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Endometrial Tumour Microenvironment
2020Endometrial cancer (EC) is the most common gynaecological tumour in developed countries, and its incidence is increasing in part due to the prevalence of obesity and its related hormone dysregulation. As described in this chapter, the tumour microenvironment plays a principal role in unopposed oestrogen stimulation promoting tumour cell proliferation ...
Carlos, Casas-Arozamena, Miguel, Abal
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Decorin in the Tumor Microenvironment
2020The tumor microenvironment plays a determining role in cancer development through a plethora of interactions between the extracellular matrix and tumor cells. Decorin is a prototype member of the SLRP family found in a variety of tissues and is expressed in the stroma of various forms of cancer. Decorin has gained recognition for its essential roles in
Kornélia, Baghy +3 more
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Microenvironment: Neighbourhood watch
Nature, 2011In the fight against myeloma, researchers are investigating its interactions with molecular neighbours in the bone marrow.
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The tumour microenvironment in pancreatic cancer — clinical challenges and opportunities
Nature Reviews Clinical Oncology, 2020Won Jin Ho +2 more
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The updated landscape of tumor microenvironment and drug repurposing
Signal Transduction and Targeted Therapy, 2020Wei-Lin Jin +2 more
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Hypoxic microenvironment in cancer: molecular mechanisms and therapeutic interventions
Signal Transduction and Targeted Therapy, 2023Zhou Wence, Fangfang Han
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