Results 101 to 110 of about 47,561 (246)

Genetic analysis of primary lung interdigitating dendritic cell sarcomas

The Journal of Pathology, Volume 269, Issue 4-5, Page 387-398, August 2026.
Abstract Interdigitating dendritic cell sarcomas (IDCSs) are rare tumors that commonly arise in the hematopoietic system and rarely outside. The genetic drivers of IDCS carcinogenesis are unknown; therefore, therapeutic options are limited. We investigated somatic gene mutations and copy‐number alterations (CNAs) in nine IDCSs arising in the lung by ...
Mikhail S Ermakov, Juliana Faria Filipe, Sylvia Eidenhammer, German Ott, Iris Halbwedl, Karl Kashofer, Helmut Popper   +6 more
wiley   +1 more source

An elastic segment of the whisker shaft enables coding of the whisking phase via whisker torsion in rats and mice

The Anatomical Record, Volume 309, Issue 7, Page 1910-1924, July 2026.
An elastic segment was found in the basal part of the whisker shaft in rats and mice. Application of force to the whisker bulb of isolated follicles caused bending and twisting of this segment. Active whisker movements deform this segment, causing whisker shaft deflection and selective activation of mechanoreceptors at different phases of whisking ...
Sebastian Haidarliu, Guy Nelinger, Luka Gantar, Ehud Ahissar, Inbar Saraf‐Sinik   +4 more
wiley   +1 more source

Semen Quality and DNA Fragmentation After Limited Testicular Sperm Extraction in Non‐Azoospermic Men With ART Failure: A Retrospective Matched Cohort Study

Health Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background and Aims Testicular sperm extraction (TESE) is sometimes used in non‐azoospermic men with persistent infertility, particularly in cases of high sperm DNA fragmentation index (DFI) or repeated intracytoplasmic sperm injection (ICSI) failure.
Naser Amirjannati, Hamed Akhavizadegan, Arash Mohazzab, Negin Amirjannati, Manizheh Fathalian, Ghazaleh Eslamian   +5 more
wiley   +1 more source

Second chance in fertility: a comprehensive narrative review of redo micro-TESE outcomes after initial failure

Asian Journal of Andrology
When microdissection testicular sperm extraction (micro-TESE) fails, a redo procedure may be the only option for patients who want a biological child. However, there are many gaps of knowledge surrounding the procedure, which need to be addressed to help
Haitham Elbardisi, Emre Bakircioglu, Wen Liu, Darren Katz   +3 more
doaj   +1 more source

Cancer Heterogeneity and Cancer Cell Plasticity: Molecular Mechanisms and Precision Therapy

MedComm, Volume 7, Issue 7, July 2026.
Tumor progression is driven by heterogeneity occurring across multiple biological scales. At the molecular level, tumor cells exhibit alterations across distinct omics layers, including genomic mutations, epigenomic reprogramming, transcriptional changes, and proteomic remodeling, collectively shaping tumor cell phenotypes and functional states.
Hanwen Hu, Zhixing Hao, Lili Li, Huiying Liu, Chenghui Yang, Zhen Wang   +5 more
wiley   +1 more source

Incidental seminoma in nonobstructive azoospermia: a case report

F&S Reports
Objective: To report on the incidental finding of invasive seminoma in a patient with nonobstructive azoospermia during microdissection testicular sperm extraction. Design: Case report.
Jonathan Gal, MD, Juan Miguel Mosquera, MD, MSc, Brian D. Robinson, MD, Peter N. Schlegel, MD   +3 more
doaj   +1 more source

Development of a nomogram for sperm retrieval at microTESE for idiopathic non‐obstructive azoospermia in a multi‐center cohort study

Andrology, Volume 14, Issue 5, Page 1202-1208, July 2026.
Abstract Background Non‐obstructive azoospermia (NOA) affects approximately 10% of infertile men and represents a major challenge in assisted reproductive technology (ART). A model that includes histological variants could be helpful in predicting sperm retrieval rate (SRR) after microdissection testicular sperm extraction (mTESE) in patients affected ...
Giorgio Ivan Russo, Edoardo Pozzi, Fausto Negri, Marco Falcone, Emanuele Zupo, Mirko Preto, Maria Giovanna Asmundo, Sandrine Chamayou, Murat Dursun, Ateş Kadıoğlu, Andrea Salonia   +10 more
wiley   +1 more source

The Molecular Diagnosis of Myopathies: Integrating Genomic, Proteomic, and Pathological Insights Toward Precision Medicine

Clinical Genetics, Volume 110, Issue 1, Page 15-28, July 2026.
Advances in genomic, proteomic, and transcriptomic technologies are transforming the diagnosis of genetic myopathies. When integrated with traditional muscle pathology, multi‐omics approaches improve diagnostic yield, clarify disease mechanisms, and support more precise, mechanism‐based therapeutic strategies for patients with neuromuscular disorders ...
Ludmila Alem, Denise de Abreu Pereira, Katia Carneiro   +2 more
wiley   +1 more source

Revisiting non‐obstructive azoospermia: Is there a best way to retrieve testicular sperm?

Reproductive Medicine and Biology
Background Microdissection TESE has been considered the “gold standard” for retrieving testicular sperm in cases of non‐obstructive azoospermia (NOA) despite limited scientific support. Here we compare all aspects of microdissection TESE with testis fine
Satoru Kanto, Kentaro Ichioka, Yuri Sato, Yoshihiko Uchino, Takayuki Tanaka, Mareyuki Endo   +5 more
doaj   +1 more source

GLP‐1 Receptors Are Enriched in the Lymphatic Endothelium and Their Pharmacological Activation With Semaglutide Improves the Pumping Capacity of Lymphatic Vessels

Microcirculation, Volume 33, Issue 5, July 2026.
ABSTRACT Objectives Recent clinical studies have suggested that glucagon‐like peptide‐1 receptor (GLP‐1R) agonists may be effective therapies to treat or reduce the risk of developing secondary lymphedema. In this study, we aimed to (1) determine if GLP‐1Rs are present in the lymphatic vasculature and characterize their expression, and (2) assess the ...
Mary E. Schulz, Victoria L. Akerstrom, Joseph H. Dayan, Jorge A. Castorena‐Gonzalez   +3 more
wiley   +1 more source