Results 11 to 20 of about 122,783 (311)
Role of Polymers in Microfluidic Devices
Polymers are sustainable and renewable materials that are in high demand due to their excellent properties. Natural and synthetic polymers with high flexibility, good biocompatibility, good degradation rate, and stiffness are widely used for various applications, such as tissue engineering, drug delivery, and microfluidic chip fabrication.
Laila A. Damiati +5 more
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Spheroid Engineering in Microfluidic Devices
Two-dimensional (2D) cell culture techniques are commonly employed to investigate biophysical and biochemical cellular responses. However, these culture methods, having monolayer cells, lack cell-cell and cell-extracellular matrix interactions, mimicking the cell microenvironment and multicellular organization.
Atakan Tevlek +4 more
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Genotyping with microfluidic devices [PDF]
AbstractIn the past few years, electrophoresis microchips have been increasingly utilized to interrogate genetic variations in the human and other genomes. Microfluidic devices can be readily applied to speed up existing genotyping protocols, in particular the ones that require electric field‐mediated separations in conjunction with restriction ...
Eszter, Szántai, András, Guttman
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Electroporation in Microfluidic Devices [PDF]
Crossing the plasma cellular membrane for loading of exogenous substances or accessing the intracellular medium is essential for cell engineering and transfection, cell analysis, or controlled extraction of the cellular content. Various chemical and physical techniques have been developed to open up the cell membrane and allow molecular exchange ...
Le Gac, Séverine, van Uitert, Iris
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Microfluidic Devices for Drug Assays [PDF]
In this review, we give an overview of the current state of microfluidic-based high-throughput drug assays. In this highly interdisciplinary research field, various approaches have been applied to high-throughput drug screening, including microtiter plate, droplets microfluidics as well as continuous flow, diffusion and concentration gradients-based ...
Clément Regnault +2 more
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Rapid and accurate bioburden detection has become increasingly necessary for food, health, pharmaceutical and environmental applications. To detect bioburden accurately, and in a highly sensitive manner, we have fabricated a novel microfluidic device ...
Md. Sadique Hasan +6 more
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Microfluidic Devices for Biomedical Applications: Biomedical Microfluidic Devices 2019 [PDF]
Microfluidic devices and systems are well-suited for the manipulation of biomolecules, cells, or particles [...]
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Microfluidic devices provide low sample consumption, high throughput, high integration, and good environment controllability advantages. An alternative to conventional bioreactors, microfluidic devices are a simple and effective platform for stem cell ...
Chia-Wen Tsao +2 more
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Liquid recirculation in microfluidic channels by the interplay of capillary and centrifugal forces [PDF]
We demonstrate a technique to recirculate liquids in a microfluidic device, maintaining a thin fluid layer such that typical diffusion times for analytes to reach the device surface are < 1 min.
Basabe-Desmonts, Lourdes +4 more
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Nanoadhesive layer to prevent protein absorption in a poly(dimethylsiloxane) microfluidic device
Poly(dimethylsiloxane) (PDMS) is widely used as a microfluidics platform material; however, it absorbs various molecules, perturbing specific chemical concentrations in microfluidic channels. We present a simple solution to prevent adsorption into a PDMS
Jae Bem You +6 more
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