Results 281 to 290 of about 388,044 (340)

Methodologies for Sample Multiplexing and Computational Deconvolution in Single‐Cell Sequencing

Advanced Science, EarlyView.
Sample multiplexing offers a critical solution for boosting throughput and minimizing batch effects in single‐cell sequencing. This review navigates the latest experimental methodologies and computational deconvolution algorithms, bridging the gap between wet‐lab design and analytical success.
Yufei Gao, Weiwei Yin, Wei Hu, Wei Chen
wiley   +1 more source

The Parkinson's disease-associated LRRK2-G2019S variant restricts serine metabolism, leading to microglial inflammation and dopaminergic neuron degeneration. [PDF]

J Neuroinflammation
Kurniawan H, Nickels SL, Zagare A, Zuccoli E, Rosety I, Gomez-Giro G, Glaab E, Schwamborn JC.   +7 more
europepmc   +1 more source

Microglia in Physiology and Disease.

Annual Review of Physiology, 2017
S. Wolf, H. Boddeke, H. Kettenmann
semanticscholar   +1 more source

Disordered Glass Nanowire Substrates Produce in Vivo‐Like Astrocyte Morphology Revealed by Low‐Coherence Holotomography

Advanced Science, EarlyView.
Low‐coherence holotomography reveals that disordered nanowire substrates guide astrocyte morphology toward branched, in vivo–like star‐shaped morphology, emphasizing the role of biophysical cues in shaping neural cell behavior. The developed nanostructured platform offers a new route to study astrocytes for neurobiology studies. Abstract Astrocytes are
Pooja Anantha, Anoushka Gupta, Joo Ho Kim, Emanuela Saracino, Piyush Raj, Ivano Lucarini, Swati Tanwar, Jessica Chen, Luo Gu, Jay Agrawal, Annalisa Convertino, Ishan Barman   +11 more
wiley   +1 more source

RNA-binding protein IMP1/ZBP1 directs local translation in microglial processes to regulate motility and phagocytosis during inflammation. [PDF]

PLoS Biol
Imaz-Iruretagoyena J, Blanco-Urrejola M, Núñez-García I, García-Toledo I, Fernández-Beltrán LC, Márquez M, Corrochano S, Sierra A, Baleriola J.   +8 more
europepmc   +1 more source

Additional file 1: of Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimerâ s disease-related proteins

, 2018
Srikant Rangaraju, Eric B. Dammer, Syed Ali Raza, Tianwen Gao, Hailian Xiao, Ranjita Betarbet, Duc M. Duong, James Webster, Chadwick M. Hales, James J. Lah, Allan I. Levey, Nicholas T. Seyfried   +11 more
openalex   +1 more source

Fever Inspiration: Precision Engineering for Safe and Systemic Immunotherapy

Advanced Science, EarlyView.
This review examines engineered fever therapy (EFT) as a novel cancer treatment, harnessing fever's immunomodulatory effects to enhance systemic immune responses. It explores molecular mechanisms, advances in nanotechnology‐driven thermal immunotherapy, and a bioengineered framework for precise, safe fever induction. The paper evaluates EFT's potential
Yang Li, Fulong Man, Jianwei Cheng, Li Chen, Yongyong Li, Haiqing Dong   +5 more
wiley   +1 more source

Neuroprotection and Axonal Regeneration via ECM‐Mimetic Nanofibers Incorporating Metal–Phenolic Network Nanoparticles Toward Spinal Cord Injury Repair

Advanced Science, EarlyView.
Metal–phenolic network (MPN) nanoparticles with neuroprotective functions are integrated into decellularized extracellular matrix (dECM) to obtain biomimetic composite fibrous scaffold MPN@dECM NFs by electrospinning, which protects spared neurons from secondary degeneration by suppressing excitotoxicity and inflammation, and promotes directional ...
Shu Chen, Bixue Wang, Qiya Zhang, Changsheng Liu, Xi Chen   +4 more
wiley   +1 more source

Global research hotspots and trends in microglia in ischemic stroke. [PDF]

Front Immunol
Liu Y, Ye Y, Dai F, Bai L, Ji H, Su X, Hu P, Cheng H.   +7 more
europepmc   +1 more source