Results 11 to 20 of about 122,783 (311)

Role of Polymers in Microfluidic Devices

open access: yesPolymers, 2022
Polymers are sustainable and renewable materials that are in high demand due to their excellent properties. Natural and synthetic polymers with high flexibility, good biocompatibility, good degradation rate, and stiffness are widely used for various applications, such as tissue engineering, drug delivery, and microfluidic chip fabrication.
Laila A. Damiati   +5 more
openaire   +5 more sources

Spheroid Engineering in Microfluidic Devices

open access: yesACS Omega, 2023
Two-dimensional (2D) cell culture techniques are commonly employed to investigate biophysical and biochemical cellular responses. However, these culture methods, having monolayer cells, lack cell-cell and cell-extracellular matrix interactions, mimicking the cell microenvironment and multicellular organization.
Atakan Tevlek   +4 more
openaire   +3 more sources

Genotyping with microfluidic devices [PDF]

open access: yesELECTROPHORESIS, 2006
AbstractIn the past few years, electrophoresis microchips have been increasingly utilized to interrogate genetic variations in the human and other genomes. Microfluidic devices can be readily applied to speed up existing genotyping protocols, in particular the ones that require electric field‐mediated separations in conjunction with restriction ...
Eszter, Szántai, András, Guttman
openaire   +2 more sources

Electroporation in Microfluidic Devices [PDF]

open access: yes, 2016
Crossing the plasma cellular membrane for loading of exogenous substances or accessing the intracellular medium is essential for cell engineering and transfection, cell analysis, or controlled extraction of the cellular content. Various chemical and physical techniques have been developed to open up the cell membrane and allow molecular exchange ...
Le Gac, Séverine, van Uitert, Iris
openaire   +3 more sources

Microfluidic Devices for Drug Assays [PDF]

open access: yesHigh-Throughput, 2018
In this review, we give an overview of the current state of microfluidic-based high-throughput drug assays. In this highly interdisciplinary research field, various approaches have been applied to high-throughput drug screening, including microtiter plate, droplets microfluidics as well as continuous flow, diffusion and concentration gradients-based ...
Clément Regnault   +2 more
openaire   +5 more sources

A novel, low-cost microfluidic device with an integrated filter for rapid, ultrasensitive, and high-throughput bioburden detection

open access: yesScientific Reports, 2023
Rapid and accurate bioburden detection has become increasingly necessary for food, health, pharmaceutical and environmental applications. To detect bioburden accurately, and in a highly sensitive manner, we have fabricated a novel microfluidic device ...
Md. Sadique Hasan   +6 more
doaj   +1 more source

Microfluidic Devices for Biomedical Applications: Biomedical Microfluidic Devices 2019 [PDF]

open access: yesMicromachines, 2020
Microfluidic devices and systems are well-suited for the manipulation of biomolecules, cells, or particles [...]
openaire   +3 more sources

Fluid Flow Shear Stress Stimulation on a Multiplex Microfluidic Device for Rat Bone Marrow Stromal Cell Differentiation Enhancement

open access: yesMicromachines, 2015
Microfluidic devices provide low sample consumption, high throughput, high integration, and good environment controllability advantages. An alternative to conventional bioreactors, microfluidic devices are a simple and effective platform for stem cell ...
Chia-Wen Tsao   +2 more
doaj   +1 more source

Liquid recirculation in microfluidic channels by the interplay of capillary and centrifugal forces [PDF]

open access: yes, 2009
We demonstrate a technique to recirculate liquids in a microfluidic device, maintaining a thin fluid layer such that typical diffusion times for analytes to reach the device surface are < 1 min.
Basabe-Desmonts, Lourdes   +4 more
core   +1 more source

Nanoadhesive layer to prevent protein absorption in a poly(dimethylsiloxane) microfluidic device

open access: yesBioTechniques, 2020
Poly(dimethylsiloxane) (PDMS) is widely used as a microfluidics platform material; however, it absorbs various molecules, perturbing specific chemical concentrations in microfluidic channels. We present a simple solution to prevent adsorption into a PDMS
Jae Bem You   +6 more
doaj   +1 more source

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