Results 261 to 270 of about 315,527 (297)
Some of the next articles are maybe not open access.
CNS & Neurological Disorders - Drug Targets, 2011
Microglia, the tissue macrophages of the brain, have under healthy conditions a resting phenotype that is characterized by a ramified morphology. With their fine processes microglia are continuously scanning their environment. Upon any homeostatic disturbance microglia rapidly change their phenotype and contribute to processes including inflammation ...
Olah, M +3 more
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Microglia, the tissue macrophages of the brain, have under healthy conditions a resting phenotype that is characterized by a ramified morphology. With their fine processes microglia are continuously scanning their environment. Upon any homeostatic disturbance microglia rapidly change their phenotype and contribute to processes including inflammation ...
Olah, M +3 more
openaire +3 more sources
2019
Microglial cells derive from fetal macrophages which immigrate into and disseminate throughout the central nervous system (CNS) in early embryogenesis. After settling in the nerve tissue, microglial progenitors acquire an idiosyncratic morphological phenotype with small cell body and moving thin and highly ramified processes currently defined as ...
Garaschuk, Olga, Verkhratsky, Alexei
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Microglial cells derive from fetal macrophages which immigrate into and disseminate throughout the central nervous system (CNS) in early embryogenesis. After settling in the nerve tissue, microglial progenitors acquire an idiosyncratic morphological phenotype with small cell body and moving thin and highly ramified processes currently defined as ...
Garaschuk, Olga, Verkhratsky, Alexei
openaire +4 more sources
Neuropharmacology
TREM2 is a membrane receptor solely expressed on microglia in normal brain. In this review we outline recent advances in TREM2 biology and its implications for microglial function, with particular emphasis on findings from iPSC-derived microglia (iMG) expressing TREM2 loss-of-function mutations.
Jennifer Pocock +3 more
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TREM2 is a membrane receptor solely expressed on microglia in normal brain. In this review we outline recent advances in TREM2 biology and its implications for microglial function, with particular emphasis on findings from iPSC-derived microglia (iMG) expressing TREM2 loss-of-function mutations.
Jennifer Pocock +3 more
openaire +3 more sources
2019
Dark microglia, a recently described phenotype, are found in high numbers in nonhomeostatic conditions (e.g., Alzheimer's disease pathology, aging, chronic stress). As a specific protein marker has not yet been defined, they cannot be studied using conventional cellular biology techniques.
Marie-Kim, St-Pierre +2 more
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Dark microglia, a recently described phenotype, are found in high numbers in nonhomeostatic conditions (e.g., Alzheimer's disease pathology, aging, chronic stress). As a specific protein marker has not yet been defined, they cannot be studied using conventional cellular biology techniques.
Marie-Kim, St-Pierre +2 more
openaire +2 more sources
Microglia in neuroregeneration
Microscopy Research and Technique, 2001AbstractMicroglia has the potential to produce and release a range of factors that directly and/or indirectly promote regeneration in the injured nervous system. The overwhelming evidence indicates, however, that this potential is generally not expressed in vivo.
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Microglia regulate central nervous system myelin growth and integrity
Nature, 2022Niamh McNamara +2 more
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Negative feedback control of neuronal activity by microglia
Nature, 2020Ana Badimon, Pinar Ayata, Xinhong Chen
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