Results 101 to 110 of about 325,847 (336)

Studying breast cancer lung metastasis using a multi-compartment microfluidic device with a mimetic tumor-stroma interaction model

open access: yesTranslational Oncology
Background: Understanding the mechanisms underlying the metastasis of breast cancer cells to the lungs is challenging, and appropriate simulation of the tumor microenvironment with mimetic cancer-stroma crosstalk is essential.
Bahareh Zarin   +6 more
doaj   +1 more source

Code-division multiplexed resistive pulse sensor networks for spatio-temporal detection of particles in microfluidic devices

open access: yes, 2017
Spatial separation of suspended particles based on contrast in their physical or chemical properties forms the basis of various biological assays performed on lab-on-achip devices. To electronically acquire this information, we have recently introduced a
Asmare, Norh   +4 more
core   +1 more source

A centrifugo-magnetically actuated gas micropump [PDF]

open access: yes, 2006
This paper describes a novel gas micropump on a centrifugal microfluidic platform. The pump is integrated on a passive and microstructured polymer disk which is sealed with an elastomer lid featuring paramagnetic inlays.
Ducrée, Jens   +3 more
core   +1 more source

Peptide Sequencing With Single Acid Resolution Using a Sub‐Nanometer Diameter Pore

open access: yesAdvanced Functional Materials, EarlyView.
To sequence a single molecule of Aβ1−42–sodium dodecyl sulfate (SDS), the aggregate is forced through a sub‐nanopore 0.4 nm in diameter spanning a 4.0 nm thick membrane. The figure is a visual molecular dynamics (VMD) snapshot depicting the translocation of Aβ1−42–SDS through the pore; only the peptide, the SDS, the Na+ (yellow/green) and Cl− (cyan ...
Apurba Paul   +8 more
wiley   +1 more source

Sensor-Integrated Microfluidic Approaches for Liquid Biopsies Applications in Early Detection of Cancer

open access: yesSensors, 2020
Cancer represents one of the conditions with the most causes of death worldwide. Common methods for its diagnosis are based on tissue biopsies—the extraction of tissue from the primary tumor, which is used for its histological analysis.
Jessica Sierra   +4 more
doaj   +1 more source

Physical modelling of amorphous thermoplastic polymer and numerical simulation of micro hot embossing process [PDF]

open access: yes, 2017
Micro hot embossing process is considered as one of the most promising micro replication processes for manufacturing of polymeric components, especially for the high aspect ratio components and large surface structural components.
Barriere, T.   +3 more
core  

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

open access: yesAdvanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang   +9 more
wiley   +1 more source

A Programmable, 3D Neuron‐On‐Chip Platform Integrating Near Real‐Time Biosensing and Multiaxial Loading for Mechanobiological Injury Profiling

open access: yesAdvanced Science
Mechanical forces imparted to the central nervous system (CNS) generate complex, load‐dependent injury patterns, yet the molecular mechanisms linking physical insult to biomarker response remain poorly defined.
Sultan Khetani   +12 more
doaj   +1 more source

A Microfluidic Platform for Precision Small-volume Sample Processing and Its Use to Size Separate Biological Particles with an Acoustic Microdevice. [PDF]

open access: yes, 2015
A major advantage of microfluidic devices is the ability to manipulate small sample volumes, thus reducing reagent waste and preserving precious sample. However, to achieve robust sample manipulation it is necessary to address device integration with the
Benett, William J   +7 more
core   +1 more source

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