Results 91 to 100 of about 58,777 (326)

Drug delivery pathways to the central nervous system via the brain glymphatic system circumventing the blood‐brain barrier

Exploration, EarlyView.
The discovery of the glymphatic system has opened up a pathway for drug delivery to the brain by circumventing the blood‐brain barrier, which can effectively improve drug utilization. The methods of drug delivery through the glymphatic system include intrathecal injection, intranasal injection, and delivery through the meningeal lymphatic vessels.
Xiang Wang, Yue Yin, Huaijuan Zhou, Bowen Chi, Ling Guan, Pei Li, Jinhua Li, Yilong Wang   +7 more
wiley   +1 more source

Investigation on the Band Gap and Negative Properties of Concentric Ring Acoustic Metamaterial

Shock and Vibration, 2018
The acoustic characteristics of 2D single-oscillator, dual-oscillator, and triple-oscillator acoustic metamaterials were investigated based on concentric ring structures using the finite element method.
Meng Chen, Dan Meng, Heng Jiang, Yuren Wang   +3 more
doaj   +1 more source

The Study of the Mechanism of Protein Crystallization in Space by Using Microchannel to Simulate Microgravity Environment

Crystals, 2018
Space is expected to be a convection-free, quiescent environment for the production of large-size and high-quality protein crystals. However, the mechanisms by which the diffusion environment in space improves the quality of the protein crystals are not ...
Yong Yu, Kai Li, Hai Lin, Ji-Cheng Li
doaj   +1 more source

A Simulated Microgravity Environment Causes a Sustained Defect in Epithelial Barrier Function. [PDF]

, 2019
Intestinal epithelial cell (IEC) junctions constitute a robust barrier to invasion by viruses, bacteria and exposure to ingested agents. Previous studies showed that microgravity compromises the human immune system and increases enteropathogen virulence.
Alvarez, Rocio, Marchelletta, Ronald R, McCole, Declan F, Prisk, G Kim, Sayoc-Becerra, Anica, Stork, Cheryl A   +5 more
core   +1 more source

Microalgae: A Solution for Food Security and Multiplanetary Farming

Food Frontiers, EarlyView.
ABSTRACT Human civilization is threatened by food insecurity and habitat loss owing to the cumulative effects of anthropogenic and natural factors. Thus, increasing food production while using fewer resources and exploring the potential of interstellar migration is essential.
Xiulan Xie, Jiasui Zhan, Maozhi Ren
wiley   +1 more source

Direct mechanical exposure initiates hepatocyte proliferation

JHEP Reports, 2023
Background & Aims: Liver paracrine signaling from liver sinusoid endothelial cells to hepatocytes in response to mechanical stimuli is crucial in highly coordinated liver regeneration.
Wang Li, Yi Wu, Wenhui Hu, Jin Zhou, Xinyu Shu, Xiaoyu Zhang, Ziliang Zhang, Huan Wu, Yu Du, Dongyuan Lü, Shouqin Lü, Ning Li, Mian Long   +12 more
doaj  

3D cell culture model: From ground experiment to microgravity study

Frontiers in Bioengineering and Biotechnology, 2023
Microgravity has been shown to induce many changes in cell growth and differentiation due to offloading the gravitational strain normally exerted on cells.
Chiyuan Ma, Chiyuan Ma, Xianglong Duan, Xianglong Duan, Xiaohua Lei   +4 more
doaj   +1 more source

Spaceflight redefines ageing‐associated microbiota

iMeta, EarlyView.
Spaceflight reshapes microbiota and immune function, mitigating some ageing effects while accelerating immune aging, revealing crucial insights for astronaut health and longevity in space missions.
Yuan Sun, Sai Liu, Long Chen, Zheng Zhou, Mengyu Ma, Jinran Li, Yi Lu, Yiting Shi, Tingting Yao, Ruizhi Feng, Qiulun Lu, Fatimah Qassadi, Philip M. Williams, Tanya M. Monaghan, Guangji Wang, Zheying Zhu, Xinuo Li   +16 more
wiley   +1 more source

Blood flow and microgravity

Comptes Rendus. Mécanique, 2016
AbstractThe absence of gravity during space flight can alter cardio-vascular functions partially due to reduced physical activity. This affects the overall hemodynamics, and in particular the level of shear stresses to which blood vessels are submitted.
Lionel Bureau, Lionel Bureau, Frank Dubois, Chaouqi Misbah, Chaouqi Misbah, Thomas Podgorski, Thomas Podgorski, Daria Tsvirkun, Alain Duperray, Alain Duperray, Christophe Minetti, Alexander Farutin, Alexander Farutin, Gwennou Coupier, Gwennou Coupier, Mikhail Vysokikh   +15 more
openaire   +4 more sources

Spatiotemporal Intermittency in Pulsatile Pipe Flow

Entropy, 2020
Despite its importance in cardiovascular diseases and engineering applications, turbulence in pulsatile pipe flow remains little comprehended. Important advances have been made in the recent years in understanding the transition to turbulence in such ...
Daniel Feldmann, Daniel Morón, Marc Avila   +2 more
doaj   +1 more source