Advanced Healthcare Materials, EarlyView.This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan +12 more
wiley +1 more source
, 2017 We present a regularized version of the color gradient lattice Boltzmann (LB) scheme for the simulation of droplet formation in microfluidic devices of experimental relevance.
La Rocca, Michele +6 more
core +1 more source
Photonic and Magnetic Force Micro-piston: An integrated force/microfluidic device for investigating expansion and compression stress in chromatin/chromosomes and their roles in chromosome function. [PDF]
, 2009 Jay K. Fisher +3 more
openalex +1 more source
Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction
Advanced Healthcare Materials, EarlyView.Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang +4 more
wiley +1 more source
Microfluidic Device to Measure Collective Force Dynamics of Kinesin Motor Proteins [PDF]
, 2018 Joseph M. Cleary, William O. Hancock
openalex +1 more source
AUTOMATED OOCYTE AND ZYGOTE DENUDATION USING A NOVEL MICROFLUIDIC DEVICE [PDF]
, 2020 Javier Guerrero Sánchez +11 more
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CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads
Advanced Healthcare Materials, EarlyView.In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura +4 more
wiley +1 more source
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Advanced Healthcare Materials, EarlyView.Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
A versatile and robust microfluidic device for capillary-sized simple or multiple emulsions production [PDF]
, 2018 Eliott Teston +6 more
openalex +1 more source
Passively driven microfluidic device with simple operation in the development of nanolitre droplet assay in nucleic acid detection [PDF]
, 2021 Pei-Heng Lin, Bor‐Ran Li
openalex +1 more source