Results 91 to 100 of about 122,783 (311)

Rapid fabrication of polymer microfluidic systems for the production of artificial lipid bilayers

open access: yes, 2005
A polymer microfluidic device has been fabricated using rapid prototyping techniques. The device was built up to allow the formation and subsequent investigation of artificial bilayer lipid membranes (BLMs).
Morgan, H, Sandison, M E
core   +1 more source

On-chip inverted emulsion method for fast giant vesicle production, handling, and analysis

open access: yes, 2020
Liposomes and giant unilamellar vesicles (GUVs) in particular are excellent compartments for constructing artificial cells. Traditionally, their use requires bench-top vesicle growth, followed by experimentation under a microscope.
Robinson, T.   +2 more
core   +1 more source

Microfabricated Anisotropic Myobundles for the Scalable Production of Cardiac Tissue Grafts

open access: yesAdvanced Functional Materials, EarlyView.
Controlling the anisotropy of cardiac tissue remains an outstanding challenge in the field of cardiac tissue engineering. Here, we introduce an approach to generate anisotropic cardiac myobundles using cell‐adhesive, synthetic, electrospun fibers and stem cell‐derived cardiac fibroblasts.
Maggie E. Jewett   +15 more
wiley   +1 more source

Microsphere formation using SIFEL microfluidic devices with organic-solvent resistance

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2017
Biodegradable microspheres have been gathering attention as a promising controlled release drug delivery system (DDS), since they can administrate with one injection, dissolve in a body, release drugs over time, and do not need to remove after use.
Ikuko MORITA   +2 more
doaj   +1 more source

Optical imaging techniques in microfluidics and their applications [PDF]

open access: yes, 2012
Microfluidic devices have undergone rapid development in recent years and provide a lab-on-a-chip solution for many biomedical and chemical applications.
Lee, Lap Man, Wu, Jigang, Zheng, Guoan
core   +1 more source

Vorticity‐Driven µ‐Platelet Rotation and Selective Packing for Vertical Thermal–Electrical Interconnects

open access: yesAdvanced Functional Materials, EarlyView.
We introduce a capillary‐filtering‐based particle‐filling (CFPF) process that simultaneously forms vertical thermal pathways and electrical vias within µ‐pores. In situ microfluidic analysis reveals that capillary‐driven velocity gradients generate vorticity that governs µ‐platelet rotation and vertical alignment.
Yujin Mun   +11 more
wiley   +1 more source

Polydimethylsiloxane based microfluidic diode [PDF]

open access: yes, 2005
In this paper, we present a novel elastomer-based microfluidic device for rectifying flow. The device is analogous to an electronic diode in function since it allows flow in one direction and stops flow in the opposing direction. The device is planar, in-
Adams, M. L.   +3 more
core   +1 more source

Genipin‐Crosslinked, Silane‐Anchored 3D Tumor–Stroma Microtissues for High‐Content On‐Chip Drug Testing

open access: yesAdvanced Healthcare Materials, EarlyView.
We describe a microfluidic tumor‐stroma co‐culture model, engineered to resist collagen‐hydrogel contraction driven by fibroblast activity. Surface silanization with APTES covalently anchors the matrix to the chip, while Genipin crosslinking progressively increases stiffness and elasticity without harming cells. This supports >10 days of co‐culture and
Doriane Le Manach   +4 more
wiley   +1 more source

Investigation of the Influence of Glucose Concentration on Cancer Cells by Using a Microfluidic Gradient Generator without the Induction of Large Shear Stress

open access: yesMicromachines, 2016
A microfluidic device capable of precise chemical control is helpful to mimic tumor microenvironments in vitro, which are closely associated with malignant progression, including metastasis. Cancer cells under a concentration gradient of oxygen and other
Tadashi Ishida   +6 more
doaj   +1 more source

Metabolic Patterning on a Chip: Towards in vitro Liver Zonation of Primary Rat and Human Hepatocytes

open access: yes, 2018
An important number of healthy and diseased tissues shows spatial variations in their metabolic capacities across the tissue. The liver is a prime example of such heterogeneity where the gradual changes in various metabolic activities across the liver ...
Eo, Jinsu   +4 more
core   +2 more sources

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