Results 271 to 280 of about 28,349 (334)

Cytotransducers for Visualization of Spatiotemporal Intercellular Communication

Small, Volume 21, Issue 35, September 4, 2025.
Cytotransducers are constructed to visualize intercellular communication based on the spatiotemporally controlled intervention of nanometer‐sized artifacts as stable tracers. The designed cytotransducer is 110 nm in size and composed of a lipid membrane and fluorescent nanodiamond.
Niko Kimura, Yoko Yamanishi, Shinya Sakuma   +2 more
wiley   +1 more source

Endothelin‐Converting Enzyme‐Like 1 Regulated by LIF Contributes to Chronic Constriction Injury‐Induced Neuropathic Pain in Mice

CNS Neuroscience &Therapeutics, Volume 31, Issue 9, September 2025.
After chronic constriction injury (CCI), leukemia inhibitory factor (LIF) is transported from the distal injury site to dorsal root ganglion (DRG) neurons and promotes the expression of ECEL1, thereby promoting sympathetic sprouting and causing neuropathic pain. ABSTRACT Aims This study is to investigate the role of Endothelin‐converting enzyme‐like 1 (
Feng Gao, Yuchen Pan, Yong Huang, Chen Gu, Xiaowei Song, Cunjin Wang   +5 more
wiley   +1 more source

Generating and Validating Transgenic Mosquitoes with Transposon-Mediated Transgenesis. [PDF]

Cold Spring Harb Protoc
Bottino-Rojas V, James AA.
europepmc   +1 more source

GPD1L‐Mediated Glycerophospholipid Metabolism Dysfunction in Women With Diminished Ovarian Reserve: Insights From Pseudotargeted Metabolomic Analysis of Follicular Fluid

Cell Proliferation, Volume 58, Issue 9, September 2025.
Our study demonstrated the downregulation of GPD1L and its mediated glycerophospholipid metabolism dysfunction in patients with diminished ovarian reserve. Moreover, we verified that GPD1L knockdown leads to increased cell apoptosis and mitochondrial dysfunction of KGN cells, as well as impaired oocyte quality.
Jiaqi Wu, Xuehan Zhao, Ying Fang, Cong Wang, Yichang Tian, Wan Tu, Qiqian Wu, Long Yan, Xiaokui Yang   +8 more
wiley   +1 more source

High-throughput genetic manipulation of multicellular organisms using a machine-vision guided embryonic microinjection robot. [PDF]

Genetics
Alegria AD, Joshi AS, Mendana JB, Khosla K, Smith KT, Auch B, Donovan M, Bischof J, Gohl DM, Kodandaramaiah SB.   +9 more
europepmc   +1 more source

Unraveling the functional dynamics of Caenorhabditis elegans stress‐responsive omega class GST‐44

The FEBS Journal, Volume 292, Issue 17, Page 4675-4693, September 2025.
Omega‐class glutathione S‐transferases (GSTs) are integral to redox regulation and cellular stress responses. This study characterized GST‐44 in Caenorhabditis elegans, revealing its predominant expression in the intestine and excretory H‐cell, with significant upregulation under various stress conditions.
Charlotte Sophia Kaiser, Milena Lubisch, Emma Schröder, Luka Ressmann, Marie Nicolaus, Dustin Leusder, Sven Moyzio, Robert Peuss, Antonio Miranda‐Vizuete, Eva Liebau   +9 more
wiley   +1 more source

Brain stimulation preferentially influences long-range projections. [PDF]

Sci Adv
Vieira PG, Krause MR, Laamerad P, Pack CC.   +3 more
europepmc   +1 more source

Splanchnic and Pelvic Spinal Afferent Pathways Relay Sensory Information From the Mouse Colorectum Into Distinct Brainstem Circuits

Journal of Neurochemistry, Volume 169, Issue 9, September 2025.
This study used transneuronal viral tracer to identify the spinal cord and brainstem circuits connected to the colorectum in the mouse (A). To establish if the regions of the brainstem labelled from the colon were functionally relevant to colorectal sensory‐motor processing, the distribution of neurons activated by distending the colon was mapped (B ...
QingQing Wang, Alice E. McGovern, Melinda Kyloh, Grigori Rychkov, Nick J. Spencer, Stuart B. Mazzone, Stuart M. Brierley, Andrea M. Harrington   +7 more
wiley   +1 more source

Microparticle Bombardment as a Method for Transgenesis in <i>Auanema</i> and <i>Tokorhabditis</i>. [PDF]

MicroPubl Biol
Yamashita T, Pires-daSilva A, Oomura S, Kusano T, Haruta N, Hasumi M, Kikuchi T, Adams S, Sugimoto A, Shinya R.   +9 more
europepmc   +1 more source

The Neuropathology of Alcohol Use Disorder: Cellular Insights From Human Post‐Mortem Studies

Journal of Neurochemistry, Volume 169, Issue 9, September 2025.
Major cellular changes in alcohol use disorder human post‐mortem brain. Alcohol use disorder (AUD) is a complex neurological disorder that undergoes neural changes, mainly degeneration and or cellular alterations impacting addiction behaviours. Key brain regions implicated in AUD are the cortex, striatum, corpus callosum, hippocampus, hypothalamus ...
Ameer E. Rasool, Jennifer L. Cornish, Asheeta A. Prasad   +2 more
wiley   +1 more source