Results 81 to 90 of about 56,675 (350)

Integrated movable micromechanical structures for sensors and actuators [PDF]

open access: yes, 1988
Movable pin-joints, gears, springs, cranks, and slider structures with dimensions measured in micrometers have been fabricated using silicon microfabrication technology.
Fan, Long-Sheng   +2 more
core   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

open access: yesAdvanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong   +4 more
wiley   +1 more source

Microscale adhesion patterns for the precise localization of amoeba [PDF]

open access: yes, 2008
In order to get a better understanding of amoeba-substrate interactions in the processes of cellular adhesion and directional movement, we engineered glass surfaces with defined local adhesion characteristics at a micrometric scale. Amoeba (Dictyostelium
Chang   +16 more
core   +4 more sources

A Superhydrophobic 3D Cell Culture System Reveals the Mechanobiological Role of Cancer‐Associated Fibroblasts in Prostate Cancer Metastasis

open access: yesAdvanced Healthcare Materials, EarlyView.
A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter   +5 more
wiley   +1 more source

Microfabrication of Nonplanar Polymeric Microfluidics

open access: yesMicromachines, 2018
For four decades, microfluidics technology has been used in exciting, state-of-the-art applications. This paper reports on a novel fabrication approach in which micromachining is used to create nonplanar, three-dimensional microfluidic chips for ...
Pin-Chuan Chen   +2 more
doaj   +1 more source

Micro-evaporators for kinetic exploration of phase diagrams

open access: yes, 2006
We use pervaporation-based microfluidic devices to concentrate species in aqueous solutions with spatial and temporal control of the process.
A. Myerson   +7 more
core   +1 more source

A Physiological Microfluidic Blood–Brain‐Barrier Model for In Vitro Study of Nanoparticle Trafficking and Accumulation

open access: yesAdvanced Healthcare Materials, EarlyView.
A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.
Bryan B. Nguyen   +9 more
wiley   +1 more source

Carbon Nanotube-Based Chemiresistive Sensors

open access: yesSensors, 2017
The development of simple and low-cost chemical sensors is critically important for improving human life. Many types of chemical sensors have been developed.
Ruixian Tang   +3 more
doaj   +1 more source

3D Neuro-electronic interface devices for neuromuscular control: Design studies and realisation steps [PDF]

open access: yes, 1995
In order to design the shape and dimensions of new 3D multi-microelectrode information transducers properly, i. e. adapted to the scale of information delivery to and from peripheral nerve fibres, a number of studies were, and still are, being performed ...
Frieswijk, Theo A.   +4 more
core   +2 more sources

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

open access: yesAdvanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su   +8 more
wiley   +1 more source

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