Activation and Expansion of Human T-Cells Using Microfluidic Devices. [PDF]
Peñaherrera-Pazmiño AB +8 more
europepmc +1 more source
A Microcapsule‐Integrated smRandom‐seq Platform Enables Fixation‐Free Single Microbe RNA Sequencing
We developed a microcapsule‐integrated high‐throughput fixation‐free single‐microbe RNA‐seq workflow in which microbes are encapsulated in aqueous two‐phase microcapsules for physical confinement of nucleic acids. This platform enables co‐encapsulation with barcoded beads for sequencing and reveals that fixation‐free processing enhances transcriptomic ...
Mengdi Song +5 more
wiley +1 more source
Present and future of smart functional materials as actuators in microfluidic devices.
Izaddoust S +7 more
europepmc +1 more source
On Using Electric Circuit Models to Analyze Electric Field Distributions in Insulator-Based Electrokinetically Driven Microfluidic Devices. [PDF]
de Los Santos-Ramirez JM +3 more
europepmc +1 more source
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie +10 more
wiley +1 more source
Thermoregulable Magnetic Microfluidic Devices by Magnetic Hyperthermia from Iron Oxide Nanoparticles. [PDF]
Parames-Estevez S +6 more
europepmc +1 more source
Spatially Encoded Protocell Network for Non‐Cascaded Parallel Biocomputation
A non‐cascaded, hydrogel‐based proteinosome computational platform is developed, in which redox‐responsive proteinosomes serve as local computing units within a shared reaction–diffusion field. Reductant inputs, countered by an auxiliary glucose gradient, regulate spatially patterned proteinosome disruption, and generate population‐level boundaries ...
Shuqi Wu, Liangfei Tian
wiley +1 more source
Mass fabrication of PDMS microfluidic devices by injection molding and applications in sensitive 3D spheroid and explant culture. [PDF]
Filion R +9 more
europepmc +1 more source
Machine Learning of Temperature‐Dependent Chemical Kinetics Using Parallel Droplet Microreactors
An integrated droplet microfluidics and machine learning framework enables high‐throughput characterization of temperature‐dependent reaction kinetics. Time‐resolved measurements from thousands of droplets train Neural ODE models that accurately predict nonlinear reaction dynamics across diverse thermal environments, bridging large‐scale ...
Mamoru Saita, Yutaka Hori
wiley +1 more source

