Results 131 to 140 of about 778,156 (254)

Induced Core‐Shell Transformation in Agarose‐Chitosan Nanoreactor Beads Enable Single Channel Coding for dPCR Multiplexing

open access: yesSmall, EarlyView.
Hybrid agarose–chitosan beads undergo a pH‐dependent reorganization into stable core–shell structures upon heating. The resulting tunable optical shell/core contrasts enable bead‐based coding for multiplex PCR. This approach allows sample multiplexing with simple detection systems and functionally exploits a previously unrecognized structure‐forming ...
Katharina Heise   +12 more
wiley   +1 more source

Organic Electrochemical Transistor Arrays With Integrated Lipid‐Sealed Femtolitre Chambers For Simultaneous Electrical and Optical Detection of Membrane Protein Activity

open access: yesSmall, EarlyView.
A scalable array of 52 ion‐sensitive organic electrochemical transistors featuring integrated independent lipid‐bilayer‐sealed microwells for simultaneous electrical and fluorescence detection of membrane proteins. α‐hemolysin pore formation produces correlated changes in transistor conductance and fluorescence, demonstrating localized ion transport ...
S. Kojima   +6 more
wiley   +1 more source

Microfluidic Molecular Diagnostic Chips: Functional Modules, Integration Strategies, and Emerging Applications

open access: yesSmall Methods, EarlyView.
This comprehensive review delivers an engineering‐centric analysis of microfluidic molecular diagnostic chips, breaking them down into foundational modules from fluid manipulation to bio‐sensing. Beyond chip design, it evaluates sample‐to‐answer integration strategies and commercial readiness levels.
Donghoon Koo   +7 more
wiley   +1 more source

Electrochemical aptasensors for ultrasensitive multiplexed detection: Towards a new era of precision diagnostics and environmental monitoring

open access: yesVIEW, EarlyView.
Electrochemical aptasensors are emerging as powerful platforms for precision diagnostics and environmental monitoring, owing to their high selectivity, programmability and compatibility with miniaturised systems. However, their broader application is constrained by limited signal intensity and challenges in reliable multiplexed detection.
Azadeh Abdi   +5 more
wiley   +1 more source

Efficacy and reliability of long-term implantation of multi-channel microelectrode arrays in the optical nerve sheath of rabbit eyes

open access: yes, 2011
In addition to epiretinal and subretinal areas, the optic nerve (ON) is also a candidate location for implanting visual prosthesis to restore vision of patients with retinitis pigmentosa (RP).
Li XQ   +6 more
core  

Investigation of the mechanisms and modulation of irinotecan‐induced emesis in Suncus murinus

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Irinotecan is a widely used chemotherapeutic agent that frequently causes nausea and emesis. Its emetic mechanism of action is poorly understood and the choice of drugs to reduce nausea and emesis is largely empirical. Experimental Approach Using Suncus murinus, we examined (i) the dose–response and temporal profile of ...
Zengbing Lu   +7 more
wiley   +1 more source

Measuring Cell Impedance by Microelectrode Array

open access: yes, 2013
Microelectrode array (MEA) has been used in cell physiology for many years. It features the non-invasive, long-term, and space resolution method to record cell signals.
Chen, Yu-Chung, 陳昱中
core  

Preliminary study of thermal impact of a microelectrode array implanted in the brain [PDF]

open access: yes, 2006
journal articleOne requirement of a chronically implantable, wireless neural interface device is the integration of electronic circuitry with the microelectrode array.
Harrison, Reid R.;Normann, Richard A.   +1 more
core  

Neural signal transmission measurements with a conductive polymer microelectrode array

open access: yes, 2011
The neural activity of dissociated cultures of mouse cortical neurons was measured with a conductive polymer microelectrode array. Each electrode was electrochemically polymerized from (3,4-ethylenedioxythiophene)-poly(styrenesulfonate) and ...
Tobias Nyberg   +9 more
core   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad   +6 more
wiley   +1 more source

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