Results 61 to 70 of about 108,267 (322)
Bioprocess microfluidics: applying microfluidic devices for bioprocessing
Current Opinion in Chemical Engineering, 2017 Scale-down approaches have long been applied in bioprocessing to resolve scale-up problems. Miniaturized bioreactors have thrived as a tool to obtain process relevant data during early-stage process development. Microfluidic devices are an attractive alternative in bioprocessing development due to the high degree of control over process variables ...
Marco P.C. Marques, Nicolas Szita
openaire +3 more sources
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
A semi-automated, field-portable microscopy platform for clinical diagnostic applications
AIP Advances, 2015 Clinical microscopy is a versatile diagnostic platform used for diagnosis of a multitude of diseases. In the recent past, many microfluidics based point-of-care diagnostic devices have been developed, which serve as alternatives to microscopy.
Veerendra Kalyan Jagannadh +2 more
doaj +1 more source
Alginate Bead Biosystem for the Determination of Lactate in Sweat Using Image Analysis
Biosensors, 2021 Lactate is present in sweat at high concentrations, being a metabolite of high interest in sport science and medicine. Therefore, the potential to determine lactate concentrations in physiological fluids, at the point of need with minimal invasiveness ...
Sandra Garcia-Rey +4 more
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, 2018 Objectives: During recent years, microgels have emerged as an effective type of drug delivery system (DDS), due to their tuneable size, increased surface area and injectability. The current study focuses on the use of microfluidic techniques for the generation of monodisperse type-I collagen (col-I) microgels crosslinked with PEG-4S, encapsulating ...
Rey, Jose M. +4 more
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FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
A New Paper-Based Microfluidic Device for Improved Detection of Nitrate in Water
Sensors, 2020 In this paper, we report a simple and inexpensive paper-based microfluidic device for detecting nitrate in water. This device incorporates two recent developments in paper-based technology suitable for nitrate detection and has an optimized microfluidic ...
Amer Charbaji +3 more
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Biosensors, 2023 In recent years, innovative cell-based biosensing systems have been developed, showing impact in healthcare and life science research. Now, there is a need to design mass-production processes to enable their commercialization and reach society.
Enrique Azuaje-Hualde +7 more
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Nature Communications, 2022 Anti-cancer cytotoxic T cell responses largely vary among individuals. Here authors show, by stochastic modeling on high throughput T cell behavior and matched tumor spheroid fate data generated by a microfluidics system, that tumor killing is dependent ...
Gustave Ronteix +6 more
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Biosensors, 2023 In this paper, we present a novel and cost-effective lab-on-paper microfluidics platform for performing ELISA autonomously, with no user intervention beyond adding the sample.
Hojat Heidari-Bafroui +7 more
doaj +1 more source