Results 291 to 300 of about 51,233 (376)

LRP4+ Astrocytes: A Unique Subpopulation Crucial for Blood Vessel Maintenance and Function in the Somatosensory Cortex of Normal and 5xFAD Mice

open access: yesGlia, Volume 74, Issue 2, February 2026.
Lrp4+ astrocytes, uniquely vessel‐associated and GFAP−, are enriched in the pia. They support laminin‐α5+ basement membrane assembly and regulate vessel diameter and blood flow. They are reduced in 5xFAD brains, and their ablation worsens both vascular and Aβ pathology.
Emily Arzola   +10 more
wiley   +1 more source

Uncovering the neural control of laryngeal activity and subglottic pressure in anaesthetized rats: insights from mesencephalic regions. [PDF]

open access: yesPflugers Arch
González-García M   +6 more
europepmc   +1 more source

The ZNF148‐ZEB1‐AS1‐IGF2BP2‐NOD2 Axis Drives Microglial Antipneumococcal Immunity in Bacterial Meningitis

open access: yesGlia, Volume 74, Issue 2, February 2026.
ZNF148 upregulates ZEB1‐AS1, which scaffolds IGF2BP2 to stabilize NOD2 mRNA, enhancing microglial anti‐pneumococcal immunity via cytokine production and bacterial clearance in bacterial meningitis. ABSTRACT Streptococcus pneumoniae (Spn) meningitis remains a lethal central nervous system (CNS) infection with limited therapies. This study identifies the
Xiufu Hu   +6 more
wiley   +1 more source

Annexin A2 Causes Motor Incoordination via Muscle–Cerebellum Axis in Sarcopenia

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Sarcopenia is a prevalent age‐related disorder characterized by progressive muscle atrophy. Impaired balance is one of its most critical clinical consequences, often leading to falling and even bone fractures. As the cerebellum plays a central role in regulating motor coordination, elucidating the molecular mechanisms underlying ...
Xin Jiao   +16 more
wiley   +1 more source

The Calcium‐Binding Protein S100A10 (p11) Is Required for Normal Motor Performance by Regulating Vesicle Dynamics at Excitatory Synapses

open access: yesActa Physiologica, Volume 242, Issue 2, February 2026.
ABSTRACT Aim Identifying interactors in sensorimotor processing and neurotransmission remains a current challenge for understanding neural information processing and brain function. Methods To evaluate the role of p11 in sensorimotor processing and excitatory synaptic neurotransmission, neuron‐specific lentivirus‐directed p11 silencing, small ...
Esther Vilches‐Herrando   +7 more
wiley   +1 more source

SYNCAS‐mediated CRISPR‐Cas9 genome editing in the Jewel wasp, Nasonia vitripennis

open access: yesInsect Molecular Biology, Volume 35, Issue 1, Page 48-55, February 2026.
Maternal injection of Cas9 RNP together with BAPC and saponins (SYNCAS) results in efficient gene editing of Nasonia vitripennis offspring. The timing of injection and egg collection is important for maximising efficiency and reducing screening effort.
Filippo Guerra   +2 more
wiley   +1 more source

Tranexamic Acid for Hyperpigmentation Disorders: A Literature Review on Efficacy and Safety in Melasma and PIH

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 2, February 2026.
ABSTRACT Background Hyperpigmentation disorders, including melasma and post‐inflammatory hyperpigmentation (PIH), are common dermatologic conditions associated with significant cosmetic and psychological burden. Tranexamic acid (TXA), an antifibrinolytic agent, has gained increasing attention due to its anti‐inflammatory and antimelanogenic properties.
Ahmed AlJabr   +2 more
wiley   +1 more source

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