Results 81 to 90 of about 10,733 (203)

The Hidden Architecture of Pancreatic Ducts: 3D Anatomical Reconstruction and Its Implication on Pancreatic Resection

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background/Purpose Postoperative pancreatic fistula (POPF) is a common complication after pancreatic surgery and its mechanisms remain incompletely understood. While the diameter of the main pancreatic duct is well‐known to be a risk factor of POPF, the impact of branch duct's (BD) anatomy is not known.
Sébastien Frey   +9 more
wiley   +1 more source

Using the Parafilm-assisted Microdissection (PAM) Method to Sample Rodent Nucleus Accumbens

open access: yesBio-Protocol, 2020
Microdissection techniques are very important for anatomical and functional studies focused on neuroscience, where it is often necessary microdissect specific brain areas to perform molecular or anatomical analyses. The parafilm®-assisted microdissection
Marco Pagliusi Jr.   +5 more
doaj   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik   +3 more
wiley   +1 more source

Microdissection of the An. atroparvus polytene X chromosome.

open access: yes, 2017
Chromosome preparation from ovarian nurse cells before (a) and after (b) microdissection of the X chromosome.
Igor V. Sharakhov (130527)   +3 more
core   +1 more source

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu   +5 more
wiley   +1 more source

Work flow of laser microdissection of rapeseed.

open access: yes, 2012
(A) Progress of laser microdissection workflow applied to rapeseed. Hypocotyl and radicle (HR), inner cotyledon (IC), outer cotyledon (OC), seed coat and endosperm (SE) were successively dissected from rapeseed. (B) Micrographs of dissected tissues.
Sara Agnolet (124947)   +4 more
core   +1 more source

Mass Spectrometry Imaging–Guided Proteomics, an Emerging Frontier in Spatial Biology

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Spatial heterogeneity is a defining feature of tissue organization, yet conventional proteomic analysis provides limited information about the spatial origins of identified proteins. Spatially guided proteomics addresses this limitation by using tissue imaging techniques to select regions of interest (ROIs) for localized analysis by liquid ...
Kenneth Weke   +4 more
wiley   +1 more source

Brain Microdissection in Mouse Models v2

open access: yes
This protocol describes a method for the microdissection of a mouse brain hemisphere that allows for subsequent analysis of specific brain regions.
Serena McElroy   +3 more
core   +1 more source

Molecular Characterization of Testicular Germ Cell Tumors Using Tissue Microdissection

open access: yes, 2020
Testicular germ cell tumors are among the most common malignancies seen in children and young adults. Genomic studies have identified characteristic molecular profiles in testicular cancer, which are associated with histologic subtypes and may predict ...
Montironi R.   +24 more
core   +1 more source

TP53 mutations orchestrate partial EMT states in oral squamous cell carcinoma: spatially resolved and in vitro preliminary insights into tumour plasticity

open access: yesThe Journal of Pathology, EarlyView.
Abstract TP53 is the most frequently mutated gene in oral squamous cell carcinoma (OSCC); however, its role in promoting epithelial–mesenchymal transition (EMT) and tumour progression remains unclear, particularly within the context of intra‐tumour heterogeneity.
Rana Alaaeldin Ibrahim   +9 more
wiley   +1 more source

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