Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix
Advanced Functional Materials, EarlyView.Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt +2 more
wiley +1 more source
Predicting Dimensions in Microfluidic Paper Based Analytical Devices
Sensors, 2020 The main problem for the expansion of the use of microfluidic paper-based analytical devices and, thus, their mass production is their inherent lack of fluid flow control due to its uncontrolled fabrication protocols.
Raquel Catalan-Carrio +3 more
doaj +1 more source
DNA-coated Functional Oil Droplets
, 2017 Many industrial soft materials often include oil-in-water (O/W) emulsions at the core of their formulations. By using tuneable interface stabilizing agents, such emulsions can self-assemble into complex structures.
Bruns, Nico +8 more
core +2 more sources
High-sensitivity microfluidic calorimeters for biological and chemical applications [PDF]
, 2009 High-sensitivity microfluidic calorimeters raise the prospect of achieving high-throughput biochemical measurements with minimal sample consumption. However, it has been challenging to realize microchip-based calorimeters possessing both high sensitivity
B. W. Axelrod +13 more
core +3 more sources
Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Advanced Functional Materials, EarlyView.Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
Automated Microfluidic Platform for Molecular Transport Analysis across Biomimetic Interfaces
Advanced Sensor ResearchAdvancing drug development and disease modeling requires physiologically relevant in vitro systems that accurately reproduce the dynamic and selective transport functions of human tissue barriers.
Olivier Fournier +12 more
doaj +1 more source
Experimental studies on 3D printing of barium titanate ceramics for medical applications
Current Directions in Biomedical Engineering, 2016 The present work deals with the 3D printing of porous barium titanate ceramics. Barium titanate is a biocompatible material with piezoelectric properties.
Schult Mark, Buckow Eric, Seitz Hermann
doaj +1 more source
A reverse predictive model towards design automation of microfluidic droplet generators [PDF]
, 2018 This work has been presented in the 10th IWBDA workshop.Droplet-based microfluidic devices in comparison to test tubes can reduce reaction volumes 10^9 times and more due to the encapsulation of reactions in micro-scale droplets [4].
Douglas, Densmore +2 more
core
Microwave Dielectric Heating of Drops in Microfluidic Devices [PDF]
, 2009 We present a technique to locally and rapidly heat water drops in microfluidic devices with microwave dielectric heating. Water absorbs microwave power more efficiently than polymers, glass, and oils due to its permanent molecular dipole moment that has ...
Brown, Keith A. +5 more
core +2 more sources
Biomimetic Iridescent Skin: Robust Prototissues Spontaneously Assembled from Photonic Protocells
Advanced Functional Materials, EarlyView.Uniform nanoparticles are induced to form arrays (photonic crystals) in the cores of biopolymer capsules, endowing these ‘protocells’ with structural color. These protocells are then assembled into large self‐standing objects, i.e., prototissues, with robust mechanical properties as well as iridescent optical properties.
Medha Rath +6 more
wiley +1 more source