Results 11 to 20 of about 30,332 (287)

MICROFILAMENTS AND CELL LOCOMOTION [PDF]

The Journal of Cell Biology, 1971
The role of microfilaments in generating cell locomotion has been investigated in glial cells migrating in vitro. Such cells are found to contain two types of microfilament systems: First, a sheath of 50–70-A in diameter filaments is present in the ...
Spooner, Brian S., Wessells, Norman K., Yamada, Kenneth M.   +2 more
core   +8 more sources

Contraction of cross-linked actomyosin bundles [PDF]

, 2012
Cross-linked actomyosin bundles retract when severed in vivo by laser ablation, or when isolated from the cell and micromanipulated in vitro in the presence of ATP. We identify the time scale for contraction as a viscoelastic time tau, where the viscosity is due to (internal) protein friction.
Bonnet I, Callan-Jones A C, Cavey M, Colombelli J, Deguchi S, Günther S, Howard J, Joanny J F, Katoh K, Natsuhiko Yoshinaga, Philippe Marcq, Pollard T D, Rodriguez-Diaz A   +12 more
arxiv   +3 more sources

Trapping and Wiggling: Elastohydrodynamics of Driven Microfilaments [PDF]

Biophysical Journal, 1997
We present a general theoretical analysis of semiflexible filaments subject to viscous drag or point forcing. These are the relevant forces in dynamic experiments designed to measure biopolymer bending moduli. By analogy with the ``Stokes problems" in hydrodynamics (fluid motion induced by that of a wall bounding a viscous fluid), we consider the ...
Wiggins, Chris H., Riveline, D., Ott, A., Goldstein, Raymond E.   +3 more
arxiv   +8 more sources

On the dynamics of the microfilament system in HeLa cells [PDF]

The Journal of Cell Biology, 1982
We measured the pools of unpolymerized and filamentous actin in homogenates of HeLa cells made in several different lysis buffers, as well as after treatment of cells with a variety of chemicals or trypsin, and after adenovirus (type 2) infection.
Blikstad, Ingrid, Carlsson, Lars
core   +8 more sources

Instability-driven Oscillations of Elastic Microfilaments [PDF]

arXiv, 2018
Cilia and flagella are highly conserved slender organelles that exhibit a variety of rhythmic beating patterns from non-planar cone-like motions to planar wave-like deformations. Although their internal structure, composed of a microtubule-based axoneme driven by dynein motors, is known, the mechanism responsible for these beating patterns remains ...
Feng Ling, Hanliang Guo, Eva Kanso
arxiv   +6 more sources

Regulation of the integrin αVβ3- actin filaments axis in early osteogenic differentiation of human mesenchymal stem cells under cyclic tensile stress [PDF]

Cell Communication and Signaling, 2023
Background Integrins are closely related to mechanical conduction and play a crucial role in the osteogenesis of human mesenchymal stem cells. Here we wondered whether tensile stress could influence cell differentiation through integrin αVβ3.
Yan Peng, Rongmei Qu, Yuchao Yang, Tingyu Fan, Bing Sun, Asmat Ullah Khan, Shutong Wu, Wenqing Liu, Jinhui Zhu, Junxin Chen, Xiaoqing Li, Jingxing Dai, Jun Ouyang   +12 more
doaj   +2 more sources

Genome-wide characterization and expression analysis of the ADF gene family in response to salt and drought stress in alfalfa (Medicago sativa) [PDF]

Frontiers in Plant Science
The microfilament cytoskeleton, formed by the process of actin polymerization, serves not only to support the morphology of the cell, but also to regulate a number of cellular activities.
Mengmeng Shi, Yike Wang, Peng Lv, Yujie Gong, Qi Sha, Xinyan Zhao, Wen Zhou, Lingtao Meng, Zegang Han, Lingxiao Zhang, Lingxiao Zhang, Yongwang Sun, Yongwang Sun   +12 more
doaj   +2 more sources

Mechanical Sensing Element PDLIM5 Promotes Osteogenesis of Human Fibroblasts by Affecting the Activity of Microfilaments

Biomolecules, 2021
Human skin fibroblasts (HSFs) approximate the multidirectional differentiation potential of mesenchymal stem cells, so they are often used in differentiation, cell cultures, and injury repair. They are an important seed source in the field of bone tissue
Xiaolan Huang, Rongmei Qu, Yan Peng, Yuchao Yang, Tingyu Fan, Bing Sun, Asmat Ullah Khan, Shutong Wu, Kuanhai Wei, Chujiang Xu, Jingxing Dai, Jun Ouyang, Shizhen Zhong   +12 more
doaj   +1 more source

Novel MYO1D Missense Variant Identified Through Whole Exome Sequencing and Computational Biology Analysis Expands the Spectrum of Causal Genes of Laterality Defects

Frontiers in Medicine, 2021
Laterality defects (LDs) or asymmetrically positioned organs are a group of rare developmental disorders caused by environmental and/or genetic factors. However, the exact molecular pathophysiology of LD is not yet fully characterised.
Rabab Said Alsafwani, Khalidah K. Nasser, Khalidah K. Nasser, Thoraia Shinawi, Babajan Banaganapalli, Babajan Banaganapalli, Hanan Abdelhalim ElSokary, Zhaher F. Zaher, Zhaher F. Zaher, Noor Ahmad Shaik, Noor Ahmad Shaik, Noor Ahmad Shaik, Gaser Abdelmohsen, Gaser Abdelmohsen, Jumana Yousuf Al-Aama, Jumana Yousuf Al-Aama, Adam J. Shapiro, Osman O. Al-Radi, Ramu Elango, Ramu Elango, Turki Alahmadi, Turki Alahmadi   +21 more
doaj   +1 more source

Organization of the Cytoskeleton in Ectopic Foci of the Endometrium with Rare Localization

Biomedicines, 2021
(1) Background: Endometriosis is a common pathology of the female reproductive system, often accompanied by pain and decreased fertility. However, its pathogenesis has not been sufficiently studied regarding the role of the cytoskeleton.
Konstantin A. Toniyan, Victoria V. Povorova, Elena Yu. Gorbacheva, Valery V. Boyarintsev, Irina V. Ogneva   +4 more
doaj   +1 more source