Dopamine or opioid stimulation of nucleus accumbens similarly amplify cue‐triggered ‘wanting’ for reward: entire core and medial shell mapped as substrates for PIT enhancement [PDF]
, 2013 Pavlovian cues [conditioned stimulus ( CS +)] often trigger intense motivation to pursue and consume related reward [unconditioned stimulus ( UCS )]. But cues do not always trigger the same intensity of motivation.
Berridge, Kent C., Peciña, Susana
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Thermal Plasticity is Regulated by a Key MicroRNA During Range Expansion of an Invasive Fruit Fly
Advanced Science, EarlyView.Populations at the invasion front of Bactrocera dorsalis adapt through reduced phenotypic and gene expression plasticity, a phenomenon likely to be driven by genetic assimilation. We identify a key miRNA‐mediated regulatory axis, in which miR‐276b post‐transcriptionally represses thw, a conserved chitin‐binding gene critical to the cold‐tolerance ...
Yan Zhao +5 more
wiley +1 more source
Hydrogen sulphide in the RVLM and PVN has no effect on cardiovascular regulation
Frontiers in Physiology, 2011 Hydrogen Sulphide (H2S) is now recognised as an important signalling molecule and has been shown to have vasodilator and cardio-protectant effects. More recently it has been suggested that H2S may also act within the brain to reduce blood pressure.
Eloise eStreeter +3 more
doaj +1 more source
Mapping a Novel Hedonic Hotspot in the Orbitofrontal Cortex [PDF]
, 2014 Honors (Bachelor's)PsychologyUniversity of Michiganhttp://deepblue.lib.umich.edu/bitstream/2027.42/107703/1/mikewkh ...
Wu, Kuan Hua
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Role of Thalamic Projection in NMDA Receptor-Induced Disruption of Cortical Slow Oscillation and Short-Term Plasticity [PDF]
, 2011 NMDA receptor (NMDAR) antagonists, such as phencyclidine, ketamine or dizocilpine (MK-801) are commonly used in psychiatric drug discovery in order to model several symptoms of schizophrenia, including psychosis and impairments in working memory.
Tamás Kiss +6 more
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Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders
Advanced Science, EarlyView.In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang +22 more
wiley +1 more source
Hepatology, EarlyView., 2022 Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong +9 more
wiley +1 more source
Microinjections observed by MMS FEEPS in the dusk to midnight region
Geophysical Research Letters, 2016 Energetic electron injections are commonly observed in the premidnight to dawn regions in association with substorms. However, successive electron injections are generally separated in time by hours and are rarer in the dusk region of the inner ...
J. F. Fennell +17 more
doaj +1 more source
Evidence for energetic electron and iondispersive microinjections in theEarth's magnetotail as far as 27 RE [PDF]
Annales Geophysicae, 2004 High energy and time resolution measurements of energetic electron and ion fluxes obtained by the DOK-2 experiment on board the Interball-tail satellite provide us the opportunity to study the short-lived (1–3min), localized, and often periodic and ...
D. V. Sarafopoulos +2 more
doaj +1 more source
Effect of scopolamine-based amnesia on the number of astrocytes in the rat's hippocampus [PDF]
, 2012 As neuron-astrocyte interactions play a crucial role in the adult brain, it is thought that astrocytes support learning and memory through specific mechanisms.
Azami, N.S. +2 more
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