Results 71 to 80 of about 51,233 (376)

Systemic and Intra-Habenular Activation of the Orphan G Protein-Coupled Receptor GPR139 Decreases Compulsive-Like Alcohol Drinking and Hyperalgesia in Alcohol-Dependent Rats. [PDF]

, 2018
GPR139 is an orphan G protein-coupled receptor (GPCR) that is expressed mainly in the brain, with the highest expression in the medial habenula. The modulation of GPR139 receptor function has been hypothesized to be beneficial in the treatment of some ...
Conlisk, Dana, de Guglielmo, Giordano, George, Olivier, Kallupi, Marsida, Kimbrough, Adam, Kononoff, Jenni   +5 more
core  

Effect of scopolamine-based amnesia on the number of astrocytes in the rat's hippocampus [PDF]

, 2012
As neuron-astrocyte interactions play a crucial role in the adult brain, it is thought that astrocytes support learning and memory through specific mechanisms.
Azami, N.S., Jahanshahi, M., Nickmahzar, E.   +2 more
core   +1 more source

Thermally Drawn Multifunctional All‐Hydrogel Fibers for Anti‐Fibrotic and Multimodal Neural Interfaces

Advanced Materials, EarlyView.
Hydrogels demonstrate material properties that mimic the mechanical and chemical environments of biological tissues. Yet, they face challenges during their integration into 3D interfaces. By identifying a class of thermoplastic hydrogels, a strategy is developed to pattern hydrogels in thermally drawn fibers.
Changhoon Sung, Kum Seok Nam, Yeji Kim, Honey Kang, Kanghyeon Kim, Chanwoong Yoon, Somin Lee, Ain Chung, Jiheong Kang, Young‐Gyun Park, Alan Jung Park, Haider Butt, Hyunwoo Yuk, Seongjun Park   +13 more
wiley   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

Hepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei   +9 more
wiley   +1 more source

The effect of microinjection of dimethyl sulfoxide into the rostral ventromedial medulla on swim stress-induced analgesia [PDF]

The Journal of Qazvin University of Medical Sciences, 2018
Background: Dimethyl sulfoxide (DMSO) is an important solvent for compounds that used in pain research. Rostral ventromedial medulla (RVM) plays an important role in modulating nociception and stress-induced analgesia (SIA).
S. Nazemi, A. Shamsizadeh, N. Haidari-Oranji, N. Soleimani, H. Azhdari Zarmehri   +4 more
doaj   +1 more source

Does the midbrain dorsolateral periaqueductal grey have direct connections with the pontine A5 region? A neuropharmacologic and electrophysiological study [PDF]

, 2018
This study has been performed in spontaneously breathing anesthetised rats. We have analysed the possible interactions between the midbrain dorsolateral periaqueductal grey matter (dlPAG) and the pontine A5 region. Electrical stimulations of the dlPAG (1
Barbancho-Fernandez, Miguel Angel, Dawid-Milner, Marc Stefan, Díaz-Casares, Amelia, González-García, Marta, López-González, Manuel Víctor, Peinado-Aragonés, Carlos Antonio   +5 more
core  

Distinct sites of opiate reward and aversion within the midbrain identified using a herpes simplex virus vector expressing GluR1 [PDF]

, 2000
Repeated administration of morphine increases expression of GluR1 (an AMPA glutamate receptor subunit) in the ventral tegmental area (VTA) of the midbrain, an important neural substrate for the rewarding actions of morphine.
Carlezon, W. A., Coopersmith, R., Haile, C. N., Hayashi, Y., Malinow, R., Nestler, E. J., Neve, R. L.   +6 more
core   +1 more source

Moth‐Wing‐Inspired Multifunctional Metamaterials

Advanced Materials, EarlyView.
This study develops a moth‐wing‐inspired heterogeneous metamaterial that achieves synergistic broadband sound absorption, mechanical energy dissipation, and thermal insulation within a lightweight architected framework. Combining bioinspired gradient design, genetic‐algorithm optimization, and additive manufacturing, the bionic heterogeneous acoustic ...
Haoran Pei, Hang Yang, Ning Zhang, Tian Li, Xinxin Wang, Miao Zhao, Shuwei Ding, Xin Wang, Qinniu Lv, Zijie Xu, Yinghong Chen, Xinwei Li, Wei Zhai   +12 more
wiley   +1 more source

A Hypothalamic Leptin-Glutamate Interaction in the Regulation of Sympathetic Nerve Activity

Neural Plasticity, 2017
Accumulated evidence indicates that obesity-induced type 2 diabetes (T2D) is associated with enhanced sympathetic activation. The present study was conducted to investigate the role for leptin-glutamate signaling within the hypothalamus in regulating ...
Hong Zheng, Xuefei Liu, Yulong Li, Kaushik P. Patel   +3 more
doaj   +1 more source

Agonistic-like responses from the torus semicircularis dorsalis elicited by GABA A blockade in the weakly electric fish Gymnotus carapo

Brazilian Journal of Medical and Biological Research, 2006
Findings by our group have shown that the dorsolateral telencephalon of Gymnotus carapo sends efferents to the mesencephalic torus semicircularis dorsalis (TSd) and that presumably this connection is involved in the changes in electric organ discharge ...
T.T. Duarte, S.A.L. Corrêa, U.J. Santana, A.S.F. Pereira, A. Hoffmann   +4 more
doaj   +1 more source