Results 11 to 20 of about 132,158 (308)

A surface-engineered microfluidic device for antibody-mediated negative selection of high-quality sperm for assisted reproduction

Advanced Functional Materials, EarlyView.
This study reports a microfluidic device with a functionalized surface utilizing a polyoxazoline coating and covalently immobilized gold nanoparticles and anti‐phosphatidylserine antibody. The device efficiently eliminates pre‐apoptotic and apoptotic spermatozoa and yields sperm with substantially improved quality and low DNA damage, offering a simple ...
Ghaemi SR, Sharkey DJ, McPherson NO, Alemie MN, Vasilev K, Robertson SA.   +5 more
europepmc   +2 more sources

Elastomeric microfluidic diode and rectifier work with Newtonian fluids [PDF]

, 2009
We report on two microfluidic elastomeric autoregulatory devices—a diode and a rectifier. They exhibit physically interesting and complex nonlinear behaviors (saturation, bias-dependent resistance, and rectification) with a Newtonian fluid.
Chen, Yan, Kartalov, Emil P., Liu, John, Scherer, Axel, Taylor, Clive R.   +4 more
core   +1 more source

An all-glass microfluidic network with integrated amorphous silicon photosensors for on-chip monitoring of enzymatic biochemical assay [PDF]

, 2017
A lab-on-chip system, integrating an all-glass microfluidics and on-chip optical detection, was developed and tested. The microfluidic network is etched in a glass substrate, which is then sealed with a glass cover by direct bonding.
Caputo, Domenico, Costantini, Francesca, de Cesare, Giampiero, Gardeniers, Han J. G. E., Manetti, Cesare, Nardecchia, Marco, Nascetti, Augusto, Salvio, Riccardo, Schlautmann, Stefan, Tiggelaar, Roald M.   +9 more
core   +5 more sources

Genotyping with microfluidic devices [PDF]

ELECTROPHORESIS, 2006
AbstractIn the past few years, electrophoresis microchips have been increasingly utilized to interrogate genetic variations in the human and other genomes. Microfluidic devices can be readily applied to speed up existing genotyping protocols, in particular the ones that require electric field‐mediated separations in conjunction with restriction ...
Eszter, Szántai, András, Guttman
openaire   +2 more sources

A Microfluidic Platform for Precision Small-volume Sample Processing and Its Use to Size Separate Biological Particles with an Acoustic Microdevice. [PDF]

, 2015
A major advantage of microfluidic devices is the ability to manipulate small sample volumes, thus reducing reagent waste and preserving precious sample. However, to achieve robust sample manipulation it is necessary to address device integration with the
Benett, William J, Bora, Mihail, Burklund, Alison, Fong, Erika J, Hamilton, Julie, Huang, Chao, Metz, Thomas R, Shusteff, Maxim   +7 more
core   +1 more source

Microfluidic immunomagnetic multi-target sorting – a model for controlling deflection of paramagnetic beads [PDF]

, 2011
We describe a microfluidic system that uses a magnetic field to sort paramagnetic beads by deflecting them in the direction normal to the flow. Our experiments systematically study the dependence of the beads’ deflection on: bead size and susceptibility,
Griffiths, I. M., Stone, H. A., Tsai, S. S. H.   +2 more
core   +2 more sources

Silk Fibroin Microfluidic Devices [PDF]

Advanced Materials, 2007
Precisely controlling spatio-temporal environmental parameters has become increasingly important in the field of biotechnology. For this reason, biomedical research has increasingly moved toward the design and implementation of microfabricated systems to efficiently improve technologies such as drug delivery,[1] diagnostics,[2] and tissue engineering ...
Christopher J, Bettinger, Kathleen M, Cyr, Akira, Matsumoto, Robert, Langer, Jeffrey T, Borenstein, David L, Kaplan   +5 more
openaire   +2 more sources

Multimode interference devices for focusing in microfluidic channels [PDF]

, 2011
Low-cost, compact, automated optical microsystems for chemical analysis, such as microflow cytometers for identification of individual biological cells, require monolithically integrated microlenses for focusing in microfluidic channels, to enable high ...
Ateya, Camou, Dongre, Godin, Hamish C. Hunt, Hunt, James S. Wilkinson, Moreno, Seo, Soldano   +9 more
core   +1 more source

Microfluidic DNA amplification - a review [PDF]

, 2009
The application of microfluidic devices for DNA amplification has recently been extensively studied. Here, we review the important development of microfluidic polymerase chain reaction (PCR) devices and discuss the underlying physical principles for the ...
Ozdemir, Pinar, Zhang, Yonghao
core   +1 more source

Spheroid Engineering in Microfluidic Devices

ACS Omega, 2023
Two-dimensional (2D) cell culture techniques are commonly employed to investigate biophysical and biochemical cellular responses. However, these culture methods, having monolayer cells, lack cell-cell and cell-extracellular matrix interactions, mimicking the cell microenvironment and multicellular organization.
Atakan Tevlek, Seren Kecili, Ozge S. Ozcelik, Haluk Kulah, H. Cumhur Tekin   +4 more
openaire   +3 more sources