Results 81 to 90 of about 10,733 (203)
ABSTRACT Background/Purpose Postoperative pancreatic fistula (POPF) is a common complication after pancreatic surgery and its mechanisms remain incompletely understood. While the diameter of the main pancreatic duct is well‐known to be a risk factor of POPF, the impact of branch duct's (BD) anatomy is not known.
Sébastien Frey +9 more
wiley +1 more source
Using the Parafilm-assisted Microdissection (PAM) Method to Sample Rodent Nucleus Accumbens
Microdissection techniques are very important for anatomical and functional studies focused on neuroscience, where it is often necessary microdissect specific brain areas to perform molecular or anatomical analyses. The parafilm®-assisted microdissection
Marco Pagliusi Jr. +5 more
doaj +1 more source
Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik +3 more
wiley +1 more source
Microdissection of the An. atroparvus polytene X chromosome.
Chromosome preparation from ovarian nurse cells before (a) and after (b) microdissection of the X chromosome.
Igor V. Sharakhov (130527) +3 more
core +1 more source
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu +5 more
wiley +1 more source
Work flow of laser microdissection of rapeseed.
(A) Progress of laser microdissection workflow applied to rapeseed. Hypocotyl and radicle (HR), inner cotyledon (IC), outer cotyledon (OC), seed coat and endosperm (SE) were successively dissected from rapeseed. (B) Micrographs of dissected tissues.
Sara Agnolet (124947) +4 more
core +1 more source
Mass Spectrometry Imaging–Guided Proteomics, an Emerging Frontier in Spatial Biology
ABSTRACT Spatial heterogeneity is a defining feature of tissue organization, yet conventional proteomic analysis provides limited information about the spatial origins of identified proteins. Spatially guided proteomics addresses this limitation by using tissue imaging techniques to select regions of interest (ROIs) for localized analysis by liquid ...
Kenneth Weke +4 more
wiley +1 more source
Brain Microdissection in Mouse Models v2
This protocol describes a method for the microdissection of a mouse brain hemisphere that allows for subsequent analysis of specific brain regions.
Serena McElroy +3 more
core +1 more source
Molecular Characterization of Testicular Germ Cell Tumors Using Tissue Microdissection
Testicular germ cell tumors are among the most common malignancies seen in children and young adults. Genomic studies have identified characteristic molecular profiles in testicular cancer, which are associated with histologic subtypes and may predict ...
Montironi R. +24 more
core +1 more source
Abstract TP53 is the most frequently mutated gene in oral squamous cell carcinoma (OSCC); however, its role in promoting epithelial–mesenchymal transition (EMT) and tumour progression remains unclear, particularly within the context of intra‐tumour heterogeneity.
Rana Alaaeldin Ibrahim +9 more
wiley +1 more source

