeneous clinical and endocrinological presentation of the Klinefelter syndrome.
Murat Gül, Ali Şahin, Cevahir Özer, Mesut Altan, Tansu Güdelci, Kadir Can Sahin, Mehmet Hamza Gültekin, Muhammed Arif İbis, Mesut Berkan Duran, Burak Sivaslıoğlu, Eray Hasırcı, Mert Kılıç, Ali Can Albaz, Gökhan Çeker, Gianmaria Salvio   +14 more
wiley   +1 more source

Laser capture microdissection for forensic DNA analysis

, 2011
Laser capture microdissection (LCM) is a unique tool for precise separation of target cells from forensic mixtures. Cells isolated by LCM can subsequently be used for the generation of pure DNA profiles.
Deforce, Dieter, Dieter Deforce, Vandewoestyne, Mado, Mado Vandewoestyne   +3 more
core   +1 more source

Multidimensional Determinants of Quality of Life in Men With Klinefelter Syndrome: A Narrative Review of Workshop Evidence

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome (KS), typically characterized by a 47, XXY karyotype, is the most common sex chromosomal aneuploidy in males, with a prevalence of approximately one in 600–660 individuals. Despite its frequency, the syndrome remains significantly underdiagnosed, with 50%–75% of affected individuals never receiving a clinical ...
Francesca Allosso, Lucia Digitale Selvaggio, Daniela Pasquali   +2 more
wiley   +1 more source

Advances in isolation and characterization of homogeneous cell populations using laser microdissection [PDF]

, 2005
The isolation and characterization of homogeneous cell populations are of great importance for the analysis of gene expression, because normal tissues contain various types of cells, and the differences in the populations of isolated cells exert ...
Kotani, H., Kobayashi, T., Mizuaral, S., Takahashi, K.   +3 more
core  

Supplementary Tables 1-4 from Global Gene Expression Profile of Nasopharyngeal Carcinoma by Laser Capture Microdissection and Complementary DNA Microarrays

, 2004
Supplementary Tables 1-4 from Global Gene Expression Profile of Nasopharyngeal Carcinoma by Laser Capture Microdissection and Complementary DNA ...
John W. Gillespie (11261129), Vyomesh Patel (29261), Virote Sriuranpong (8118407), Alfredo A. Molinolo (8878619), Apiwat Mutirangura (16235), Siripornchai Supanakorn (14978257), Veerachai Kerekhanjanarong (14978254), Pakpoom Supiyaphun (14978260), J. Silvio Gutkind (90145), Narin Voravud (14978266), Samreung Rangdaeng (14978263), Panomwat Amornphimoltham (14889146)   +11 more
core   +1 more source

Sox9 and Vasa Gene Expression During Gonadal Differentiation in Larvae of the Urodele Amphibian Ambystoma mexicanum

Acta Zoologica, EarlyView.
ABSTRACT The study of genes involved in sexual differentiation, as Vasa and Sox9, is of great importance, as they serve as specific markers for the germline and the male differentiation pathway, respectively. This study characterized using immunofluorescence the expression of the Vasa and Sox9 genes and laminin during gonadal differentiation in larvae ...
Eva Mendoza‐Cruz, Maricela Villagrán‐SantaCruz   +1 more
wiley   +1 more source

The dual incretin agonist tirzepatide blunts nicotine‐induced behaviours and neurochemistry in male mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Nicotine dependence remains one of the leading causes of morbidity and mortality worldwide, with high relapse rates and post‐cessation weight gain representing persistent barriers to sustained abstinence. The incretin hormones glucose‐dependent insulinotropic polypeptide (GIP) and glucagon‐like peptide‐1 (GLP‐1) have ...
Christian E. Edvardsson, Thaynnam A. Emous, Sarah Witley, Mia Ericson, Louise Adermark, Elisabet Jerlhag   +5 more
wiley   +1 more source

Shared Origin of Y and Z Chromosomes in the Turnover of XY and ZW Systems in the Frog Glandirana rugosa

Biomolecules
The Japanese frog Glandirana rugosa, endemic to Japan, exhibits both XY and ZW sex determination systems in different populations, representing a rare example of sex chromosome turnover within a single species.
Yukako Katsura, Divya Shaji, Kazumi Matsubara, Rei Kajitani, Tariq Ezaz, Ikuo Miura   +5 more
doaj   +1 more source

Structural and functional changes to the testis after conventional versus microdissection testicular sperm extraction

, 2005
To compare, in a retrospective study, the ultrasound findings and hormonal changes after testicular sperm extraction (TESE) using the conventional multiple biopsy approach and the more recent microdissection technique.
Yagan, Neda, Schlegel, Peter N, Ramasamy, Ranjith   +2 more
core   +1 more source

Mechanisms underpinning the progression of nondysplastic Barrett's oesophagus to cancer

The FEBS Journal, EarlyView.
Barrett's oesophagus confers a low but significant cancer risk. The condition is common but we do not have effective biomarkers to identify susceptible patients. We believe that there is no single factor that determines cancer risk and an understanding of the combinations of interactions (via gene expression and natural selection) between the Barrett's
Yannick H. Derwa, Meng‐Lay Lin, Stuart A. C. McDonald   +2 more
wiley   +1 more source