Results 61 to 70 of about 47,561 (246)

Molecular approach of the fragile chromosomal region Xq31-34 in cattle (Bos taurus) by microdissection and DOP-PCR Aproximação molecular da região cromossômica frágil Xq31-34 em bovinos (Bos taurus) utilizando microdissecação cromossômica e DOP-PCR

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2008
Fragile sites (FS) are chromosomal regions where the normal compactation of chromatine is not observed. FRAXA (Fra Xq27.3, X sexual chromosome) is one of the most studied FS in humans.
S. Llambí, M.V. Arruga
doaj   +1 more source

Innervation of the tubarial glands: A hypothesis‐driven anatomical review

The Anatomical Record, EarlyView.
Abstract The tubarial glands have been described as a macroscopic bilateral glandular complex in the posterolateral nasopharynx near the torus tubarius and the pharyngeal opening of the Eustachian tube. Since their recognition on prostate‐specific membrane antigen‐based imaging, their anatomical classification has remained debated, with converging ...
Mugurel Constantin Rusu, Ivan Varga, Răzvan Costin Tudose   +2 more
wiley   +1 more source

The Potential Role of Synovial T Cell Infiltration Following Knee Joint Injury in Symptoms and Progression to Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective Identification of osteoarthritis (OA)–specific synovial inflammatory pathways and their temporal relevance is critical for therapeutic targeting. We compared mononuclear inflammatory/immune cell responses following joint injury that does or does not lead to OA to define bona fide OA‐associated cellular events.
Babak Moradi, Miriam T. Jackson, Cindy C. Shu, Susan M. Smith, Margaret M. Smith, Sanaa Zaki, Hadrian Platzer, Nils Rosshirt, David Giangreco, Carla R. Scanzello, Christopher B. Little   +10 more
wiley   +1 more source

Identification of Genomic Loci Responsible for the Formation of Nuclear Domains Using Lampbrush Chromosomes

Non-Coding RNA, 2019
In the cell nuclei, various types of nuclear domains assemble as a result of transcriptional activity at specific chromosomal loci. Giant transcriptionally active lampbrush chromosomes, which form in oocyte nuclei of amphibians and birds enable the ...
Alla Krasikova, Tatiana Kulikova
doaj   +1 more source

Positional Relationship Between the Orbicularis Oculi and Zygomaticus Complex Muscles by Ultrasonography: New Anatomical Insights for Crow's Feet Injection

Clinical Anatomy, EarlyView.
ABSTRACT The orbicularis oculi muscle (OOc) is strongly associated with facial aging as its contraction causes the formation of crow's feet. Botulinum neurotoxin (BoNT) injection is a representative treatment targeting muscle. The aim of this study was to demonstrate the anatomical relationship between the OOc and the zygomaticus complex muscles, and ...
Jiong‐Zhen Piao, Ji‐Hyun Lee, Kyung‐Seok Hu, Hee‐Jin Kim   +3 more
wiley   +1 more source

High incidence of Y‐chromosome mosaicism in male and female individuals with mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy

Epilepsia, EarlyView.
Abstract Objective Mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE) is an underrecognized pediatric cortical lesion associated with somatic X‐linked SLC35A2 variants in approximately 50% of individuals. The genetic etiology in individuals without detectable SLC35A2 mutations remains undefined, which limits
Erica Cecchini, Till Hartlieb, Ahmed Gaballa, Katja Kobow, Mitali Katoch, Paraskevi Chasani, Georgia Vasileiou, Wiebke Hofer, Lea M. Reisch, Manfred Kudernatsch, Christian G. Bien, Roland Coras, Ingmar Blümcke, Lucas Hoffmann   +13 more
wiley   +1 more source

Engineering a 3D-Bioprinted Model of Human Heart Valve Disease Using Nanoindentation-Based Biomechanics

Nanomaterials, 2018
In calcific aortic valve disease (CAVD), microcalcifications originating from nanoscale calcifying vesicles disrupt the aortic valve (AV) leaflets, which consist of three (biomechanically) distinct layers: the fibrosa, spongiosa, and ventricularis.
Dewy C. van der Valk, Casper F. T. van der Ven, Mark C. Blaser, Joshua M. Grolman, Pin-Jou Wu, Owen S. Fenton, Lang H. Lee, Mark W. Tibbitt, Jason L. Andresen, Jennifer R. Wen, Anna H. Ha, Fabrizio Buffolo, Alain van Mil, Carlijn V. C. Bouten, Simon C. Body, David J. Mooney, Joost P. G. Sluijter, Masanori Aikawa, Jesper Hjortnaes, Robert Langer, Elena Aikawa   +20 more
doaj   +1 more source

Site-specific gene expression profiling as a novel strategy for unravelling keloid disease pathobiology. [PDF]

PLoS ONE, 2017
Keloid disease (KD) is a fibroproliferative cutaneous tumour characterised by heterogeneity, excess collagen deposition and aggressive local invasion.
N Jumper, T Hodgkinson, R Paus, A Bayat
doaj   +1 more source

Spatial omics in the AI era: Technologies, algorithmic ecosystems, biological applications, and large model perspectives

iMeta, EarlyView.
This review focuses on spatial omics, covering the introduction and comparison of technology platforms, explanation and recommendation of algorithm ecology, demonstration of biological applications, and prospect of large models. It aims to help researchers in the interdisciplinary field of spatial omics quickly understand the current situation and ...
Haoxiu Wang, Xinwang Yang, Siheng Wang, Zhe Yang, Xiuhui Yang, Yutong Yang, Zirong Li, Yuqi Ren, Qianqian Zhang, Bowen Zhao, Jingming Xiao, Yidong Wang, Junhao Dong, Zhenhao Kou, Jie Li, Liqun Yang, Erhu Zhao, Gregory Fonseca, Ruibang Luo, Mingyu Yang, Hongjuan Cui, Gengjie Jia, Dan Wang, Haoyang Li, Jun Ding, Zhiyuan Yuan, Haojing Shao   +26 more
wiley   +1 more source

TP53 Abnormalities are frequent and early events in the sequential pathogenesis of gallbladder carcinoma§

Annals of Hepatology, 2005
Background: Gallbladder carcinoma (GBC) is a frequent neoplasm in Hispanic and native American populations. GBC is preceded by gallstones, chronic cholecystitis and dysplastic changes of the gallbladder epithelium.
Mauricio Moreno, Fernando Pimentel, Adi F. Gazdar, Ignacio I. Wistuba, Juan F. Miquel   +4 more
doaj   +1 more source